-
1
-
-
0025166005
-
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma
-
Saito I, Miyamura T, Ohbayashi A, Harada H, Katayama T, Kikuchi S, Watanabe Y, Koi S, Onji M, Ohta Y, Choo Q, Houghton M, Kuo G. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A 1990;87:6547-6549.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6547-6549
-
-
Saito, I.1
Miyamura, T.2
Ohbayashi, A.3
Harada, H.4
Katayama, T.5
Kikuchi, S.6
Watanabe, Y.7
Koi, S.8
Onji, M.9
Ohta, Y.10
Choo, Q.11
Houghton, M.12
Kuo, G.13
-
2
-
-
0026599783
-
Hepatitis C virus infection as a risk factor for hepatocellular carcinoma in patients with cirrhosis
-
Simonetti RG, Camma C, Fiorello F, Cottone M, Rapicetta M, Marino L, Fiorentino G, Craxi A, Ciccaglione A, Giuseppetti R, Stroffolini T, Pagliaro L. Hepatitis C virus infection as a risk factor for hepatocellular carcinoma in patients with cirrhosis. Ann Intern Med 1992;116:97-102.
-
(1992)
Ann Intern Med
, vol.116
, pp. 97-102
-
-
Simonetti, R.G.1
Camma, C.2
Fiorello, F.3
Cottone, M.4
Rapicetta, M.5
Marino, L.6
Fiorentino, G.7
Craxi, A.8
Ciccaglione, A.9
Giuseppetti, R.10
Stroffolini, T.11
Pagliaro, L.12
-
3
-
-
0028876341
-
Hepatitis C: A multifaceted disease
-
Gumber SC, Chopra S. Hepatitis C: a multifaceted disease. Ann Intern Med 1995;123:615-620.
-
(1995)
Ann Intern Med
, vol.123
, pp. 615-620
-
-
Gumber, S.C.1
Chopra, S.2
-
4
-
-
0028618516
-
Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population
-
Allison ME, Wreghitt T, Palmer CR, Alexander GJ. Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population. J Hepatol 1994;21:1135-1139.
-
(1994)
J Hepatol
, vol.21
, pp. 1135-1139
-
-
Allison, M.E.1
Wreghitt, T.2
Palmer, C.R.3
Alexander, G.J.4
-
5
-
-
0032835659
-
Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection
-
Caronia S, Taylor K, Pagliaro L, Carr C, Palazzo U, Petrik J, O'Rahilly S, Shore S, Tom BD, Alexander GJ. Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection. Hepatology 1999;30:1059-1063.
-
(1999)
Hepatology
, vol.30
, pp. 1059-1063
-
-
Caronia, S.1
Taylor, K.2
Pagliaro, L.3
Carr, C.4
Palazzo, U.5
Petrik, J.6
O'Rahilly, S.7
Shore, S.8
Tom, B.D.9
Alexander, G.J.10
-
6
-
-
0033025254
-
Association of diabetes mellitus and chronic hepatitis C virus infection
-
Mason AL, Lau JY, Hoang N, Qian K, Alexander GJ, Xu L, Guo L, Jacob S, Regenstein FG, Zimmerman R, Everhart JE, Wasserfall C, Maclaren NK, Perrillo RP. Association of diabetes mellitus and chronic hepatitis C virus infection. Hepatology 1999;29:328-333.
-
(1999)
Hepatology
, vol.29
, pp. 328-333
-
-
Mason, A.L.1
Lau, J.Y.2
Hoang, N.3
Qian, K.4
Alexander, G.J.5
Xu, L.6
Guo, L.7
Jacob, S.8
Regenstein, F.G.9
Zimmerman, R.10
Everhart, J.E.11
Wasserfall, C.12
Maclaren, N.K.13
Perrillo, R.P.14
-
7
-
-
0033779703
-
Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States
-
Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med 2000;133:592-599.
-
(2000)
Ann Intern Med
, vol.133
, pp. 592-599
-
-
Mehta, S.H.1
Brancati, F.L.2
Sulkowski, M.S.3
Strathdee, S.A.4
Szklo, M.5
Thomas, D.L.6
-
8
-
-
0032489358
-
Type 2 diabetes: When insulin secretion fails to compensate for insulin resistance
-
Kahn BB. Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 1998;92:593-596.
-
(1998)
Cell
, vol.92
, pp. 593-596
-
-
Kahn, B.B.1
-
9
-
-
0033842027
-
Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
-
Cavaghan MK, Ehrmann DA, Polonsky KS. Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest 2000;106:329-333.
-
(2000)
J Clin Invest
, vol.106
, pp. 329-333
-
-
Cavaghan, M.K.1
Ehrmann, D.A.2
Polonsky, K.S.3
-
10
-
-
0031712813
-
Hepatitis C virus core protein induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Matsuura Y, Kimura S, Miyamura T, Koike K. Hepatitis C virus core protein induces hepatocellular carcinoma in transgenic mice. Nat Med 1998;4:1065-1068.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1068
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
Yotsuyanagi, H.4
Tsutsumi, T.5
Matsuura, Y.6
Kimura, S.7
Miyamura, T.8
Koike, K.9
-
11
-
-
0030859121
-
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
-
Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, Miyamura T, Koike K. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 1997;78:1527-1531.
-
(1997)
J Gen Virol
, vol.78
, pp. 1527-1531
-
-
Moriya, K.1
Yotsuyanagi, H.2
Shintani, Y.3
Fujie, H.4
Ishibashi, K.5
Matsuura, Y.6
Miyamura, T.7
Koike, K.8
-
12
-
-
0031034119
-
Sialadenitis resembling Sjögren's syndrome in mice transgenic for hepatitis C virus envelope genes
-
Koike K, Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, Kurokawa K, Miyamura T. Sialadenitis resembling Sjögren's syndrome in mice transgenic for hepatitis C virus envelope genes. Proc Natl Acad Sci U S A 1997;94:233-236.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 233-236
-
-
Koike, K.1
Moriya, K.2
Yotsuyanagi, H.3
Shintani, Y.4
Fujie, H.5
Ishibashi, K.6
Matsuura, Y.7
Kurokawa, K.8
Miyamura, T.9
-
13
-
-
12244276796
-
Intrahepatic cytokine expression and AP-1 activation in mice transgenic for hepatitis C virus core protein
-
Tsutsumi T, Suzuki T, Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Matsuura Y, Kimura S, Koike K, Miyamura T. Intrahepatic cytokine expression and AP-1 activation in mice transgenic for hepatitis C virus core protein. Virology 2002;304:415-424.
-
(2002)
Virology
, vol.304
, pp. 415-424
-
-
Tsutsumi, T.1
Suzuki, T.2
Moriya, K.3
Yotsuyanagi, H.4
Shintani, Y.5
Fujie, H.6
Matsuura, Y.7
Kimura, S.8
Koike, K.9
Miyamura, T.10
-
14
-
-
0035067956
-
Frequent β-catenin aberration in human hepatocellular carcinoma
-
Fujie H, Moriya K, Shintani Y, Tsutsumi T, Takayama T, Makuuchi M, Kimura S, Koike K. Frequent β-catenin aberration in human hepatocellular carcinoma. Hepatol Res 2001;20:39-51.
-
(2001)
Hepatol Res
, vol.20
, pp. 39-51
-
-
Fujie, H.1
Moriya, K.2
Shintani, Y.3
Tsutsumi, T.4
Takayama, T.5
Makuuchi, M.6
Kimura, S.7
Koike, K.8
-
15
-
-
0028817712
-
Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice
-
Ren JM, Marshall BA, Mueckler MM, McCaleb M, Amatruda JM, Shulman GI. Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. J Clin Invest 1995;95:429-432.
-
(1995)
J Clin Invest
, vol.95
, pp. 429-432
-
-
Ren, J.M.1
Marshall, B.A.2
Mueckler, M.M.3
McCaleb, M.4
Amatruda, J.M.5
Shulman, G.I.6
-
16
-
-
0032510947
-
Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle
-
Brozinick T Jr, Birnbaum MJ. Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle. J Biol Chem 1998;273:14679-14682.
-
(1998)
J Biol Chem
, vol.273
, pp. 14679-14682
-
-
Brozinick Jr., T.1
Birnbaum, M.J.2
-
17
-
-
0034671575
-
Evaluation of TNF-alpha and IL-1 blockade in collagen-induced arthritis and comparison with combined anti-TNF-alpha/anti-CD4 therapy
-
Williams RO, Marinova-Mutafchieva L, Feldmann M, Maini RN. Evaluation of TNF-alpha and IL-1 blockade in collagen-induced arthritis and comparison with combined anti-TNF-alpha/anti-CD4 therapy. J Immunol 2000;165:7240-7245.
-
(2000)
J Immunol
, vol.165
, pp. 7240-7245
-
-
Williams, R.O.1
Marinova-Mutafchieva, L.2
Feldmann, M.3
Maini, R.N.4
-
18
-
-
0030596338
-
Seminars in medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus-a genetically programmed failure of the beta cell to compensate for insulin resistance
-
Polonsky KS, Sturis J, Bell GI. Seminars in medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus-a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med 1996;334:777-783.
-
(1996)
N Engl J Med
, vol.334
, pp. 777-783
-
-
Polonsky, K.S.1
Sturis, J.2
Bell, G.I.3
-
19
-
-
0030451387
-
Hepatomegaly and abnormal liver tests due to glycogenosis in adults with diabetes
-
Chatila R, West AB. Hepatomegaly and abnormal liver tests due to glycogenosis in adults with diabetes. Medicine (Baltimore) 1996;75:327-333.
-
(1996)
Medicine (Baltimore)
, vol.75
, pp. 327-333
-
-
Chatila, R.1
West, A.B.2
-
20
-
-
0029585099
-
Expression of hepatitis C virus envelope proteins in transgenic mice
-
Koike K, Moriya K, Ishibashi K, Matsuura Y, Suzuki T, Saito I, Iino S, Kurokawa K, Miyamura T. Expression of hepatitis C virus envelope proteins in transgenic mice. J Gen Virol 1995;76:3031-3038.
-
(1995)
J Gen Virol
, vol.76
, pp. 3031-3038
-
-
Koike, K.1
Moriya, K.2
Ishibashi, K.3
Matsuura, Y.4
Suzuki, T.5
Saito, I.6
Iino, S.7
Kurokawa, K.8
Miyamura, T.9
-
21
-
-
0036292006
-
Role of hepatitis viruses in hepatocarcinogenesis
-
Koike K, Tsutsumi T, Fujie H, Shintani Y, Moriya K. Role of hepatitis viruses in hepatocarcinogenesis. Oncology 2002;62:29-37.
-
(2002)
Oncology
, vol.62
, pp. 29-37
-
-
Koike, K.1
Tsutsumi, T.2
Fujie, H.3
Shintani, Y.4
Moriya, K.5
-
22
-
-
0034979117
-
Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy
-
Polyak SJ, Khabar KS, Rezeiq M, Gretch DR. Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol 2001;75:6209-6211.
-
(2001)
J Virol
, vol.75
, pp. 6209-6211
-
-
Polyak, S.J.1
Khabar, K.S.2
Rezeiq, M.3
Gretch, D.R.4
-
23
-
-
0031887203
-
Induction of tumour necrosis factor (TNF) receptor type p55 and p75 in patients with chronic hepatitis C virus (HCV) infection
-
Kallinowski B, Haseroth K, Marinos G, Hanck C, Stremmel W, Theilmann L, Singer MV, Rossol S. Induction of tumour necrosis factor (TNF) receptor type p55 and p75 in patients with chronic hepatitis C virus (HCV) infection. Clin Exp Immunol 1998;111:269-277.
-
(1998)
Clin Exp Immunol
, vol.111
, pp. 269-277
-
-
Kallinowski, B.1
Haseroth, K.2
Marinos, G.3
Hanck, C.4
Stremmel, W.5
Theilmann, L.6
Singer, M.V.7
Rossol, S.8
-
24
-
-
0031427384
-
Activation of tumor necrosis factor-alpha system in chronic hepatitis C virus infection
-
Nelson DR, Lim HL, Marousis CG, Fang JW, Davis GL, Shen L, Urdea MS, Kolberg JA, Lau JY. Activation of tumor necrosis factor-alpha system in chronic hepatitis C virus infection. Dig Dis Sci 1997;42:2487-2494.
-
(1997)
Dig Dis Sci
, vol.42
, pp. 2487-2494
-
-
Nelson, D.R.1
Lim, H.L.2
Marousis, C.G.3
Fang, J.W.4
Davis, G.L.5
Shen, L.6
Urdea, M.S.7
Kolberg, J.A.8
Lau, J.Y.9
-
26
-
-
0033867178
-
Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes
-
Moller DE. Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab 2000;11:212-217.
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 212-217
-
-
Moller, D.E.1
-
27
-
-
0035034309
-
Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells
-
Halse R, Pearson SL, McCormack JG, Yeaman SJ, Taylor R. Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells. Diabetes 2001;50:1102-1109.
-
(2001)
Diabetes
, vol.50
, pp. 1102-1109
-
-
Halse, R.1
Pearson, S.L.2
McCormack, J.G.3
Yeaman, S.J.4
Taylor, R.5
-
28
-
-
0035055823
-
Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with type 2 diabetes mellitus
-
Mishima Y, Kuyama A, Tada A, Takahashi K, Ishioka T, Kibata M. Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with type 2 diabetes mellitus. Diabetes Res Clin Pract 2001;52:119-123.
-
(2001)
Diabetes Res Clin Pract
, vol.52
, pp. 119-123
-
-
Mishima, Y.1
Kuyama, A.2
Tada, A.3
Takahashi, K.4
Ishioka, T.5
Kibata, M.6
-
29
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610-614.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
30
-
-
0032587240
-
The role of TNF alpha and TNF receptors in obesity and insulin resistance
-
Hotamisligil GS. The role of TNF alpha and TNF receptors in obesity and insulin resistance. J Intern Med 1999;245:621-625.
-
(1999)
J Intern Med
, vol.245
, pp. 621-625
-
-
Hotamisligil, G.S.1
-
31
-
-
0035836770
-
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1
-
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dizon JE, Donner DB. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. Proc Natl Acad Sci U S A 2001;98:4640-4645.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4640-4645
-
-
Ozes, O.N.1
Akca, H.2
Mayo, L.D.3
Gustin, J.A.4
Maehama, T.5
Dizon, J.E.6
Donner, D.B.7
-
32
-
-
0034708832
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
-
Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000;275:9047-9054.
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
33
-
-
0030669094
-
Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612
-
De Fea K, Roth RA. Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612. Biochemistry 1997;36:12939-12947.
-
(1997)
Biochemistry
, vol.36
, pp. 12939-12947
-
-
De Fea, K.1
Roth, R.A.2
-
34
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael MD, Kulkarni RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn CR. Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol Cell 2000;6:87-97.
-
(2000)
Mol Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkarni, R.N.2
Postic, C.3
Previs, S.F.4
Shulman, G.I.5
Magnuson, M.A.6
Kahn, C.R.7
-
35
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science 2001;292:1728-1731.
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw III, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
36
-
-
18244365866
-
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
-
Perlemuter G, Sabile A, Letteron P, Topilco Samson-Bouna M-E, Chretien Y, Pessayre D, Koike K, Chapman J, Barba G, Brechot C. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 2002;16:185-194.
-
(2002)
FASEB J
, vol.16
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
Topilco Samson-Bouna, M.-E.4
Chretien, Y.5
Pessayre, D.6
Koike, K.7
Chapman, J.8
Barba, G.9
Brechot, C.10
-
37
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000;206:473-481.
-
(2000)
J Clin Invest
, vol.206
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
38
-
-
0033849842
-
Insight into insulin resistance and type 2 diabetes from knockout mouse models
-
Kadowaki T. Insight into insulin resistance and type 2 diabetes from knockout mouse models. J Clin Invest 2000;206:459-465.
-
(2000)
J Clin Invest
, vol.206
, pp. 459-465
-
-
Kadowaki, T.1
-
39
-
-
0029065480
-
Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice
-
Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, Opara EC, Kuhn CM, Rebuffe-Scrive M. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 1995;44:645-651.
-
(1995)
Metabolism
, vol.44
, pp. 645-651
-
-
Surwit, R.S.1
Feinglos, M.N.2
Rodin, J.3
Sutherland, A.4
Petro, A.E.5
Opara, E.C.6
Kuhn, C.M.7
Rebuffe-Scrive, M.8
-
40
-
-
0034063375
-
Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes
-
Devedjian JC, George M, Casellas A, Pujol A, Visa J, Pelegrin M, Gros L, Bosch F. Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes. J Clin Invest 2000;105:731-740.
-
(2000)
J Clin Invest
, vol.105
, pp. 731-740
-
-
Devedjian, J.C.1
George, M.2
Casellas, A.3
Pujol, A.4
Visa, J.5
Pelegrin, M.6
Gros, L.7
Bosch, F.8
|