Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion

Journal of Trauma - Injury, Infection and Critical Care

Volumn 58, Issue 3, 2005, Pages 455-461

  Sato, Norio ^a   Moore, Frederick A ^a   Smith, Marshall A ^a   Zou, Lei ^a   Moore Olufemi, Stacey ^a   Schultz, Stanley G ^a   Kozar, Rosemary A ^a,b   Bulger, Eileen ^c   Cooney, Robert ^c  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c NONE

Author keywords

Activator protein 1 (AP 1); c jun; Immune enhancing enteral diets; Ischemia reperfusion; Nuclear factor B (NF B)

Indexed keywords

ARGININE; GLUTAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENTERIC FEEDING; GEL MOBILITY SHIFT ASSAY; INTESTINE ISCHEMIA; JEJUNUM; LAPAROTOMY; MALE; NONHUMAN; OSMOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SUPERIOR MESENTERIC ARTERY OBSTRUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ARGININE; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENTERAL NUTRITION; GLUTAMINE; IMMUNITY, MUCOSAL; IMMUNOLOGIC FACTORS; INFLAMMATION; JEJUNUM; MALE; MESENTERIC ARTERY, SUPERIOR; MESENTERIC VASCULAR OCCLUSION; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PATIENT SELECTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RISK FACTORS; TIME FACTORS; TRANSCRIPTION FACTOR AP-1;

EID: 14944371358     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TA.0000153937.04932.59     Document Type: Article

References (39)

1. Hassoun HH, Mercer DW, Moody FG, Weisbrodt NW, Moore FA. Postinjury multiple organ failure: the role of the gut. Shock. 2001;15:1-10.
2. Brown RO, Hunt H, Mowatt-Larssen CA, et al. Comparison of specialized and standard enteral formulas in trauma patients. Pharmacotherapy. 1994;14:314-320.
3. Moore FA, Moore EE, Kudsk KA, et al. Clinical benefits of an immune enhancing diet for early postinjury enteral feeding. J Trauma. 1994;37:607-615.
4. Kudsk KA, Minard G, Croce MA, et al. A randomized trial of isonitrogenous diets following severe trauma: an immune-enhancing diet reduces septic complications. Ann Surg. 1996;224:531-543.
5. Weimann A, Bastian L, Bischoff WE. et al. Influence of arginine, omega-3-fatty acids and nucleotide-supplemented enteral support on systemic inflammatory response syndrome and multiple organ failure in patients after severe trauma. Nutrition. 1998;14:165-172.
6. Dent DL, Heyland DK, Levy H, et al. Immunonutrition may increase mortality in critically ill patients with pneumonia: results of a randomized trial. Crit Care Med. 2003;30:A17.
7. Heyland DK, Samis A. Does immunonutriton in patients with sepsis do more harm than good? Intensive Care Med. 2003;29:669-671.
8. Kozar RA, Schultz SG, Verner-Cole E, et al. Enteral arginine, an immune enhancing agent, impairs gut barrier function following mesenteric ischemia/ reperfusion. J Trauma. 2004;56:463.
9. Kozar RA, Schultz SG, Bick RJ, Poindexter RJ, DeSoignie R, Moore FA. Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats. Shock. 2004;21:433-437.
10. Kozar RA, Schultz SG, Hassoun HT, et al. The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats. Gastroenterology. 2002;123:810-816.
11. Kozar RA, Sen H, Hassoun HT, DeSoignie R, Moore FA. Specific enteral nutrients alter mucosal blood flow during gut ischemia/reperfusion. JPEN J Parenter Enteral Nutr. 2002;26:226-229.
12. Hassoun JT, Zou L, Moore FA, Kozar RA, Weisbrodt NW, Kone BC. α-Melanocyte stimulating hormone protects against mesenteric ischemia-reperfusion injury. Am J Physiol. 2002;282:G1059-G1068.
13. Deryckere F, Gannon FA. One hour minipreparation technique for extraction of DNA-binding proteins from animal tissues. Biotechniques. 1994;16:405.
14. Moore EE, Jones TN. Benefits of immediate jejunal feeding after major abdominal trauma. J Trauma. 1986;26:874-881.
15. Moore FA, Moore EE, Jones TN. TEN versus TPN following major abdominal trauma reduced septic morbidity; J Trauma. 1989;29:916-922.
16. Kudsk KA, Croce MA, Fabian TC, et al. Enteral versus parenteral feeding: effects on septic morbidity following blunt and penetrating trauma. Ann Surg. 1992;215:503-511.
17. Moore FA, Feliciano DV, Andrassy RJ, et al. Early enteral feeding, compared with parenteral, reduces postoperative septic complications: the results of a meta-analysis. Ann Surg. 1992;216:62-69.
18. Suchner U, Heyland DK, Peter K. Immune-modulatory actions of arginine in the critically ill. Br J Surg. 2002;87:121-132.
19. Heyland DK, Novak F, Drover JW, et al. Should immunonutrition become routine in the critically ill patient? JAMA. 2001;286:944-953.
20. Houdijk APJ, Rijnsburger ER, Jansen J, et al. Randomized trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma. Lancet. 1998;352:772-776.
21. Garrel D, Patenaude J, Nedelec B, et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial. Crit Care Med. 2003;31:2444-2449.
22. Wischmeyer PE, Lynch J, Liedel J, Wolfson R, Riehm J, Gottlieg L. Glutamine administration reduces gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control. Crit Care Med. 2001;29:2075-2080.
23. Mendez C, Jurkovich GJ, Garcia I, Davis D, Parker A, Maier RV. Effects of an immune-enhancing diet in critically injured patients. J Trauma. 1997;42:933-941.
24. Bertolini G, Iapichino G, Radrizzani D, et al. Early enteral immunonutrition in patients with severe sepsis: results of an interim analysis of a randomized multicentre clinical trial. Intensive Care Med. 2003;29:834-840.
25. Heys SD, Walker LG, Smith I, Eremin O. Enteral nutrition supplementation with key nutrients in patients with critical illness and cancer. Ann Surg. 1999;229:467-477.
26. Beale RJ, Bryg DJ, Bihari DJ. Immunonutrition in the critically ill: a systematic review of clinical outcome. Crit Care Med. 1999;27:2799-2805.
27. Kozar RA, McQuiggan MM, Moore EE, Kudsk K, Jurkovich G, Moore FA. Postinjury enteral tolerance is reliably achieved by a standardized protocol. J Surg Res. 2002;104:70-75.
28. Kozar RA, Schultz SG, Hassoun HT, DeSoignie R, Moore FA. Intraluminal nutrients alter gut permeability following gut ischemia/ reperfusion. Shock. 2001;15(suppl):65.
29. Fukatsu MD, Ueno C, Nagayoshi H, et al. Effects of L-arginine infusion during ischemia on gut perfusion, oxygen tension, and circulating myeloid cell activation in murine gut ischemia/ reperfusion model. JPEN J Parenter Enteral Nutr. 2004;28:224-231.
30. Kone BC. Nitric oxide in renal health and disease. Am J Kidney Dis. 1997;30:311-313.
31. Van Buren G, Hassoun HT, Moore FA, et al. The effect of gut ischemia/reperfusion on ileal muscle contractility. FASEB J. 2001;15:A823.
32. Fan C, Zwacka F, Englehardt J. Therapeutic approaches for ischemia/reperfusion injury in the liver. J Mol Med. 1999;77:577-596.
33. Szabo C, Billiar TR. Novel roles of nitric oxide in hemorrhagic shock. Shock. 1999;12:1-9.
34. Yeh K, Yeh M, Glass J, Granger N. Rapid activation of NF-kB and AP-1 and target gene expression in postischemic rat intestine. Gastroenterology. 2000;118:525-534.
35. Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potential biological function. EMBO J. 1993;12:3879-3891.
36. Whitmarsh AJ, Davis RJ. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med. 1996;74:589-607.
37. Gaur U, Aggarwal B. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol. 2003;66:1403-1408.
38. Fan H, Peck OM, Tempel GE, Halushka PV, Cook JA. Toll-like receptor 4 coupled G protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NKκB activation. Shock. 2004;22:57-62.
39. Gertzberg N, Clements R, Jaspers I, et al. Tumor necrosis factor-x-induced activating protein-1 activity is modulated by nitric oxide-mediated protein kinase G activation. Am J Respir Cell Mol Biol. 2000;22:105-115.