Orally active amino functionalized antimalarial 1,2,4-trioxanes

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 2, 2004, Pages 459-462

  Singh, Chandan ^a   Malik, Heetika ^a   Puri, Sunil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ANTIMALARIAL AGENT; ARTEETHER; CHLOROQUINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; MOUSE; NONHUMAN; PLASMODIUM YOELII; PROTOZOAL INFECTION;

PLASMODIUM YOELII;

EID: 0347990510     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.10.051     Document Type: Article

References (11)

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8. 2O 80:20, Flow rate 0.8 mL/min) is around 60:40.
9. ++1). Anal. calculated: C 74.44%, H 6.66%, N 5.78%; found C 74.57%, H 6.67%, N 5.38%.
10. 11 Mice treated with arteether and chloroquine served as positive controls.
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