β-Amyloid (Aβ) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation

Molecular and Cellular Neuroscience

Volumn 28, Issue 3, 2005, Pages 496-508

  Kranenburg, Onno ^a   Bouma, Barend ^a   Gent, Yoony Y J ^a   Aarsman, Colinda J ^a   Kayed, Rakez ^b   Posthuma, George ^a   Schiks, Bettina ^a   Voest, Emile E ^a   Gebbink, Martijn F B G ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CARBOXYPEPTIDASE B; LYSINE; OLIGOMER; PLASMIN; TISSUE PLASMINOGEN ACTIVATOR; PEPTIDE FRAGMENT; PLASMINOGEN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; MOUSE; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; OLIGOMERIZATION; PATHOPHYSIOLOGY; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; ALZHEIMER DISEASE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; METABOLISM; NERVE CELL; NEUROBLASTOMA; PATHOLOGY; PHYSIOLOGY; PROTEIN BINDING; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CARBOXYPEPTIDASE B; CELL ADHESION; CELL SURVIVAL; MICE; NEUROBLASTOMA; NEURONS; PEPTIDE FRAGMENTS; PLASMIN; PLASMINOGEN; PROTEIN BINDING; SENILE PLAQUES; TISSUE PLASMINOGEN ACTIVATOR; TUMOR CELLS, CULTURED;

EID: 14644407485     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2004.11.001     Document Type: Article

References (59)

1. D. Baranes, D. Lederfein, Y.Y. Huang, M. Chen, C.H. Bailey, and E.R. Kandel Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway Neuron 21 1998 813 825
2. E.M. Blanc, M. Toborek, R.J. Mark, B. Hennig, and M.P. Mattson Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells J. Neurochem. 68 1997 1870 1881
3. B. Bouma, L.M. Kroon-Batenburg, Y.P. Wu, B. Brunjes, G. Posthuma, O. Kranenburg, P.G. de Groot, E.E. Voest, and M.F. Gebbink Glycation induces formation of amyloid cross-beta structure in albumin J. Biol. Chem. 278 2003 41810 41819
4. M. Bucciantini, E. Giannoni, F. Chiti, F. Baroni, L. Formigli, J. Zurdo, N. Taddei, G. Ramponi, C.M. Dobson, and M. Stefani Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases Nature 416 2002 507 511
5. S.M. Cardoso, S. Santos, R.H. Swerdlow, and C.R. Oliveira Functional mitochondria are required for amyloid beta-mediated neurotoxicity FASEB J. 15 2001 1439 1441
6. J.A. Carson, and A.J. Turner Beta-Amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases? J. Neurochem. 81 2002 1 8
7. B. Caughey, and P.T. Lansbury Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders Annu. Rev. Neurosci. 26 2003 267 298
8. Z.L. Chen, and S. Strickland Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin Cell 91 1997 917 925
9. Z.L. Chen, J.A. Indyk, and S. Strickland The hippocampal laminin matrix is dynamic and critical for neuronal survival Mol. Biol. Cell 14 2003 2665 2676
10. A. Copani, J.Y. Koh, and C.W. Cotman Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation NeuroReport 2 1991 763 765
11. C. Exley, and O.V. Korchazhkina Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures NeuroReport 12 2001 2967 2970
12. V. Fleury, S. Loyau, H.R. Lijnen, W. Nieuwenhuizen, and E. Angles-Cano Molecular assembly of plasminogen and tissue-type plasminogen activator on an evolving fibrin surface Eur. J. Biochem. 216 1993 549 556
13. A. Gualandris, T.E. Jones, S. Strickland, and S.E. Tsirka Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator J. Neurosci. 16 1996 2220 2225
14. Y.Y. Huang, M.E. Bach, H.P. Lipp, M. Zhuo, D.P. Wolfer, R.D. Hawkins, L. Schoonjans, E.R. Kandel, J.M. Godfraind, R. Mulligan, D. Collen, and P. Carmeliet Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways Proc. Natl. Acad. Sci. U. S. A. 93 1996 8699 8704
15. N. Iwata, S. Tsubuki, Y. Takaki, K. Watanabe, M. Sekiguchi, E. Hosoki, M. Kawashima-Morishima, H.J. Lee, E. Hama, Y. Sekine-Aizawa, and T.C. Saido Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition Nat. Med. 6 2000 143 150
16. N. Iwata, S. Tsubuki, Y. Takaki, K. Shirotani, B. Lu, N.P. Gerard, C. Gerard, E. Hama, H.J. Lee, and T.C. Saido Metabolic regulation of brain Abeta by neprilysin Science 292 2001 1550 1552
17. R.N. Kalaria, and P. Hedera Differential degeneration of the cerebral microvasculature in Alzheimer's disease NeuroReport 6 1995 477 480
18. R. Kayed, E. Head, J.L. Thompson, T.M. McIntire, S.C. Milton, C.W. Cotman, and C.G. Glabe Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 2003 486 489
19. H.J. Kim, S.C. Chae, D.K. Lee, B. Chromy, S.C. Lee, Y.C. Park, W.L. Klein, G.A. Krafft, and S.T. Hong Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein FASEB J. 17 2003 118 120
20. I.B. Kingston, M.J. Castro, and S. Anderson In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid beta-peptide analogues Nat. Med. 1 1995 138 142
21. O. Kranenburg, V. Scharnhorst, A.J. Van der Eb, and A. Zantema Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells J. Cell Biol. 131 1995 227 234
22. O. Kranenburg, B. Bouma, L.M. Kroon-Batenburg, A. Reijerkerk, Y.P. Wu, E.E. Voest, and M.F. Gebbink Tissue-type plasminogen activator is a multiligand cross-beta structure receptor Curr. Biol. 12 2002 1833 1839
23. M.D. Ledesma, J.S. Da Silva, K. Crassaerts, A. Delacourte, B. De Strooper, and C.G. Dotti Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains EMBO Rep. 1 2000 530 535
24. R. Madani, S. Hulo, N. Toni, H. Madani, T. Steimer, D. Muller, and J.D. Vassalli Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice EMBO J. 18 1999 3007 3012
25. E. Masliah, M. Mallory, L. Hansen, M. Alford, T. Albright, R. DeTeresa, R. Terry, J. Baudier, and T. Saitoh Patterns of aberrant sprouting in Alzheimer's disease Neuron 6 1991 729 739
26. A. Matsumoto, K. Itoh, and R. Matsumoto A novel carboxypeptidase B that processes native beta-Amyloid precursor protein is present in human hippocampus Eur. J. Neurosci. 12 2000 227 238
27. A. Matsumoto, K. Itoh, T. Seki, K. Motozaki, and S. Matsuyama Human brain carboxypeptidase B, which cleaves beta-Amyloid peptides in vitro, is expressed in the endoplasmic reticulum of neurons Eur. J. Neurosci. 13 2001 1653 1657
28. W. Meier-Ruge, and C. Bertoni-Freddari The significance of glucose turnover in the brain in the pathogenetic mechanisms of Alzheimer's disease Rev. Neurosci. 7 1996 1 19
29. O. Meilhac, B. Ho-Tin-Noe, X. Houard, M. Philippe, J.B. Michel, and E. Angles-Cano Pericellular plasmin induces smooth muscle cell anoikis FASEB J. 17 2003 1301 1303
30. J.P. Melchor, R. Pawlak, and S. Strickland The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration J. Neurosci. 23 2003 8867 8871
31. N. Nagai, M. De Mol, H.R. Lijnen, P. Carmeliet, and D. Collen Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice Circulation 99 1999 2440 2444
32. Y. Nakagami, K. Abe, N. Nishiyama, and N. Matsuki Laminin degradation by plasmin regulates long-term potentiation J. Neurosci. 20 2000 2003 2010
33. M. Nesheim, J. Walker, W. Wang, M. Boffa, A. Horrevoets, and L. Bajzar Modulation of fibrin cofactor activity in plasminogen activation Ann. N. Y. Acad. Sci. 936 2001 247 260
34. W. Nieuwenhuizen Fibrin-mediated plasminogen activation Ann. N. Y. Acad. Sci. 936 2001 237 246
35. W. Nieuwenhuizen, M. Voskuilen, A. Vermond, B. Hoegee-de Nobel, and D.W. Traas The influence of fibrin(ogen) fragments on the kinetic parameters of the tissue-type plasminogen-activator-mediated activation of different forms of plasminogen Eur. J. Biochem. 174 1988 163 169
36. R.J. Parmer, M. Mahata, S. Mahata, M.T. Sebald, D.T. O'Connor, and L.A. Miles Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of t-PA J. Biol. Chem. 272 1997 1976 1982
37. C.J. Pike, D. Burdick, A.J. Walencewicz, C.G. Glabe, and C.W. Cotman Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state J. Neurosci. 13 1993 1676 1687
38. J.F. Poduslo, G.L. Curran, J.J. Haggard, A.L. Biere, and D.J. Selkoe Permeability and residual plasma volume of human, Dutch variant, and rat amyloid beta-protein 1-40 at the blood-brain barrier Neurobiol. Dis. 4 1997 27 34
39. J.F. Poduslo, G.L. Curran, B. Sanyal, and D.J. Selkoe Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier Neurobiol. Dis. 6 1999 190 199
40. A. Reijerkerk, L.O. Mosnier, O. Kranenburg, B.N. Bouma, P. Carmeliet, T. Drixler, J.C. Meijers, E.E. Voest, and M.F. Gebbink Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system Mol. Cancer Res. 1 2003 561 568
41. K.C. Robbins, L. Summaria, B. Hsieh, and R.J. Shah The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin J. Biol. Chem. 242 1967 2333 2342
42. F.J. Salles, and S. Strickland Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus J. Neurosci. 22 2002 2125 2134
43. N.W. Seeds, M.E. Basham, and S.P. Haffke Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene Proc. Natl. Acad. Sci. U. S. A. 96 1999 14118 14123
44. D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiol. Rev. 81 2001 741 766
45. D.J. Selkoe Alzheimer disease: mechanistic understanding predicts novel therapies Ann. Intern. Med. 140 2004 627 638
46. M. Shibata, S. Yamada, S.R. Kumar, M. Calero, J. Bading, B. Frangione, D.M. Holtzman, C.A. Miller, D.K. Strickland, J. Ghiso, and B.V. Zlokovic Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier J. Clin. Invest. 106 2000 1489 1499
47. S.E. Tsirka, A. Gualandris, D.G. Amaral, and S. Strickland Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator Nature 377 1995 340 344
48. S.E. Tsirka, T.H. Bugge, J.L. Degen, and S. Strickland Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin Proc. Natl. Acad. Sci. U. S. A. 94 1997 9779 9781
49. S.E. Tsirka, A.D. Rogove, T.H. Bugge, J.L. Degen, and S. Strickland An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus J. Neurosci. 17 1997 543 552
50. H.M. Tucker, M. Kihiko-Ehmann, S. Wright, R.E. Rydel, and S. Estus Tissue plasminogen activator requires plasminogen to modulate amyloid-beta neurotoxicity and deposition J. Neurochem. 75 2000 2172 2177
51. H.M. Tucker, M. Kihiko, J.N. Caldwell, S. Wright, T. Kawarabayashi, D. Price, D. Walker, S. Scheff, J.P. McGillis, R.E. Rydel, and S. Estus The plasmin system is induced by and degrades amyloid-beta aggregates J. Neurosci. 20 2000 3937 3946
52. W.E. Van Nostrand, and M. Porter Plasmin cleavage of the amyloid beta-protein: alteration of secondary structure and stimulation of tissue plasminogen activator activity Biochemistry 38 1999 11570 11576
53. W.E. Van Nostrand, J. Melchor, M. Wagner, and J. Davis Cerebrovascular smooth muscle cell surface fibrillar A beta. Alteration of the proteolytic environment in the cerebral vessel wall Ann. N. Y. Acad. Sci. 903 2000 89 96
54. A.J. van Zonneveld, H. Veerman, and H. Pannekoek On the interaction of the finger and the kringle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by epsilon-amino caproic acid J. Biol. Chem. 261 1986 14214 14218
55. S. Ventura, V. Villegas, J. Sterner, J. Larson, J. Vendrell, C.L. Hershberger, and F.X. Aviles Mapping the pro-region of carboxypeptidase B by protein engineering. Cloning, overexpression, and mutagenesis of the porcine proenzyme J. Biol. Chem. 274 1999 19925 19933
56. D.M. Walsh, and D.J. Selkoe Deciphering the molecular basis of memory failure in Alzheimer's disease Neuron 44 2004 181 193
57. D.M. Walsh, and D.J. Selkoe Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration Protein Pept. Lett. 11 2004 213 228
58. Y.F. Wang, S.E. Tsirka, S. Strickland, P.E. Stieg, S.G. Soriano, and S.A. Lipton Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice Nat. Med. 4 1998 228 231
59. S. Wnendt, I. Wetzels, and W.A. Gunzler Amyloid beta peptides stimulate tissue-type plasminogen activator but not recombinant prourokinase Thromb. Res. 85 1997 217 224