Antiapoptotic response to induced GSH depletion: Involvement of heat shock proteins and NF-κB activation

Antioxidants and Redox Signaling

Volumn 7, Issue 3-4, 2005, Pages 446-455

  Filomeni, Giuseppe ^a   Aquilano, Katia ^a   Rotilio, Giuseppe ^a   Ciriolo, Maria R ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; BUTHIONINE SULFOXIMINE; CARBONYL DERIVATIVE; CYTOCHROME C; GLUTATHIONE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOCHONDRIAL PROTEIN; PROTEASOME; REACTIVE OXYGEN METABOLITE;

ADAPTATION; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; MONOCYTIC LEUKEMIA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; BUTHIONINE SULFOXIMINE; CYTOCHROMES C; FLAVOPROTEINS; GLUTATHIONE; HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 14044273000     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.446     Document Type: Article

References (31)

1. Adrain C and Martin SI. The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem Sci 26: 390-397, 2001.
2. Anderson CP, Tsai JM, Meek WE, Liu RM, Tang Y, Forman HJ, and Reynolds CR. Depletion of glutathione by buthionine sulfoximine is cytotoxic for human neuroblastoma cell lines via apoptosis. Exp Cell Res 246: 183-192, 1999.
3. Aquilano K, Rotilio G, and Ciriolo MR. Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS. J Neurochem 85: 1324-1335, 2003.
4. Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E, and Garrido C. Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2: 645-652, 2000.
5. Cain K, Bratton SB, and Cohen GM. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie 84: 203-214, 2002.
6. Cande C, Cohen I, Daugas E, Ravagnan L, Larochette N, Zamzami N, and Kroemer G. Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. Biochimie 84: 215-222, 2002.
7. Esposti MD. The roles of Bid. Apoptosis 1: 433-440, 2002.
8. Filomeni G, Rotilio G, and Ciriolo MR. Cell signalling and the glutathione redox system. Biochem Pharmacol 64: 1057-1064, 2002.
9. Filomeni G, Rotilio G, and Ciriolo MR. Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. FASEB J 17: 64-66, 2003.
10. Flohè L. Glutathione peroxidase: fact and fiction Ciba Found Symp 65: 95-122, 1978.
11. Franklin CC, Krejsa CM, Pierce RH, White CC, Fausto N, and Kavanagh TJ. Caspase-3-dependent cleavage of the glutamate-L-cysteine ligase catalytic subunit during apoptotic cell death. Am J Pathol 160: 1887-1894, 2002.
12. Friesen C, Kiess Y, and Debatin KM. A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells. Cell Death Differ 11 Suppl 1: S73-S85, 2004.
13. Garrido C, Gurbuxani S, Ravagnan E, and Kroemer G. Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem Biophys Res Commun 286: 433-442, 2001.
14. Ghibelli E, Coppola S, Rotilio G, Lafavia E, Maresca V, and Ciriolo MR. Non-oxidative loss of glutathione in apoptosis via GSH extrusion. Biochem Biophys Res Commun 216: 313-320, 1995.
15. Ghibelli E, Fanelli C, Rotilio G, Lafavia E, Coppola S, Colussi C, Civitareale P, and Ciriolo MR. Rescue of cells from apoptosis by inhibition of active GSH extrusion. FASEB J 12: 479-486, 1998.
16. Ghibelli E, Coppola S, Fanelli C, Rotilio G, Civitareale P, Scovassi AI, and Ciriolo MR. Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis. FASEB J 13: 2031-2036, 1999.
17. Ghosh S and Karin M. Missing pieces in the NF-κB puzzle. Cell 109: S81-S96, 2002.
18. Iverson SL and Orrenius S. The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis. Arch Biochem Biophys 423: 37-46, 2004.
19. Lee MH, Hyun DH, Marshall KA, Ellerby LM, Bredesen DE, Jenne P, and Halliwell B. Effect of overexpression of Bcl-2 on cellular oxidative damage, nitric oxide production, antioxidant defences and the proteasome. Free Radic Biol Med 31: 1550-1559, 2001.
20. Lewis J, Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L, and Liu ZG. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RLP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J Biol Chem 275: 10519-10526, 2000.
21. Lowry OH, Rosebrough NJ, Farr AL, and Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951.
22. Mattson MP and Kroemer G. Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol Med 9: 196-205, 2003.
23. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, and Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139: 271-279, 1991.
24. Parcellier A, Gurbuxani S, Schmitt E, Solary E, and Garrido C. Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways. Biochem Biophys Res Commun 304: 505-512, 2003.
25. Pirkkala L, Nykanen P, and Sistonen L. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J 15: 1118-1131, 2001.
26. Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C, and Kroemer G. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 3: 839-843, 2001.
27. Reed DJ, Babson JR, Beatty PW, Brodie AE, Ellis WW, and Potter DW. High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal Biochem 106: 55-62, 1980.
28. Rogalla T, Ehrnsperger M, Preville X, Kotlyarov A, Lutsch G, Ducasse C, Paul C, Wieske M, Arrigo AP, Buchner J, and Gaestel M. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem 274: 18947-18956, 1999.
29. Rouzer CA, Scott WA, Griffith OW, Hamill AL, and Cohn ZA. Glutathione metabolism in resting and phagocytizing peritoneal macrophages. J Biol Chem 257: 2002-2008, 1982.
30. Saleh A, Srinivasula SM, Balkir L, Robbins PD, and Alnemri ES. Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat Cell Biol 2: 476-483, 2000.
31. Thornberry NA and Lazebnik Y. Caspases: enemies within. Science 281: 1312-1316, 1998.