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Volumn 9, Issue 2, 2004, Pages 160-172

In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication

Author keywords

Gene therapy; HIV; Lentivirus; MGMT; Selection; Stem cell; T lymphocyte

Indexed keywords

6 O BENZYLGUANINE; CARMUSTINE; CD4 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; LENTIVIRUS VECTOR; LEUKOSIALIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

EID: 1342290228     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.11.003     Document Type: Article
Times cited : (42)

References (36)
  • 1
    • 0003547733 scopus 로고    scopus 로고
    • Joint United Nations Programme on HIV/AIDS
    • WHO/UNAIDS, Geneva
    • Joint United Nations Programme on HIV/AIDS (2003). AIDS Epidemic Updates. WHO/UNAIDS, Geneva.
    • (2003) AIDS Epidemic Updates
  • 2
    • 84942477924 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention
    • CDC, Atlanta
    • Centers for Disease Control and Prevention (2001). HIV/AIDS Surveillance Report, Vol. 13. CDC, Atlanta.
    • (2001) HIV/AIDS Surveillance Report , vol.13
  • 3
    • 85030881160 scopus 로고    scopus 로고
    • 11th International Workshop on HIV Drug Resistance. Rapid Report. Seville, July 2-5, 2002
    • th International Workshop on HIV Drug Resistance (2002). Rapid Report. Seville, July 2-5, 2002.
    • (2002)
  • 4
    • 0037043652 scopus 로고    scopus 로고
    • Antiretroviral-drug resistance among patients recently infected with HIV
    • Little, S. J., et al. (2002). Antiretroviral-drug resistance among patients recently infected with HIV. N. Engl. J. Med. 347: 385-394.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 385-394
    • Little, S.J.1
  • 5
    • 0032707973 scopus 로고    scopus 로고
    • Adverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV disease
    • Vigouroux, C., et al. (1999). Adverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV disease. Diabetes Metab. 25: 383-392.
    • (1999) Diabetes Metab. , vol.25 , pp. 383-392
    • Vigouroux, C.1
  • 6
    • 0033933880 scopus 로고    scopus 로고
    • Lipodystrophy syndrome in HIV infection
    • Behrens, G. M., Stoll, M., and Schmidt, R. E. (2000). Lipodystrophy syndrome in HIV infection. Drug Saf. 23: 57-76.
    • (2000) Drug Saf. , vol.23 , pp. 57-76
    • Behrens, G.M.1    Stoll, M.2    Schmidt, R.E.3
  • 8
    • 0035513970 scopus 로고    scopus 로고
    • Clinical protocol: A phase I open-label clinical trial of the safety and tolerability of single escalating doses of autologous CD4 T cells transduced with VRX496 in HIV-positive subjects
    • MacGregor, R. R. (2001). Clinical protocol: a phase I open-label clinical trial of the safety and tolerability of single escalating doses of autologous CD4 T cells transduced with VRX496 in HIV-positive subjects. Hum. Gene Ther. 12: 2028-2029.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 2028-2029
    • MacGregor, R.R.1
  • 9
    • 0029764099 scopus 로고    scopus 로고
    • A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread
    • Dropulic, B., Hernankova, M., and Pitha, P. M. (1996). A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread. Proc. Natl. Acad. Sci. USA 93: 11103-11108.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11103-11108
    • Dropulic, B.1    Hernankova, M.2    Pitha, P.M.3
  • 10
    • 1342305771 scopus 로고    scopus 로고
    • Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection
    • Walker, R. E., et al. (1998). Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection. Blood 92: 1131-1141.
    • (1998) Blood , vol.92 , pp. 1131-1141
    • Walker, R.E.1
  • 11
    • 0036157376 scopus 로고    scopus 로고
    • + T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection
    • + T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection. Nat. Med. 8: 47-53.
    • (2002) Nat. Med. , vol.8 , pp. 47-53
    • Levine, B.L.1
  • 12
    • 0038446699 scopus 로고    scopus 로고
    • Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: Long-term results of the first clinical gene therapy trial
    • Muul, L. M., et al. (2003). Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial. Blood 101: 2563-2569.
    • (2003) Blood , vol.101 , pp. 2563-2569
    • Muul, L.M.1
  • 13
    • 18444376150 scopus 로고    scopus 로고
    • Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement
    • Aiuti, A., et al. (2002). Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement. Nat. Med. 8: 423-425.
    • (2002) Nat. Med. , vol.8 , pp. 423-425
    • Aiuti, A.1
  • 14
    • 12644293807 scopus 로고    scopus 로고
    • Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease
    • Malech, H. L., et al. (1997). Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. Proc. Natl. Acad. Sci. USA 94: 12133-12138.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12133-12138
    • Malech, H.L.1
  • 15
    • 0032553681 scopus 로고    scopus 로고
    • + cells from patients with Gaucher disease: In vivo detection of transduced cells without myeloablation
    • + cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation. Hum. Gene Ther. 9: 2629-2640.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2629-2640
    • Dunbar, C.E.1
  • 16
    • 0033168686 scopus 로고    scopus 로고
    • A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children
    • Kohn, D. B., et al. (1999). A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children. Blood 94: 368-371.
    • (1999) Blood , vol.94 , pp. 368-371
    • Kohn, D.B.1
  • 17
    • 0032809319 scopus 로고    scopus 로고
    • Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients
    • Cowan, K. H., et al. (1999). Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. Clin. Cancer Res. 5: 1619-1628.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1619-1628
    • Cowan, K.H.1
  • 18
    • 0031972859 scopus 로고    scopus 로고
    • Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation
    • Hesdorffer, C., et al. (1998). Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation. J. Clin. Oncol. 16: 165-172.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 165-172
    • Hesdorffer, C.1
  • 19
    • 0034724857 scopus 로고    scopus 로고
    • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
    • Cavazzana-Calvo, M., et al. (2000). Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288: 669-672.
    • (2000) Science , vol.288 , pp. 669-672
    • Cavazzana-Calvo, M.1
  • 20
    • 0034131481 scopus 로고    scopus 로고
    • Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
    • Abonour, R., et al. (2000). Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat. Med. 6: 652-658.
    • (2000) Nat. Med. , vol.6 , pp. 652-658
    • Abonour, R.1
  • 21
    • 0026637623 scopus 로고
    • Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human
    • Sorrentino, B.P., et al. (1992). Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. 257: 99-103.
    • (1992) MDR1 , vol.257 , pp. 99-103
    • Sorrentino, B.P.1
  • 22
    • 0026705269 scopus 로고
    • Transfer and expression of the human multiple drug resistance gene into live mice
    • Podda, S., et al. (1992). Transfer and expression of the human multiple drug resistance gene into live mice. Proc. Natl. Acad. Sci. USA 89: 9676-9680.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9676-9680
    • Podda, S.1
  • 23
    • 0025089990 scopus 로고
    • Serial transplantation of methotrexate-resistant bone marrow: Protection of murine recipients from drug toxicity by progeny of transduced stem cells
    • Corey, C. A., DeSilva, A. D., Holland, C. A., and Williams, D. A. (1990). Serial transplantation of methotrexate-resistant bone marrow: protection of murine recipients from drug toxicity by progeny of transduced stem cells. Blood 75: 337-343.
    • (1990) Blood , vol.75 , pp. 337-343
    • Corey, C.A.1    DeSilva, A.D.2    Holland, C.A.3    Williams, D.A.4
  • 24
    • 0031721636 scopus 로고    scopus 로고
    • In vivo selection of retrovirally transduced hematopoietic stem cells
    • Allay, J. A., et al. (1998). In vivo selection of retrovirally transduced hematopoietic stem cells. Nat. Med. 4: 1136-1143.
    • (1998) Nat. Med. , vol.4 , pp. 1136-1143
    • Allay, J.A.1
  • 26
    • 0034657950 scopus 로고    scopus 로고
    • Limiting numbers of G156A O(6)-methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection
    • Davis, B. M., Koc, O. N., and Gerson, S. L. (2000). Limiting numbers of G156A O(6)-methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection. Blood 95: 3078-3084.
    • (2000) Blood , vol.95 , pp. 3078-3084
    • Davis, B.M.1    Koc, O.N.2    Gerson, S.L.3
  • 27
    • 0034665336 scopus 로고    scopus 로고
    • Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells
    • Ragg, S., et al. (2000). Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells. Cancer Res. 60: 5187-5195.
    • (2000) Cancer Res. , vol.60 , pp. 5187-5195
    • Ragg, S.1
  • 30
    • 0034255163 scopus 로고    scopus 로고
    • High dose therapy and autologous stem cell transplantation for human immunodeficiency virus-associated non-Hodgkin lymphoma in the era of highly active antiretroviral therapy
    • Molina, A., et al. (2000). High dose therapy and autologous stem cell transplantation for human immunodeficiency virus-associated non-Hodgkin lymphoma in the era of highly active antiretroviral therapy. Cancer 89: 680-689.
    • (2000) Cancer , vol.89 , pp. 680-689
    • Molina, A.1
  • 32
    • 0036226607 scopus 로고    scopus 로고
    • + hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro
    • + hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro. Mol. Ther. 5: 381-387.
    • (2002) Mol. Ther. , vol.5 , pp. 381-387
    • Zielske, S.P.1    Gerson, S.L.2
  • 33
    • 0037772187 scopus 로고    scopus 로고
    • Successful treatment of murine {beta}-thalassemia using in vivo selection of genetically-modified, drug-resistant hematopoietic stem cells
    • Persons, D. A., et al. (2003). Successful treatment of murine {beta}-thalassemia using in vivo selection of genetically-modified, drug-resistant hematopoietic stem cells. Blood 102: 506-513.
    • (2003) Blood , vol.102 , pp. 506-513
    • Persons, D.A.1
  • 34
    • 1342284595 scopus 로고    scopus 로고
    • Efficient in vivo selection of hematopoietic stem cells in a large animal model using MGMT and O6BG/temozolomide
    • (Abstract)
    • Neff, T., et al. (2003). Efficient in vivo selection of hematopoietic stem cells in a large animal model using MGMT and O6BG/temozolomide. ASGT (Abstract).
    • (2003) ASGT
    • Neff, T.1
  • 35
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., et al. (1986). Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59: 284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1


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