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Volumn 12, Issue 2, 2005, Pages 237-247

A neoceptor approach to unraveling microscopic interactions between the human A2A adenosine receptor and its agonists

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EID: 14144249916     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.12.010     Document Type: Article
Times cited : (46)

References (40)
  • 1
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • B.B. Fredholm, A.P. IJzerman, K.A. Jacobson, K-N. Klotz, and J. Linden International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors Pharmacol. Rev. 53 2001 527 552
    • (2001) Pharmacol. Rev. , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.-N.4    Linden, J.5
  • 5
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • A. Ohta, and M. Sitkovsky Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage Nature 414 2001 916 920
    • (2001) Nature , vol.414 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 11
    • 0033939473 scopus 로고    scopus 로고
    • Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D
    • M. Parsons, L. Young, J.-E. Lee, K.A. Jacobson, and B.T. Liang Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D FASEB J. 14 2000 1423 1431
    • (2000) FASEB J. , vol.14 , pp. 1423-1431
    • Parsons, M.1    Young, L.2    Lee, J.-E.3    Jacobson, K.A.4    Liang, B.T.5
  • 13
    • 0037242885 scopus 로고    scopus 로고
    • Syntheses of purines bearing carbon substituents in positions 2, 6 or 8 by metal- or organometal-mediated C C bond-forming reactions
    • M. Hocek Syntheses of purines bearing carbon substituents in positions 2, 6 or 8 by metal- or organometal-mediated C C bond-forming reactions Eur. J. Org. Chem. 2003 245 254
    • (2003) Eur. J. Org. Chem. , pp. 245-254
    • Hocek, M.1
  • 16
    • 0032008085 scopus 로고    scopus 로고
    • Engineering Src family protein kinases with unnatural nucleotide specificity
    • Y. Liu, K. Shah, F. Yang, L. Witucki, and K.M. Shokat Engineering Src family protein kinases with unnatural nucleotide specificity Chem. Biol. 5 1998 91 101
    • (1998) Chem. Biol. , vol.5 , pp. 91-101
    • Liu, Y.1    Shah, K.2    Yang, F.3    Witucki, L.4    Shokat, K.M.5
  • 17
    • 0030943419 scopus 로고    scopus 로고
    • Cell-specific calcineurin inhibition by a modifed cyclosporin
    • P.J. Belshaw, and S.L. Schreiber Cell-specific calcineurin inhibition by a modifed cyclosporin J. Am. Chem. Soc. 119 1997 1805 1806
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 1805-1806
    • Belshaw, P.J.1    Schreiber, S.L.2
  • 18
    • 0035068096 scopus 로고    scopus 로고
    • The estrogen receptor: A structure-based approach to the design of new specific hormone-receptor combinations
    • R. Tedesco, J.A. Thomas, B.S. Katzenellenbogen, and J.A. Katzenellenbogen The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations Chem. Biol. 8 2001 277 287
    • (2001) Chem. Biol. , vol.8 , pp. 277-287
    • Tedesco, R.1    Thomas, J.A.2    Katzenellenbogen, B.S.3    Katzenellenbogen, J.A.4
  • 19
    • 0036008086 scopus 로고    scopus 로고
    • Designing selectivity and discrimination into re-engineered ligand-receptor interfaces; Beyond bumps and holes
    • J.T. Koh Designing selectivity and discrimination into re-engineered ligand-receptor interfaces; beyond bumps and holes Chem. Biol. 9 2002 17 23
    • (2002) Chem. Biol. , vol.9 , pp. 17-23
    • Koh, J.T.1
  • 20
    • 0037047423 scopus 로고    scopus 로고
    • Protein engineering of protein kinase a catalytic subunits results in the acquisition of novel inhibitor sensitivity
    • C.M. Niswender, R.W. Ishihara, L.M. Judge, C. Zhang, K.M. Shokat, and G.S. McKnight Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity J. Biol. Chem. 277 2002 28916 28922
    • (2002) J. Biol. Chem. , vol.277 , pp. 28916-28922
    • Niswender, C.M.1    Ishihara, R.W.2    Judge, L.M.3    Zhang, C.4    Shokat, K.M.5    McKnight, G.S.6
  • 23
    • 0000017231 scopus 로고
    • The reaction of dimethylchloromethylene ammonium chloride with 2′,3′,5′-tri-O-acetylinosine: A new synthesis of 6-chloro-9-(beta-D-ribofuranosyl)purine
    • J. Žemlička, and F. Šorm The reaction of dimethylchloromethylene ammonium chloride with 2′,3′,5′-tri-O- acetylinosine: a new synthesis of 6-chloro-9-(beta-D-ribofuranosyl)purine Collect. Czech. Chem. Commun. 30 1965 1880 1885
    • (1965) Collect. Czech. Chem. Commun. , vol.30 , pp. 1880-1885
    • Žemlička, J.1    Šorm, F.2
  • 24
    • 0025110788 scopus 로고
    • Approaches to isozyme-specific inhibitors. 17. Attachment of a selectivity-inducing substituent to a multisubstrate adduct. Implications for facilitated design of potent, isozyme-selective inhibitors
    • F. Kappler, and A. Hampton Approaches to isozyme-specific inhibitors. 17. Attachment of a selectivity-inducing substituent to a multisubstrate adduct. Implications for facilitated design of potent, isozyme-selective inhibitors J. Med. Chem. 33 1990 2545 2551
    • (1990) J. Med. Chem. , vol.33 , pp. 2545-2551
    • Kappler, F.1    Hampton, A.2
  • 28
    • 0034284625 scopus 로고    scopus 로고
    • 2A adenosine receptors: Involvement of Glu13 and His278 in ligand binding and sodium modulation
    • 2A adenosine receptors: involvement of Glu13 and His278 in ligand binding and sodium modulation Biochem Pharmacol. 60 2000 661 668
    • (2000) Biochem Pharmacol. , vol.60 , pp. 661-668
    • Gao, Z.-G.1    Jiang, Q.2    Jacobson, K.A.3    Ijzerman, A.P.4
  • 29
    • 0025143320 scopus 로고
    • A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid
    • C. Nordstedt, and B.B. Fredholm A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid Anal. Biochem. 189 1990 231 234
    • (1990) Anal. Biochem. , vol.189 , pp. 231-234
    • Nordstedt, C.1    Fredholm, B.B.2
  • 32
    • 0035099079 scopus 로고    scopus 로고
    • Specific organ gene transfer in vivo by regional organ perfusion with herpes viral amplicon vectors: Implications for local gene therapy
    • A.D. Brooks, B. Ng, D. Liu, M. Brownlee, M. Burt, H.J. Federoff, and Y. Fong Specific organ gene transfer in vivo by regional organ perfusion with herpes viral amplicon vectors: implications for local gene therapy Surgery 129 2001 324 334
    • (2001) Surgery , vol.129 , pp. 324-334
    • Brooks, A.D.1    Ng, B.2    Liu, D.3    Brownlee, M.4    Burt, M.5    Federoff, H.J.6    Fong, Y.7
  • 35
    • 0001242234 scopus 로고    scopus 로고
    • MMFF VII. Characterization of MMFF94, MMFF94s, and other widely available force fields for conformational energies and for intermolecular-interaction energies and geometries
    • T.A. Halgren MMFF VII. Characterization of MMFF94, MMFF94s, and other widely available force fields for conformational energies and for intermolecular-interaction energies and geometries J. Comput. Chem. 20 1999 730 748
    • (1999) J. Comput. Chem. , vol.20 , pp. 730-748
    • Halgren, T.A.1
  • 36
    • 0025390935 scopus 로고
    • MOPAC: A semiempirical molecular orbital program
    • J.J.P. Stewart MOPAC: a semiempirical molecular orbital program J. Comput. Aided Mol. Des. 4 1990 1 105
    • (1990) J. Comput. Aided Mol. Des. , vol.4 , pp. 1-105
    • Stewart, J.J.P.1
  • 37
    • 33646940952 scopus 로고
    • Numerical integration of the Cartesian equations of motion for a system with constraints: Molecular dynamics of n-alkanes
    • J.P. Ryckaert, G. Ciccotti, and H.J.C. Berendsen Numerical integration of the Cartesian equations of motion for a system with constraints: molecular dynamics of n-alkanes J. Comput. Phys. 23 1977 327 341
    • (1977) J. Comput. Phys. , vol.23 , pp. 327-341
    • Ryckaert, J.P.1    Ciccotti, G.2    Berendsen, H.J.C.3
  • 39
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 40
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction
    • Y-C. Cheng, and W.H. Prusoff Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction Biochem. Pharmacol. 22 1973 3099 3108
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
    • Cheng, Y.-C.1    Prusoff, W.H.2


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