Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death

Journal of Cerebral Blood Flow and Metabolism

Volumn 25, Issue 3, 2005, Pages 358-370

  Aoyama, Koji ^a   Burns, David M ^a   Suh, Sang Won ^a   Garnier, Philippe ^a   Matsumori, Yasuhiko ^a   Shiina, Hiroaki ^a   Swanson, Raymond A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antisense; Endoplasmic reticulum; Glia; GRP 78; Ire1 ; Ischemia

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE PHOSPHORODIAMIDATE MORPHOLINOOLIGODEOXYNUCLEOTIDE; CASPASE 12; CASPASE 3; CHAPERONE; CYCLOHEXIMIDE; GLUCOSE REGULATED PROTEIN 78; MESSENGER RNA; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN TISSUE; CELL NUCLEUS; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DISSOCIATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; STRESS;

ACIDOSIS; ANIMALS; ASTROCYTES; CASPASE 12; CASPASE 3; CASPASES; CELL DEATH; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEAT-SHOCK PROTEINS; HYDROGEN-ION CONCENTRATION; MICE; MOLECULAR CHAPERONES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RATS; RNA, MESSENGER;

EID: 14644412870     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600043     Document Type: Article

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