The antitumor drug candidate 2-(4-amino-3-methylphenyl)-5- fluorobenzothiazole induces NF-κB activity in drug-sensitive MCF-7 cells

Anti-Cancer Drugs

Volumn 16, Issue 2, 2005, Pages 137-143

  Brantley, Eileen ^a   Patel, Vyomesh ^b   Stinson, Sherman F ^a   Trapani, Valentina ^c   Hose, Curtis D ^d   Ciolino, Henry P ^a   Yeh, Grace C ^a   Gutkind, J Silvio ^b   Sausville, Edward A ^e,f   Loaiza Pérez, Andrea I ^e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d SAIC FREDERICK INC   (United States)

^e Developmental Therapeutics Program   (United States)

^f UNIVERSITY OF MARYLAND   (United States)

Author keywords

5F 203; Aryl hydrocarbon receptor; Breast cancer; Interleukin 6; NF B

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL) 5 FLUOROBENZOTHIAZOLE; AROMATIC HYDROCARBON RECEPTOR; BENZOTHIAZOLE DERIVATIVE; DIOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NSC 703786; NSC 726576; NSC 726577; NSC 726578; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA RESPONSIVE ELEMENT; DRUG STRUCTURE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENES, REPORTER; HUMANS; INTERLEUKIN-6; LUCIFERASES; NF-KAPPA B; RECEPTORS, ARYL HYDROCARBON; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIAZOLES; TRANSCRIPTION, GENETIC;

EID: 13844298869     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200502000-00004     Document Type: Article

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