Mutated p21/WAF/CIP transgene overexpression reduces smooth muscle cell proliferation, macrophage deposition, oxidation-sensitive mechanisms, and restenosis in hypercholesterolemic apolipoprotein E knockout mice

FASEB Journal

Volumn 15, Issue 12, 2001, Pages 2162-2170

  Condorelli, Gianluigi ^a,b   Aycock, Joyce K ^a,b   Frati, Giacomo ^a,b   Napoli, Claudio ^c,d  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apo E knock out; Apoptosis; Cell cycle; Gene therapy

Indexed keywords

APOLIPOPROTEIN E; PROTEIN P21;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESTENOSIS; TRANSGENE; VASCULAR SMOOTH MUSCLE;

ADENOVIRIDAE; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ARTERIES; ARTERIOSCLEROSIS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; GENE THERAPY; GENETIC VECTORS; HYPERCHOLESTEROLEMIA; MACROPHAGES; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MUTATION; OXIDATION-REDUCTION; TRANSDUCTION, GENETIC; TRANSGENES;

ADENOVIRIDAE; ANIMALIA;

EID: 0034816303     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.01-0032com     Document Type: Article

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