Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action

Biochemistry

Volumn 36, Issue 6, 1997, Pages 1199-1211

  Lin, Jian ^a   Abeygunawardana, Chitrananda ^a   Frick, David N ^b,c   Bessman, Maurice J ^b   Mildvan, Albert S ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INORGANIC PYROPHOSPHATASE; NUCLEOSIDE TRIPHOSPHATE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; ESCHERICHIA COLI PROTEINS; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN CONFORMATION; PYROPHOSPHATASES; SOLUTIONS;

EID: 0031027111     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962619c     Document Type: Article

References (54)

1. Abeygunawardana, C., Weber, D. J., Frick, D. N., Bessman, M. J., & Mildvan, A. S. (1993) Biochemistry 32, 13071-13080.
2. Abeygunawardana, C., Weber, D. J., Gittis, A. G., Frick, D. N., Miller, A.-F., Bessman, M. J., Lin, J., & Mildvan, A. S. (1995) Biochemistry 34, 14997-15005.
3. Abeygunawardana, C., Mori, S., Van Zihl, P. C. M., & Mildvan, A. S. (1996) 34th Experimental NMR Conference, Pacific Grove, CA, abstract WP4, p 224, ENC Publications, Santa Fe, NM.
4. Bax, A., Clore, G. M., & Gronenborn, A. M. (1990) J. Magn. Reson. 88, 425-431.
5. Bessman, M. J., Frick, D. N., & O'Handley, S. F. (1996) J. Biol. Chem. 271, 25059-25066.
6. Bhatnagar, S. K., Bullions, L. C., & Bessman, M. J. (1991) J. Biol. Chem. 266, 9050-9054.
7. Bodenhausen, G., & Ruben, D. J. (1980) Chem. Phys. Lett. 69, 185-188.
8. Brooks, R. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S., & Karplus, M. J. (1983) J. Comput. Chem. 4, 187-217.
9. Brünger, A. T. (1992) X-PLOR Version 3.1. A system for X-ray crystallography and NMR, Yale University Press, New Haven, CT.
10. Cheng, K. C., Cahill, D. S., Kasai, H., Nishimura, S., & Loeb, L. A. (1991) J. Biol. Chem. 267, 166-172.
11. Cleland, W. W., & Mildvan, A. S. (1979) in Advances in Inorganic Biochemistry (Eichorn, G. L., & Marzilli, L.,Eds.) Vol. 1, pp 163-191, Elsevier, New York.
12. Clore, G. M., Nilges, M., Sukumaran, D. K., Brünger, A. T., Karplus, M., & Gronenborn, A. M. (1986) EMBO 5, 2729-2735.
13. Clore, G. M., Gronenborn, A. M., Nilges, M., & Ryan, C. A. (1987) Biochemistry 26, 8012-8013.
14. Cornelius, R. D., Hart, P. A., & Cleland, W. W. (1977) Inorg. Chem. 16, 2799-2805.
15. Frick, D. N., Weber, D. J., Gillespie, J. R., Bessman, M. J., & Mildvan, A. S. (1994) J. Biol. Chem. 269, 1794-1803.
16. Frick, D. N., Weber, D. J., Abeygunawardana, C., Gittis, A. G., Bessman, M. J., & Mildvan, A. S. (1995) Biochemistry 34, 5577-5586.
17. Granot, J., Gibson, K. J., Switzer, R. L., & Mildvan, A. S. (1980a) J. Biol. Chem. 255, 10931-10937.
18. Granot, J., Mildvan, A. S., Bramson, H. N., & Kaiser, E. T. (1980b) Biochemistry 19, 3537-3543.
19. Kakuma, T., Nishida, J., Tsuzuki, T., & Sekiguchi, M. (1995) J. Biol. Chem. 270, 25942-25948.
20. Kay, L. E. (1993) J. Am. Chem. Soc. 115, 2055-2057.
21. Kay, L. E., & Bax, A. (1990) J. Magn. Reson. 86, 110-126.
22. Kay, L. E., Xu, G.-Y., Singer, A. U., Muhandiram, D. R., & Forman-Kay, J. D. (1993) J. Magn. Reson. 101B, 333-337.
23. Kaziro, Y. (1956) J. Biochem. (Tokyo) 46, 1523-1539.
24. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
25. Lee, W., Revington, M. J., Arrowsmith, C. & Kay, L. E. (1994) FEBS Lett. 350, 87-90.
26. Lee, W., Revington, M., Farrow, N. A., Nakamura, A., Utsunomiya-Tate, N., Miyake, Y., Kainosho, M., & Arrowsmith, C. H. (1995) J. Biomol. NMR 5, 367-375.
27. Levy, G. C., & Lichter, R. L. (1979) Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy, John Wiley & Sons, New York.
28. Lin, J., Abeygunawardana, C., Frick, D. N., Bessman, M. J., & Mildvan, A. S. (1996) Biochemistry 35, 6715-6726.
29. Maki, H., & Sekiguchi, M. (1992) Nature 355, 273-275.
30. Marion, D., & Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 967-974.
31. Marion, D., Ikura, M., Tschudin, R., & Bax, A. (1989) J. Magn. Reson. 85, 393-399.
32. Mehdi, S., & Gerlt, J. A. (1982) J. Am. Chem. Soc. 104, 3223-3225.
33. Mildvan, A. S. (1981) Philos. Trans. R. Soc. London Ser. B 293, 65-74.
34. Mildvan, A. S., & Gupta, R. K. (1978) Methods Enzymol. 49G, 322-359.
35. Mildvan, A. S., & Fry, D. C. (1987) Adv. Enzymol. 59, 241-313.
36. Mildvan, A. S., Weber, D. J., & Kuliopulos, A. (1992) Arch. Biochem. Biophys. 294, 327-340.
37. Mo, J. Y., Maki, H., & Sekiguchi, M. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 11021-11025.
38. Mori, S., Abeygunawardana, C., Johnson, M. O., & van Zijl, P. C. M. (1995) J. Magn. Reson. 108B, 94-98.
39. Muhandiram, D. R., Farrow, N. A., Xu, G.-Y., Smallcombe, S. H., & Kay, L. E. (1993) J. Magn. Reson. 102B, 317-321.
40. Nilges, M., Clore, G. M., & Gronenborn, A. M. (1988) FEBS Lett. 229, 317-324.
41. O'Handley, S. F., Frick, D. N., Bullions, L. C. Mildvan, A. S., & Bessman, M. J. (1996) J. Biol. Chem. 271, 24649-24654.
42. Sakumi, K., Furuichi, M., Tsuzuki, T., Kakuma, T., Kawabata, S., Maki, H., & Sekiguchi, M. (1993) J. Biol. Chem. 268, 23524-23530.
43. Serpersu, E. H., McCracken, J., Peisach, J., & Mildvan, A. S. (1988) Biochemistry 27, 8034-8044.
44. Talarico, T. L., Ray, P. H., Dev, I. K., Merrill, B. M., & Dallas, W. S. (1992) J. Bacteriol. 174, 5971-5977.
45. Van Wazer, J. R., Griffith, E. J., & McCullough, J. F. (1955) J. Am. Chem. Soc. 77, 287-291.
46. Villafranca, J. J., & Mildvan, A. S. (1972) J. Biol. Chem. 247, 3454-3463.
47. Vuister, G. W., & Bax, A. (1992) J. Magn. Reson. 98, 428-435.
48. Weber, D. J., Mullen, G. P., & Mildvan, A. S. (1991) Biochemistry 30, 7425-7437.
49. Weber, D. J., Bhatnagar, S. K., Bullions, L. C., Bessman, M. J., & Mildvan, A. S. (1992a) J. Biol. Chem. 267, 16939-16942.
50. Weber, D. J., Gittis, A. G., Mullen, G. P., Abeygunawardana, C., Lattman, E. E., & Mildvan, A. S. (1992b) Proteins: Struct., Funct., Genet. 13, 275-287.
51. Weber, D. J., Abeygunawardana, C., Bessman, M. J., & Mildvan, A. S. (1993) Biochemistry 32, 13081-13088.
52. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, pp 166-168, John Wiley & Sons, New York.
53. Wüthrich, K., Billetter, M., & Braun, W. (1983) J. Mol. Biol. 169, 949-961.
54. Yanofsky, C., Cox, E. C., & Horn, V. (1966) Proc. Natl. Acad. Sci. U.S.A. 55, 274-281.