Tau pathology: A marker of neurodegenerative disorders

Current Opinion in Neurology

Volumn 13, Issue 4, 2000, Pages 371-376

  Delacourte, A ^a   Buee, L ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN;

ALZHEIMER DISEASE; CHROMOSOME 17; DEGENERATIVE DISEASE; DEMENTIA; GENE MUTATION; HUMAN; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PARKINSONISM; PROGRESSIVE SUPRANUCLEAR PALSY; REVIEW;

ALZHEIMER DISEASE; BIOLOGICAL MARKERS; BRAIN; HUMANS; NEURODEGENERATIVE DISEASES; POLYMORPHISM, GENETIC; TAU PROTEINS;

EID: 0033851020     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-200008000-00002     Document Type: Review

References (69)

1. Non-Alzheimer degenerative dementias
2. Filamentous nerve cell inclusions in neurodegenerative diseases: Tauopathies and alpha-synucleinopathies
3. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
4. Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease
5. Progressive supranuclear palsy with dementia: Cortical pathology
6. Cortical load of PHF-tau in Alzheimer's disease is correlated to cholinergic dysfunction
7. Neuropathology of Alzheimer's disease: What is new since A. Alzheimer?
8. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease
9. A stop-codon mutation in the BRI gene associated with familial British dementia
10. Cytoskeletal pathology in familial cerebralamyloid angiopathy (British type) with non-neuritic amyloid plaque formation
11. The progression of the lesions in Alzheimer disease: Insights from a prospective clinicopathological study
12. Tangles and plaques in nondemented aging and 'preclinical' Alzheimer's disease
13. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial
14. Cognitive decline in individuals with high blood pressure: Alongitudinal study in the elderly. EVA Study Group. Epidemiology of Vascular Aging
15. Overlap between pathology of Alzheimer disease and vascular dementia
16. Sensitivity, specificity, and stability of CSF-tau in AD in a community-based patient sample
17. Tau gene mutation in familial progressive subcortical gliosis
18. Phenotypic variation in hereditary frontotemporal dementia with tau mutations
19. Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau
20. The neuropathology of a chromosome 17-linked autosomal dominant parkinsonism and dementia ('pallido-ponto-nigral degeneration')
21. A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration
22. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
23. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy
24. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
25. Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements
26. Hereditary frontotemporal dementia is linked to chromosome 17q21 -q22: A genetic and clinicopathological study of three Dutch families
27. Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism
28. A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)
29. From genotype to phenotype: A clinical pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP-17) caused by the P301L tau mutation
30. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau
31. FTDP-17: An early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation
32. Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: Expansion of the disease phenotype caused by tau gene mutations
33. 5' Splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10
34. FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10
35. A distinct familial presenile dementia with a novel missense mutation in the tau gene
36. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
37. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto)
38. Association of missense and 5'-splicesite mutations in tau with the inherited dementia FTDP-17
39. Clinical characteristics of a family with chromosome 17-linked disinhibition-dementia-parkinsonism-amyotrophy complex
40. Familial progressive subcortical gliosis: Presence of prions and linkage to chromosome 17
41. Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22
42. Missense tau mutations identified in FTDP-17 have a small effect on tau-microtubule interactions
43. Tau is a candidate gene for chromosome 17 frontotemporal dementia
44. Familial presenile dementia with psychosis associated with cortical neurofibrillary tangles and degeneration of the amygdala
45. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits
46. The tau gene in progressive supranuclear palsy: Exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases
47. A lack of the R406W tau mutation in progressive supranuclear palsy and corticobasal degeneration
48. Neurodegenerative diseases of Guam: Analysis of TAU
49. Mutation screening of the tau gene in patients with early-onset Alzheimer's disease
50. Genetic evidence for the involvement of tau in progressive supranuclear palsy
51. Direct genetic evidence for involvement of tau in progressive supranuclear palsy. European Study Group on Atypical Parkinsonism Consortium
52. Significant changes in the tau A0 and A3 alleles in progressive supranuclear palsy and improved genotyping by silver detection
53. Association of an extended haplotype in the tau gene with progressive supranuclear palsy
54. Identification of a novel polymorphism in the promoter region of the tau gene highly associated to progressive supranuclear palsy in humans
55. Mutational analysis of the tau gene in progressive supranuclear palsy
56. The tau gene A0 allele and progressive supranuclear palsy
57. The tau gene A0 polymorphism in progressive supranuclear palsy and related neurodegenerative diseases
58. Neurofibrillary tangle parkinsonian disorders-tau pathology and tau genetics
59. Molecular genetics of chromosome 17 tauopathies
60. Corticobasal degeneration shares a common genetic background with progressive supranuclear palsy
61. Significant association between the tau gene A0/A0 genotype and Parkinson's disease
62. A polymorphism in the tau gene associated with risk for Alzheimer's disease
63. Tau gene polymorphisms and apolipoprotein E epsilon4 may interact to increase risk for Alzheimer's disease
64. No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples
65. Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
66. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease
67. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease
68. Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration
69. Complex regulation of tau exon 10, whose missplicing causes frontotemporal dementia