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Volumn 24, Issue 6, 2004, Pages 3899-3905

Functional analysis of focal adhesion kinase (FAK) reduction by small inhibitory RNAs

Author keywords

Adhesion; Extracellular matrix; Focal adhesion kinase

Indexed keywords

AGAR; CHEMOATTRACTANT; EPIDERMAL GROWTH FACTOR; FOCAL ADHESION KINASE; GROWTH FACTOR; INTEGRIN; NEUROPEPTIDE; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; FOCAL ADHESION KINASE 1; PTK2 PROTEIN, HUMAN;

EID: 14944377114     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (42)

References (30)
  • 1
    • 0035948579 scopus 로고    scopus 로고
    • Biochemical signals and biological responses elicited by the focal adhesion kinase
    • Schaller MD: Biochemical signals and biological responses elicited by the focal adhesion kinase. Biochim Biophys Acta 1540: 1-21, 2001.
    • (2001) Biochim Biophys Acta , vol.1540 , pp. 1-21
    • Schaller, M.D.1
  • 2
    • 0034693854 scopus 로고    scopus 로고
    • Focal adhesion kinase: A regulator of focal adhesion dynamics and cell movement
    • Parsons JT, Martin KH, Slack JK, Taylor JM and Weed SA: Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement. Oncogene 19: 5606-5613, 2000.
    • (2000) Oncogene , vol.19 , pp. 5606-5613
    • Parsons, J.T.1    Martin, K.H.2    Slack, J.K.3    Taylor, J.M.4    Weed, S.A.5
  • 3
    • 0038048222 scopus 로고    scopus 로고
    • FAK regulates biological processes important for the pathogenesis of cancer
    • Gabarra-Niecko V, Schaller MD and Dunty JM: FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metast Rev 22: 359-374, 2003.
    • (2003) Cancer Metast Rev , vol.22 , pp. 359-374
    • Gabarra-Niecko, V.1    Schaller, M.D.2    Dunty, J.M.3
  • 5
    • 0027439594 scopus 로고
    • Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK
    • Schaller MD, Borgman CA and Parsons JT: Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK. Mol Cell Biol 13: 785-791, 1993.
    • (1993) Mol Cell Biol , vol.13 , pp. 785-791
    • Schaller, M.D.1    Borgman, C.A.2    Parsons, J.T.3
  • 6
    • 0032443850 scopus 로고    scopus 로고
    • The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
    • Xu LH, Yang X, Craven RJ and Cance WG: The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth Differ 9: 999-1005, 1999.
    • (1999) Cell Growth Differ , vol.9 , pp. 999-1005
    • Xu, L.H.1    Yang, X.2    Craven, R.J.3    Cance, W.G.4
  • 7
    • 0037011055 scopus 로고    scopus 로고
    • FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
    • Hauck CR, Hsia DA, Puente XS, Cheresh DA and Schlaepfer DD: FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth. EMBO J 21: 6289-6302, 2002.
    • (2002) EMBO J , vol.21 , pp. 6289-6302
    • Hauck, C.R.1    Hsia, D.A.2    Puente, X.S.3    Cheresh, D.A.4    Schlaepfer, D.D.5
  • 8
    • 0035476836 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
    • Hauck CR, Sieg DJ, Hsia DA, Loftus JC, Gaarde WA, Monia BP and Schlaepfer DD: Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Can Res 61: 7079-7090, 2001.
    • (2001) Can Res , vol.61 , pp. 7079-7090
    • Hauck, C.R.1    Sieg, D.J.2    Hsia, D.A.3    Loftus, J.C.4    Gaarde, W.A.5    Monia, B.P.6    Schlaepfer, D.D.7
  • 9
    • 0037233708 scopus 로고    scopus 로고
    • The effects of inducible overexpression of FAK-related non-kinase (FRNK) on a transformed epithelial cell line
    • Kornberg L and Fleigel J: The effects of inducible overexpression of FAK-related non-kinase (FRNK) on a transformed epithelial cell line. Anticancer Res 23: 91-97, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 91-97
    • Kornberg, L.1    Fleigel, J.2
  • 10
    • 0037188927 scopus 로고    scopus 로고
    • GFP-FRNK disrupts focal adhesions and induces anoikis in neonatal rat ventricular myocytes
    • Heidkamp MC, Bayer AL, Kalina JA, EbIe DM and Samarel AM: GFP-FRNK disrupts focal adhesions and induces anoikis in neonatal rat ventricular myocytes Circ Res 90: 1282-1289, 2002.
    • (2002) Circ Res , vol.90 , pp. 1282-1289
    • Heidkamp, M.C.1    Bayer, A.L.2    Kalina, J.A.3    EbIe, D.M.4    Samarel, A.M.5
  • 11
    • 0032784060 scopus 로고    scopus 로고
    • Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase
    • Nolan E, Lacoste J and Parsons JT: Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase. Mol Cell Biol 19: 6120-6129, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 6120-6129
    • Nolan, E.1    Lacoste, J.2    Parsons, J.T.3
  • 12
    • 0242493171 scopus 로고    scopus 로고
    • RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
    • Duxbury MS, Hiromichi I, Benoit E, Zinner MJ, Ashley SW and Whang EE: RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem Biophy Res Com 311: 786-792, 2003.
    • (2003) Biochem Biophy Res Com , vol.311 , pp. 786-792
    • Duxbury, M.S.1    Hiromichi, I.2    Benoit, E.3    Zinner, M.J.4    Ashley, S.W.5    Whang, E.E.6
  • 13
    • 0034717285 scopus 로고    scopus 로고
    • Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line HL60
    • Sonoda Y, Matsumoto Y, Megumi F, Yamamoto D, Hanks SK and Kasahara T: Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line HL60. J Biol Chem 276: 16309-16315, 2000.
    • (2000) J Biol Chem , vol.276 , pp. 16309-16315
    • Sonoda, Y.1    Matsumoto, Y.2    Megumi, F.3    Yamamoto, D.4    Hanks, S.K.5    Kasahara, T.6
  • 14
    • 0029166094 scopus 로고
    • Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase
    • Bellis SL, Miller JT and Turner CD: Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J Biol Chem 270: 17437-17441, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 17437-17441
    • Bellis, S.L.1    Miller, J.T.2    Turner, C.D.3
  • 15
    • 0030793696 scopus 로고    scopus 로고
    • Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin
    • Bellis SL, Perrotta JA, Curtis MS and Turner CE: Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin. Biochem J 325: 375-381, 1997.
    • (1997) Biochem J , vol.325 , pp. 375-381
    • Bellis, S.L.1    Perrotta, J.A.2    Curtis, M.S.3    Turner, C.E.4
  • 16
    • 0035826165 scopus 로고    scopus 로고
    • Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
    • Slack JK, Adams RB, Rovin JD, Bissonette EA, Stoker CE and Parsons JT: Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene 20: 1151-1163, 2001.
    • (2001) Oncogene , vol.20 , pp. 1151-1163
    • Slack, J.K.1    Adams, R.B.2    Rovin, J.D.3    Bissonette, E.A.4    Stoker, C.E.5    Parsons, J.T.6
  • 17
    • 0032820782 scopus 로고    scopus 로고
    • Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
    • Sieg DJ, Hauck CR and Schlaepfer DD: Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci 112: 2677-2691, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 2677-2691
    • Sieg, D.J.1    Hauck, C.R.2    Schlaepfer, D.D.3
  • 18
    • 0035137373 scopus 로고    scopus 로고
    • Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells
    • Taylor JM, Mack CP, Nolan K, Regan CP, Owens GK and Parsons JT: Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells. Mol Cell Biol 21: 1565-1572, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 1565-1572
    • Taylor, J.M.1    Mack, C.P.2    Nolan, K.3    Regan, C.P.4    Owens, G.K.5    Parsons, J.T.6
  • 19
    • 0042242786 scopus 로고    scopus 로고
    • Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death
    • Walsh MF, Thamilselvan V, Grotelueschen R, Farhana L and Basson MC: Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death. Cell Physiol Bochem 13: 135-146, 2003.
    • (2003) Cell Physiol Bochem , vol.13 , pp. 135-146
    • Walsh, M.F.1    Thamilselvan, V.2    Grotelueschen, R.3    Farhana, L.4    Basson, M.C.5
  • 20
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary LA, Chang JF and Guan JL: Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. Cell Sci 109: 1787-1794, 1996.
    • (1996) Cell Sci , vol.109 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.L.3
  • 21
    • 0036789666 scopus 로고    scopus 로고
    • Expression of focal adhesion kinase in normal and pathologic human prostate tissues
    • Rovin JD, Frierson HFJr, Ledinh W, Parsons JT and Adams RB: Expression of focal adhesion kinase in normal and pathologic human prostate tissues. Prostate 53: 124-132, 2002
    • (2002) Prostate , vol.53 , pp. 124-132
    • Rovin, J.D.1    Frierson Jr., H.F.2    Ledinh, W.3    Parsons, J.T.4    Adams, R.B.5
  • 22
    • 0034044795 scopus 로고    scopus 로고
    • Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
    • Cance WG, Harris JE, Iacocca MV, Roche E, Yang X, Chang J, Simkins S and Xu L: Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res 6: 2417-2423, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 2417-2423
    • Cance, W.G.1    Harris, J.E.2    Iacocca, M.V.3    Roche, E.4    Yang, X.5    Chang, J.6    Simkins, S.7    Xu, L.8
  • 23
    • 0031112814 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: Independence from c-src or c-yes activation
    • Han HM, Fleming RY, Curley SA and Gallick GE: Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation. Ann Surg Oncol 4: 264-268, 1997.
    • (1997) Ann Surg Oncol , vol.4 , pp. 264-268
    • Han, H.M.1    Fleming, R.Y.2    Curley, S.A.3    Gallick, G.E.4
  • 24
    • 0037237066 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: Immunohistochemistry and real-time PCR analyses
    • Lark AL, Livasy CA, Calvo B, Caskey L, Moore DT, Yang X and Cance WG: Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses. Clin Cancer Res 9: 215-222, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 215-222
    • Lark, A.L.1    Livasy, C.A.2    Calvo, B.3    Caskey, L.4    Moore, D.T.5    Yang, X.6    Cance, W.G.7
  • 26
    • 0033570076 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma
    • Judson PL, He X, Cance WG and Van Le L: Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer 86: 1551-1556, 1999.
    • (1999) Cancer , vol.86 , pp. 1551-1556
    • Judson, P.L.1    He, X.2    Cance, W.G.3    Van Le, L.4
  • 27
    • 0029690892 scopus 로고    scopus 로고
    • Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer
    • Owens LV, Xu L, Dent GA, Yang X, Sturge GC, Craven RJ and Cance WG: Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. Ann Surg Oncol 3: 100-105, 1996.
    • (1996) Ann Surg Oncol , vol.3 , pp. 100-105
    • Owens, L.V.1    Xu, L.2    Dent, G.A.3    Yang, X.4    Sturge, G.C.5    Craven, R.J.6    Cance, W.G.7
  • 28
    • 0038005805 scopus 로고    scopus 로고
    • Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis
    • Beviglia L, Golubovskaya V, Xu L, Yang X, Craven RJ and Cance WG: Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis. Biochem J 373: 201-210, 2003.
    • (2003) Biochem J , vol.373 , pp. 201-210
    • Beviglia, L.1    Golubovskaya, V.2    Xu, L.3    Yang, X.4    Craven, R.J.5    Cance, W.G.6
  • 30
    • 0029741102 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
    • Gilmore AP and Romer LH: Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol Biol Cell 7: 1209-1224, 1996.
    • (1996) Mol Biol Cell , vol.7 , pp. 1209-1224
    • Gilmore, A.P.1    Romer, L.H.2


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