Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors

Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2000, Pages 1215-1222

  Tamiz, Amir P ^a   Zhang, Jianrong ^a   Flippen Anderson, Judith L ^c   Zhang, Mei ^b   Johnson, Kenneth M ^b   Deschaux, Olivier ^a   Tella, Srihari ^a   Kozikowski, Alan P ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c NAVAL RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4BETA (2 NAPHTHYL)PIPERIDINE 3BETA CARBOXYLIC ACID METHYL ESTER; AMFEBUTAMONE; AMOXAPINE; DOPAMINE UPTAKE INHIBITOR; FLUOXETINE; PAROXETINE; ROXINDOLE; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; RAT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; BRAIN; CARRIER PROTEINS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MODELS, MOLECULAR; MOTOR ACTIVITY; NERVE ENDINGS; NERVE TISSUE PROTEINS; NOREPINEPHRINE; PIPERIDINES; RATS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; STEREOISOMERISM; STEREOTYPED BEHAVIOR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034704805     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9905561     Document Type: Article

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