메뉴 건너뛰기




Volumn 333, Issue 2, 2005, Pages 324-336

Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth

Author keywords

Cell growth; HCC; HCV NS3; JNK; MAP kinase

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NON STRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 3; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 13844265988     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2005.01.008     Document Type: Article
Times cited : (69)

References (54)
  • 1
    • 0038814247 scopus 로고    scopus 로고
    • Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: Suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1
    • S. Ahmed, A. Rahman, A. Hasnain, V.M. Goldberg, and T.M. Haqqi Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1 J. Pharmacol. Exp. Ther. 305 2003 981 988
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 981-988
    • Ahmed, S.1    Rahman, A.2    Hasnain, A.3    Goldberg, V.M.4    Haqqi, T.M.5
  • 2
    • 0024377134 scopus 로고
    • Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
    • H.J. Alter, R.H. Purcell, J.W. Shih, J.C. Melpolder, M. Houghton, Q.L. Choo, and G. Kuo Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis N. Engl. J. Med. 321 1989 1494 1500
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1494-1500
    • Alter, H.J.1    Purcell, R.H.2    Shih, J.W.3    Melpolder, J.C.4    Houghton, M.5    Choo, Q.L.6    Kuo, G.7
  • 3
    • 0024276523 scopus 로고
    • The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
    • P. Angel, K. Hattori, T. Smeal, and M. Karin The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1 Cell 55 1988 875 885
    • (1988) Cell , vol.55 , pp. 875-885
    • Angel, P.1    Hattori, K.2    Smeal, T.3    Karin, M.4
  • 5
    • 0034682264 scopus 로고    scopus 로고
    • Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation
    • A. Behrens, W. Jochum, M. Sibilia, and E.F. Wagner Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation Oncogene 19 2000 2657 2663
    • (2000) Oncogene , vol.19 , pp. 2657-2663
    • Behrens, A.1    Jochum, W.2    Sibilia, M.3    Wagner, E.F.4
  • 7
    • 0029992405 scopus 로고    scopus 로고
    • Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase
    • P. Borowski, M. Heiland, K. Oehlmann, B. Becker, L. Kornetzky, H. Feucht, and R. Laufs Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase Eur. J. Biochem. 237 1996 611 618
    • (1996) Eur. J. Biochem. , vol.237 , pp. 611-618
    • Borowski, P.1    Heiland, M.2    Oehlmann, K.3    Becker, B.4    Kornetzky, L.5    Feucht, H.6    Laufs, R.7
  • 8
    • 0032980723 scopus 로고    scopus 로고
    • The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells
    • F. Bost, R. McKay, M. Bost, O. Potapova, N.M. Dean, and D. Mercola The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells Mol. Cell. Biol. 19 1999 1938 1949
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1938-1949
    • Bost, F.1    McKay, R.2    Bost, M.3    Potapova, O.4    Dean, N.M.5    Mercola, D.6
  • 9
    • 0032546498 scopus 로고    scopus 로고
    • AP-1 and ATF-2 are constitutively activated via the JNK pathway in Theileria parva-transformed T-cells
    • C. Botteron, and D. Dobbelaere AP-1 and ATF-2 are constitutively activated via the JNK pathway in Theileria parva-transformed T-cells Biochem. Biophys. Res. Commun. 246 1998 418 421
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 418-421
    • Botteron, C.1    Dobbelaere, D.2
  • 10
    • 0031455626 scopus 로고    scopus 로고
    • Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
    • C. Caelles, J.M. Gonzalez-Sancho, and A. Munoz Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway Genes Dev. 11 1997 3351 3364
    • (1997) Genes Dev. , vol.11 , pp. 3351-3364
    • Caelles, C.1    Gonzalez-Sancho, J.M.2    Munoz, A.3
  • 11
    • 0030928381 scopus 로고    scopus 로고
    • Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East
    • R.W. Chamberlain, N. Adams, A.A. Saeed, P. Simmonds, and R.M. Elliott Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East J. Gen. Virol. 78 1997 1341 1347
    • (1997) J. Gen. Virol. , vol.78 , pp. 1341-1347
    • Chamberlain, R.W.1    Adams, N.2    Saeed, A.A.3    Simmonds, P.4    Elliott, R.M.5
  • 12
    • 0037810249 scopus 로고    scopus 로고
    • Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention
    • F. Chang, L.S. Steelman, J.T. Lee, J.G. Shelton, P.M. Navolanic, W.L. Blalock, R.A. Franklin, and J.A. McCubrey Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention Leukemia 17 2003 1263 1293
    • (2003) Leukemia , vol.17 , pp. 1263-1293
    • Chang, F.1    Steelman, L.S.2    Lee, J.T.3    Shelton, J.G.4    Navolanic, P.M.5    Blalock, W.L.6    Franklin, R.A.7    McCubrey, J.A.8
  • 13
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Q.L. Choo, G. Kuo, A.J. Weiner, L.R. Overby, D.W. Bradley, and M. Houghton Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome Science 244 1989 359 362
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 14
    • 0036058267 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces cell proliferation and activates ERK, JNK, and p38 MAP kinases together with the MAP kinase phosphatase MKP-1 in a HepG2 Tet-Off cell line
    • A. Erhardt, M. Hassan, T. Heintges, and D. Haussinger Hepatitis C virus core protein induces cell proliferation and activates ERK, JNK, and p38 MAP kinases together with the MAP kinase phosphatase MKP-1 in a HepG2 Tet-Off cell line Virology 292 2002 272 284
    • (2002) Virology , vol.292 , pp. 272-284
    • Erhardt, A.1    Hassan, M.2    Heintges, T.3    Haussinger, D.4
  • 15
    • 0030600543 scopus 로고    scopus 로고
    • Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus
    • T. Fujita, S. Ishido, S. Muramatsu, M. Itoh, and H. Hotta Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus Biochem. Biophys. Res. Commun. 229 1996 825 831
    • (1996) Biochem. Biophys. Res. Commun. , vol.229 , pp. 825-831
    • Fujita, T.1    Ishido, S.2    Muramatsu, S.3    Itoh, M.4    Hotta, H.5
  • 17
    • 0024457639 scopus 로고
    • A cis-acting mutation in the Sindbis virus junction region which affects subgenomic RNA synthesis
    • A. Grakoui, R. Levis, R. Raju, H.V. Huang, and C.M. Rice A cis-acting mutation in the Sindbis virus junction region which affects subgenomic RNA synthesis J. Virol. 63 1989 5216 5227
    • (1989) J. Virol. , vol.63 , pp. 5216-5227
    • Grakoui, A.1    Levis, R.2    Raju, R.3    Huang, H.V.4    Rice, C.M.5
  • 18
    • 0032953984 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells
    • Y.L. Guo, B. Kang, L.J. Yang, and J.R. Williamson Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells Am. J. Physiol. 276 1999 390 397
    • (1999) Am. J. Physiol. , vol.276 , pp. 390-397
    • Guo, Y.L.1    Kang, B.2    Yang, L.J.3    Williamson, J.R.4
  • 20
    • 0034931503 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
    • Z. Han, D.L. Boyle, L. Chang, B. Bennett, M. Karin, L. Yang, A.M. Manning, and G.S. Firestein c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis J. Clin. Invest. 108 2001 73 81
    • (2001) J. Clin. Invest. , vol.108 , pp. 73-81
    • Han, Z.1    Boyle, D.L.2    Chang, L.3    Bennett, B.4    Karin, M.5    Yang, L.6    Manning, A.M.7    Firestein, G.S.8
  • 21
    • 4644276886 scopus 로고    scopus 로고
    • Activation of RB/E2F signalling pathway is required for the modulation of hepatitis C virus (HCV) core protein-induced cell growth in liver and non-liver cells
    • M. Hassan, H. Ghozlan, and O. Abdel-kader Activation of RB/E2F signalling pathway is required for the modulation of hepatitis C virus (HCV) core protein-induced cell growth in liver and non-liver cells Cell Signalling 16 2004 1375 1385
    • (2004) Cell Signalling , vol.16 , pp. 1375-1385
    • Hassan, M.1    Ghozlan, H.2    Abdel-Kader, O.3
  • 22
    • 0037348046 scopus 로고    scopus 로고
    • Hepatocyte transformation and tumour development induced by hepatitis C virus NS3 c-terminal deleted protein
    • Q.Q. He, R.X. Cheng, Y. Sun, D.Y. Feng, Z.C. Chen, and H. Zheng Hepatocyte transformation and tumour development induced by hepatitis C virus NS3 c-terminal deleted protein World J. Gastroenterol. 9 2003 474 478
    • (2003) World J. Gastroenterol. , vol.9 , pp. 474-478
    • He, Q.Q.1    Cheng, R.X.2    Sun, Y.3    Feng, D.Y.4    Chen, Z.C.5    Zheng, H.6
  • 23
    • 0029950090 scopus 로고    scopus 로고
    • Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system
    • Z. Hong, E. Ferrari, J. Wright-Minogue, R. Chase, C. Risano, G. Seelig, C.G. Lee, and A.D. Kwong Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system J. Virol. 70 1996 4261 4428
    • (1996) J. Virol. , vol.70 , pp. 4261-4428
    • Hong, Z.1    Ferrari, E.2    Wright-Minogue, J.3    Chase, R.4    Risano, C.5    Seelig, G.6    Lee, C.G.7    Kwong, A.D.8
  • 24
    • 0028693067 scopus 로고
    • 1001 protein kinases redux-towards 2000
    • T. Hunter 1001 protein kinases redux-towards 2000 Semin. Cell Biol. 5 1994 367 376
    • (1994) Semin. Cell Biol. , vol.5 , pp. 367-376
    • Hunter, T.1
  • 26
  • 27
    • 0028817781 scopus 로고
    • C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
    • D.W. Kim, Y. Gwack, J.H. Han, and J. Choe C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity Biochem. Biophys. Res. Commun. 215 1995 160 166
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 160-166
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 28
    • 0034852454 scopus 로고    scopus 로고
    • P53-dependent transcriptional repression of p21 (waf 1) by hepatitis C virus NS3
    • H.J. Kwun, E.Y. Jung, J.Y. Ahn, M.N. Lee, and K.L. Jang P53-dependent transcriptional repression of p21 (waf 1) by hepatitis C virus NS3 J. Gen. Virol. 82 2001 2235 2241
    • (2001) J. Gen. Virol. , vol.82 , pp. 2235-2241
    • Kwun, H.J.1    Jung, E.Y.2    Ahn, J.Y.3    Lee, M.N.4    Jang, K.L.5
  • 30
    • 0034967538 scopus 로고    scopus 로고
    • Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells
    • S. Leppa, M. Eriksson, R. Saffrich, W. Ansorge, and D. Bohmann Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells Mol. Cell. Biol. 21 2001 4369 4378
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4369-4378
    • Leppa, S.1    Eriksson, M.2    Saffrich, R.3    Ansorge, W.4    Bohmann, D.5
  • 31
    • 2142710154 scopus 로고    scopus 로고
    • Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice
    • A. Lgssiar, M. Hassan, P. Schott-ohly, N. Friesen, F. Nicolitti, W.L. Trepicchio, and H. Gleichmann Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice Exp. Biol. Med. 229 2004 425 436
    • (2004) Exp. Biol. Med. , vol.229 , pp. 425-436
    • Lgssiar, A.1    Hassan, M.2    Schott-Ohly, P.3    Friesen, N.4    Nicolitti, F.5    Trepicchio, W.L.6    Gleichmann, H.7
  • 32
    • 0141723789 scopus 로고    scopus 로고
    • Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway
    • S. Lin, J.J. Li, M. Fujii, and D.X. Hou Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway Int. J. Oncol. 22 2003 829 833
    • (2003) Int. J. Oncol. , vol.22 , pp. 829-833
    • Lin, S.1    Li, J.J.2    Fujii, M.3    Hou, D.X.4
  • 33
    • 0035341268 scopus 로고    scopus 로고
    • How protein kinase C activation protects nerve cells from oxidative stress-induced cell death
    • P. Maher How protein kinase C activation protects nerve cells from oxidative stress-induced cell death J. Neurosci. 21 2001 2929 2938
    • (2001) J. Neurosci. , vol.21 , pp. 2929-2938
    • Maher, P.1
  • 35
    • 0037477332 scopus 로고    scopus 로고
    • Identification of hepatitis C virus (HCV) subtype 1b strains that are highly, or only weakly, associated with hepatocellular carcinoma on the basis of the secondary structure of an amino-terminal portion of the HCV NS3 protein
    • S. Ogata, R.H. Florese, M. Nagano-Fujii, R. Hidajat, L. Deng, Y. Ku, S. Yoon, T. Saito, S. Kawata, and H. Hotta Identification of hepatitis C virus (HCV) subtype 1b strains that are highly, or only weakly, associated with hepatocellular carcinoma on the basis of the secondary structure of an amino-terminal portion of the HCV NS3 protein J. Clin. Microbiol. 41 2003 2835 2841
    • (2003) J. Clin. Microbiol. , vol.41 , pp. 2835-2841
    • Ogata, S.1    Florese, R.H.2    Nagano-Fujii, M.3    Hidajat, R.4    Deng, L.5    Ku, Y.6    Yoon, S.7    Saito, T.8    Kawata, S.9    Hotta, H.10
  • 36
    • 0343238858 scopus 로고    scopus 로고
    • Treatment of mice with EGF and orthovanadate activates cytoplasmic and nuclear MAPK, p70S6k, and p90rsk in the liver
    • J. Ostrowski, M. Woszczynski, P. Kowalczyk, L. Trzeciak, E. Hennig, and K. Bomsztyk Treatment of mice with EGF and orthovanadate activates cytoplasmic and nuclear MAPK, p70S6k, and p90rsk in the liver J. Hepatol. 32 2000 965 974
    • (2000) J. Hepatol. , vol.32 , pp. 965-974
    • Ostrowski, J.1    Woszczynski, M.2    Kowalczyk, P.3    Trzeciak, L.4    Hennig, E.5    Bomsztyk, K.6
  • 37
    • 0037102190 scopus 로고    scopus 로고
    • MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition
    • J. Pinkas, and P. Leder MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition Cancer Res. 62 2002 4781 4790
    • (2002) Cancer Res. , vol.62 , pp. 4781-4790
    • Pinkas, J.1    Leder, P.2
  • 38
    • 0029063640 scopus 로고
    • Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells
    • D. Sakamuro, T. Furukawa, and T. Takegami Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells J. Virol. 69 1995 3893 3896
    • (1995) J. Virol. , vol.69 , pp. 3893-3896
    • Sakamuro, D.1    Furukawa, T.2    Takegami, T.3
  • 39
    • 0028832632 scopus 로고
    • The NS2 protein of hepatitis C virus is a transmembrane polypeptide
    • E. Santolini, L. Pacini, C. Fipaldini, G. Migliaccio, and N. Monica The NS2 protein of hepatitis C virus is a transmembrane polypeptide J. Virol. 69 1995 7461 7471
    • (1995) J. Virol. , vol.69 , pp. 7461-7471
    • Santolini, E.1    Pacini, L.2    Fipaldini, C.3    Migliaccio, G.4    Monica, N.5
  • 40
    • 0037593310 scopus 로고    scopus 로고
    • The proteins of the Hepatitis C virus: Their features and interactions with intracellular protein phosphorylation
    • J. Schulze zur Wiesch, H. Schmitz, E. Borowski, and P. Borowski The proteins of the Hepatitis C virus: their features and interactions with intracellular protein phosphorylation Arch. Virol. 148 2003 1247 1267
    • (2003) Arch. Virol. , vol.148 , pp. 1247-1267
    • Schulze Zur Wiesch, J.1    Schmitz, H.2    Borowski, E.3    Borowski, P.4
  • 42
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • E. Shaulian, and M. Karin AP-1 in cell proliferation and survival Oncogene 20 2001 2390 2400
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 43
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • E. Shaulian, and M. Karin AP-1 as a regulator of cell life and death Nat. Cell Biol. 5 2002 E131 E136
    • (2002) Nat. Cell Biol. , vol.5
    • Shaulian, E.1    Karin, M.2
  • 44
    • 1042279133 scopus 로고    scopus 로고
    • HCV core, NS3, NS5A and NS5B proteins modulate cell proliferation independently from p53 expression in hepatocarcinoma cell lines
    • S. Siavoshian, J.D. Abraham, M.P. Kieny, and C. Schuster HCV core, NS3, NS5A and NS5B proteins modulate cell proliferation independently from p53 expression in hepatocarcinoma cell lines Arch. Virol. 149 2004 323 336
    • (2004) Arch. Virol. , vol.149 , pp. 323-336
    • Siavoshian, S.1    Abraham, J.D.2    Kieny, M.P.3    Schuster, C.4
  • 45
    • 0027199917 scopus 로고
    • Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
    • J.A. Suzich, J.K. Tamura, F. Palmer-Hill, P. Warrener, A. Grakoui, C.M. Rice, S.M. Feinstone, and M.S. Collett Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes J. Virol. 67 1993 6152 61528
    • (1993) J. Virol. , vol.67 , pp. 6152-61528
    • Suzich, J.A.1    Tamura, J.K.2    Palmer-Hill, F.3    Warrener, P.4    Grakoui, A.5    Rice, C.M.6    Feinstone, S.M.7    Collett, M.S.8
  • 47
    • 0033729507 scopus 로고    scopus 로고
    • Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation
    • Y. Takihara, Y. Matsuda, and J. Hara Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation Carcinogenesis 21 2000 2073 2077
    • (2000) Carcinogenesis , vol.21 , pp. 2073-2077
    • Takihara, Y.1    Matsuda, Y.2    Hara, J.3
  • 48
  • 50
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
    • H. van Dam, D. Wilhelm, I. Herr, A. Steffen, P. Herrlich, and P. Angel ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents EMBO J. 14 1995 1798 1811
    • (1995) EMBO J. , vol.14 , pp. 1798-1811
    • Van Dam, H.1    Wilhelm, D.2    Herr, I.3    Steffen, A.4    Herrlich, P.5    Angel, P.6
  • 51
    • 0001929518 scopus 로고    scopus 로고
    • Effect of HCV infection on expression of several cancer-associated gene products in HCC
    • J.M. Yang, R.Q. Wang, B.G. Bu, Z.C. Zhou, D.C. Fang, and Y.H. Luo Effect of HCV infection on expression of several cancer-associated gene products in HCC World J. Gastroenterol. 5 1999 25 27
    • (1999) World J. Gastroenterol. , vol.5 , pp. 25-27
    • Yang, J.M.1    Wang, R.Q.2    Bu, B.G.3    Zhou, Z.C.4    Fang, D.C.5    Luo, Y.H.6
  • 52
    • 0013254477 scopus 로고    scopus 로고
    • Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes
    • S.H. Yang, C.G. Lee, C.W. Lee, E.J. Choi, S.K. Yoon, K.S. Ahn, and Y.C. Sung Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes Mol. Cell 13 2002 452 462
    • (2002) Mol. Cell , vol.13 , pp. 452-462
    • Yang, S.H.1    Lee, C.G.2    Lee, C.W.3    Choi, E.J.4    Yoon, S.K.5    Ahn, K.S.6    Sung, Y.C.7
  • 54
    • 0034680011 scopus 로고    scopus 로고
    • High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model
    • V. Zoumpourlis, P. Papassava, S. Linardopoulos, D. Gillespie, A. Balmain, and A. Pintzas High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model Oncogene 19 2000 4011 4021
    • (2000) Oncogene , vol.19 , pp. 4011-4021
    • Zoumpourlis, V.1    Papassava, P.2    Linardopoulos, S.3    Gillespie, D.4    Balmain, A.5    Pintzas, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.