Chloroquine-resistant isolates of Plasmodium falciparum with alternative CG2 ω repeat length polymorphisms

American Journal of Tropical Medicine and Hygiene

Volumn 62, Issue 2, 2000, Pages 190-192

  McCutcheon, Keir R G ^a   Freese, Janet A ^b   Frean, John A ^a   Veale, Robin B ^a   Sharp, Brian L ^b   Markus, Miles B ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; REPETITIVE DNA;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; DNA POLYMORPHISM; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0034102457     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2000.62.190     Document Type: Article

References (5)

1. Wernsdorfer WH, Payne D, 1988. Drug sensitivity tests in malaria parasites. Wernsdorfer, WH, McGregor I, eds. Malaria: Principles and Practice of Malariology. Volume 2. Edinburgh: Churchill Livingstone, 1765-1794.
2. Deacon HE, Freese JA, Sharp BL, 1994. Drug-resistant Plasmodium falciparum malaria in the eastern Transvaal. S Afr Med J 84: 394-395.
3. van Nierop WH, Frean JA, Markus MB, 1996. In vitro susceptibilities of field isolates of Plasmodium falciparum to chloroquine in Mpumalanga. S Afr Med J 86: 984-985.
4. McCutcheon KRG, Veale RB, Frean JA, Markus MB, 1999. Rapid detection of cg2 polymorphisms in chloroquine-resistant and -sensitive isolates of Plasmodium falciparum. Trans R Soc Trop Med Hyg 93: 326-328.
5. Su, X-Z, Kirkman LA, Hisashi F, Wellems TE, 1997. Complex polymorphisms in an ∼330 kDa protein are linked to chloroquine-resistant P. falciparum in southeast Asia and Africa. Cell 91: 593-603.