LMP-1, a LIM-domain protein, mediates BMP-6 effects on bone formation

Endocrinology

Volumn 139, Issue 12, 1998, Pages 5125-5134

  Boden, Scott D ^a,c   Liu, Yunshan ^a   Hair, Gregory A ^a   Helms, Jill A ^b   Hu, Diane ^b   Racine, Michele ^a   Nanes, Mark S ^a   Titus, Louisa ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 6; GLUCOCORTICOID; LIMB MINERALIZATION PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CHO CELL; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT;

EID: 0031755753     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.12.6392     Document Type: Article

References (26)

1. Hogan BLM 1996 Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10:1580-1594
2. Kingsley DM 1994 What do BMPs do in mammals? Clues from the mouse short-ear mutation. Trends Genet 10:16-21
3. Boden SD, McCuaig K, Hair G, Racine M, Titus L, Wozney JM, Nanes MS 1996 Differential effects and glucocorticoid potentiation of bone morphogenetic protein action during rat osteoblast differentiation in vitro. Endocrinology 137:3401-3407
4. Boden SD, Hair G, Titus L, Racine M, McCuaig K, Wozney JM, Nanes MS 1997 Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by BMP-6. Endocrinology 138:2920-2928
5. Way JC, Chalfie M 1988 Mec-3, a homeobox-containing gene that specifies the differentiation of the touch receptor neurons in C. elegans. Cell 54:5-16
6. Karlsson O, Thor S, Norberg T, Ohlsson H, Edlund T 1990 Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeodomain and a Cys-His domain. Nature 344:879-882
7. Freyd G, Kim SK, Horvitz HR 1990 Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II. Nature 344:876-879
8. Nanes MS, Rubin J, Titus L, Hendy GN, Catherwood BD 1990 α-Interferon inhibits 1,25-Dihydroxyvitamin D3 stimulated synthesis of bone gla protein in rat osteosarcoma cells by a pretranslational mechanism. Endocrinology 127:588-594
9. Towbin H, Staehelin T, Gordon J 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedures and some applications. Proc Natl Acad Sci 76:4350-4354
10. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 7-19
11. Dawid IB, Toyama R, Taira M 1995 LIM domain proteins. C R Acad Sci Paris 318:295-306
12. Sadler I, Crawford AW, Michelsen JW, Beckerle MC 1992 Zyxin and cCRP: Two interactive LIM domain proteins associated with the cytoskeleton. J Cell Biol 119:1573-1587
13. Dawid IB, Breen JJ, Toyama R 1998 LIM domains: multiple roles as adapters and functional modifiers in protein interactions. Trends Genet 14:156-162
14. Wang M, Drucker DJ 1994 The LIM domain homeobox gene isl-1 Conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage. Endocrinology 134:1416-1422
15. Wu R, Durick K, Songyang Z, Cantley LC, Taylor SS, Gill GN 1996 Specificity of LIM domain interactions with receptor tyrosine kinases. J Biol Chem 271:15934-15941
16. Wu R, Gill GN 1994 LIM domain recognition of a tyrosine-containing tight turn. J Biol Chem 269:25085-25090
17. Kuroda S, Tokunaga C, Kiyohara Y, Higuchi O, Konishi H, Mizuno K, Gill GN, Kikkawa U 1996 Protein-protein interaction of zinc finger LIM domains with protein kinase C. J Biol Chem 271:31029-31032
18. Lyons KM, Pelton RW, Hogan BLM 1989 Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-β like genes coordinately regulate aspects of embryonic development. Genes Dev 3:1657-1668
19. Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB 1990 Factors that promote progressive development of the osteoblast phenotype in cultured rat calvarial cells. J Cell Physiol 143:213-221
20. Bellows CG, Aubin JE, Heersche JNM, Antosz ME 1986 Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int 38:143-154
21. Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GWH, Beddington RSP, Mundlos S, Olsen BR, Selby PB, Owen MJ 1997 Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89:765-771
22. Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G 1997 Osf2/Cbfa1:A transcriptional activator of osteoblast differentiation. Cell 89:747-754
23. Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao Y, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T 1997 Targeted disruption of cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764
24. Morone MA, Boden SD, Martin G, Hair G, Titus L 1998 Gene expression during autograft posterolateral lumbar spine fusion. Clin Orthop
25. Wang EA, Rosen V, D'Alessandro JS, Bauduy M, Cordes P, Harada T, Israel DI, Hewick RM, Kerns KM, LaPan P, Luxenberg DP, McQuaid D, Moutsatsos IK, Nove J, Wozney JM 1990 Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci 87:2220-2224
26. Schimandle JH, Boden SD, Hutton WC 1995 Experimental spinal fusion with recombinant human bone morphogenetic protein-2 (rhBMP-2). Spine 20:1326-1337