Activation of tumor necrosis factor-α system in chronic hepatitis C virus infection

Digestive Diseases and Sciences

Volumn 42, Issue 12, 1997, Pages 2487-2494

  Nelson, David R ^b   Lim, Herbert L ^b   Marousis, Constantine G ^b   Fang, Jane W S ^b   Davis, Gary L ^b   Shen, Luping ^b   Urdea, Mickey S ^b   Kolberg, Janice A ^b   Lau, Johnson Y N ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

Cytokines; Hepatitis C; Hepatitis C virus; Pathogenesis; Peripheral blood mononuclear cells; Receptors; Tumor necrosis factor

Indexed keywords

ALANINE AMINOTRANSFERASE; CYTOKINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; ENZYME IMMUNOASSAY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LIVER CELL DAMAGE; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ALANINE TRANSAMINASE; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER; MALE; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; RNA, VIRAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031427384     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018804426724     Document Type: Article

References (28)

1. Camussi G, Albano E, Tetta C, Bussolino F: The molecular action of tumor necrosis factor alpha. Eur J Biochem 202:3-14, 1991
2. Dinarello CA, Mier JW: Current concepts, lymphokines. N Engl J Med 317:940-945, 1987
3. Aria K, Lee F, Miyajima A, Argi N, Yokota T: Cytokines: Coordinators of immune and inflammatory responses. Annu Rev Biochem 59:783-836, 1990
4. Kull FC: The TNF receptor in TNF-mediatcd cytotoxicity. Nat Cell Growth Regul 7:254-265, 1988
5. Scheurich P, Thoma B, Ucer U, Pfizenmaier K: Immunoregulatory activity of recombinant TNF-alpha: Induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses. J Immunol 138:1786-1790, 1987
6. Lau JYN: Hepatitis C virus: From epidemiology and molecular virology to immunobiology. Hepatology 20:760-762, 1994
7. Onji M, Kikuchi T, Kumon I, Masumoto T, Nadano S, Kajino K, Ohta Y: Intrahepatic lymphocyte subpopulations and HLA class I antigen expression by hepatocytes in chronic hepatitis C. Hepato-Gastroenterol 108:231, 1992
8. Nelson DR, Marousis CG, Davis GL, Rice CM, Wong J, Houghton M, Lau JYN: The role of intrahepatic HCV-specific cytotoxic T cell lymphocytes in chronic hepatitis C. J Immunol 158:1473-1481, 1997
9. Nelson DR, Lim HL, Oliver D, Qian KP, Davis GL, Lau JYN: α-Glutathione S-transferase: Analysis of its utility in chronic hepatitis C virus infection. Am J Clin Pathol 104:193-198, 1995
10. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan, et al: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1:431, 1981
11. Lau JYN, Davis GL, Brunson ME, Qian KP, Lin HJ, Quan S, DiNello R, Polito AJ, Scornik JC: Hepatitis C virus infection in renal transplant recipients. Hepatology 18:1027-1031, 1993
12. Lau JYN, Simmonds P, Urdea MS: Implications of variations of conserved regions of hepatitis C virus genome. Lancet 346:425, 1995
13. Stuyver L, Rossau R, Wyseur A, Duhamel M, Vanderborght B, Van Heuverswyn H, et al: Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol 74:1093-102, 1993
14. Simmonds P, Alberti A, Bonino F, Bradley DW, Brechot C, Chan SW, et al: A proposed nomenclature system of genotypes for hepatitis C virus. Hepatology 19:1321-1324, 1994
15. Kapadia S, Guillermo TA, Mann D: Pitfalls in measuring cytokines. Ann Intern Med 121:149-150, 1994
16. Urdea MS, Horn T, Fultz TJ, Anderson M, Running JA, Hamren S, et al: Branched DNA amplification multimers for the sensitive, direct detection of human hepatitis viruses. Nucleic Acid Symp Ser 23:197-200, 1993
17. Tilg H, Wilmer A, Vogel W, Herold M, Nolchen B, Judamaier G, Huber C: Serum levels of cytokines in chronic liver diseases. Gastroenterology 103:264-274, 1992
18. Larrea E, Garcia N, Qian C, Civeira M, Prieto J: TNF-α gene expression and the response to Interferon in chronic hepatitis C. Hepatology 2:210-217, 1996
19. Becker S, Quay J, Soukup J: Cytokine (tumor necrosis factor, IL-6, and IL-8) production by respiratory syncytial virus-infected human alveolar macrophages. J Immunol 147:4307-4312, 1991
20. Gosselin J, Flamand L, D'Addario M, Hiscott J, Menezes J: Infection of peripheral blood mononuclear cells by herpes simplex and Epstein-Barr viruses. Differential induction of interleukin 6 and tumor necrosis factor-alpha. J Clin Invest 89:1849-1856, 1992
21. Henke A, Mohr C, Sprenger H, Graibner C, Stelzner A, Nain M, Gemsa D: Coxsackie virus B3-induced production of timor necrosis factor-alpha, IL-1 beta, and IL-6 in human monocytes. J Immunol 148:2270-2277, 1992
22. Sheron N, Lau J, Daniels H, Goka J, Eddleston A, Alexander GM, Williams R: Increased production of tumor necrosis factor alpha in chronic hepatitis B virus infection. J Hepatol 12:241-245, 1991
23. Kishihara Y, Hayashi J, Yoshimura E, Yamaji K, Nakashima K, Kashiwagi S: IL-1 and TNF-α produced by peripheral blood mononuclear cells before and during interferon therapy in patients with chronic hepatitis C. Dig Dis Sci 41:315-321, 1996
24. Gonzalez-Amaro R, Garcia-Monzon C, Garcia-Buey L, Moreno-Otero R, Alonso JL, Yague E, Pivel JP, Fernandez-Ruiz E, Lopez-Cabrera M, Sanchez-Madrid F: Induction of tumor necrosis factor-alpha production by human hepatocytes in chronic viral hepatitis. J Exp Med 179:841-848, 1994
25. Shinagawa T, Yoshioka K, Kakumu A, Wakita T, Ishikawa T, Itoh Y, Takayanagi M: Apoptosis in cultured rat hepatocytes: The effects of tumor necrosis factor alpha and interferon gamma. J Pathol 165:247-253, 1991
26. Koziel MJ, Dudley D, Afdhal N, Choo QL, Houghton M, Ralston R, Walker B: Hepatitis C virus-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV. J Virol 67:7522-7532, 1993
27. Kozeil MJ, Dudley D, Afdel A, Grakoui A, Rice CM, Choo QL, Houghton M, Walker BD: HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C Virus. J Clin Invest 96:2311-2321, 1995
28. Volpes R, van-den-Oord JJ, De-Vos R, Desmet VJ: Hepatic expression of type A and type B receptors for tumor necrosis factor. J Hepatol 14:361-369, 1992