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Volumn 277, Issue 3 46-3, 1999, Pages

Vascular smooth muscle cell growth arrest on blockade of thrombospondin- 1 requires p21(Cip1/WAF1)

Author keywords

Cell cycle control; Extracellular matrix; p21(Cip1 WAF1); Thrombospondin

Indexed keywords

PROTEIN P21; THROMBOSPONDIN 1;

EID: 0032888184     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.3.h1100     Document Type: Article
Times cited : (25)

References (59)
  • 1
    • 0030068744 scopus 로고    scopus 로고
    • Myogenin expression, cell cycle withdrawal and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis
    • Andrés, V., and K. Walsh. Myogenin expression, cell cycle withdrawal and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. J. Cell Biol. 132: 657-666, 1996.
    • (1996) J. Cell Biol. , vol.132 , pp. 657-666
    • Andrés, V.1    Walsh, K.2
  • 2
    • 0029806559 scopus 로고    scopus 로고
    • The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis
    • Assoian, R. K., and E. E. Marcantonio. The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis. J. Clin. Invest. 98: 2436-2439, 1996.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2436-2439
    • Assoian, R.K.1    Marcantonio, E.E.2
  • 3
    • 0029347102 scopus 로고
    • Diversity of function is inherent in matricellular proteins: An appraisal of thrombospondin 1
    • Bornstein, P. Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1. J. Cell Biol. 130: 503-506, 1995.
    • (1995) J. Cell Biol. , vol.130 , pp. 503-506
    • Bornstein, P.1
  • 5
    • 0025978352 scopus 로고
    • Control of growth and differentiation of vascular cells by extracellular matrix proteins
    • Carey, D. J. Control of growth and differentiation of vascular cells by extracellular matrix proteins. Annu. Rev. Physiol. 53: 161-177, 1991.
    • (1991) Annu. Rev. Physiol. , vol.53 , pp. 161-177
    • Carey, D.J.1
  • 6
    • 0028815552 scopus 로고
    • Adenovirus-mediated over-expression of the cyclin/ cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty
    • Chang, M. W., E. Barr, M. M. Lu, K. Barton, and J. M. Leiden. Adenovirus-mediated over-expression of the cyclin/ cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J. Clin. Invest. 96: 2260-2268, 1995.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2260-2268
    • Chang, M.W.1    Barr, E.2    Lu, M.M.3    Barton, K.4    Leiden, J.M.5
  • 8
    • 0028978183 scopus 로고
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82: 675-684, 1995.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 9
    • 0030003153 scopus 로고    scopus 로고
    • Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein
    • Dimri, G. P., M. Nakanishi, P.-Y. Desprez, J. R. Smith, and J. Campisi. Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein. Mol. Cell. Biol. 16: 2987-2997, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2987-2997
    • Dimri, G.P.1    Nakanishi, M.2    Desprez, P.-Y.3    Smith, J.R.4    Campisi, J.5
  • 10
    • 0022513618 scopus 로고
    • Characterization of a cDNA encoding the heparin and collagen binding domains of human thrombospondin
    • Dixit, V. M., S. W. Hennessy, G. A. Grant, P. Rotwein, and W. A. Frazier. Characterization of a cDNA encoding the heparin and collagen binding domains of human thrombospondin. Proc. Natl. Acad. Sci. USA 83: 5449-5453, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5449-5453
    • Dixit, V.M.1    Hennessy, S.W.2    Grant, G.A.3    Rotwein, P.4    Frazier, W.A.5
  • 11
    • 0027415654 scopus 로고
    • A serum response element and binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene
    • Framson, P., and P. Bornstein. A serum response element and binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene. J. Biol. Chem. 268: 4989-4996, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4989-4996
    • Framson, P.1    Bornstein, P.2
  • 12
    • 0030028147 scopus 로고    scopus 로고
    • Molecular therapies for vascular diseases
    • Gibbons, G. H., and V. J. Dzau. Molecular therapies for vascular diseases. Science 272: 689-693, 1996.
    • (1996) Science , vol.272 , pp. 689-693
    • Gibbons, G.H.1    Dzau, V.J.2
  • 13
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D. J., P. J. Polverini, F. Rastinejad, M. M. Le Beau, R. S. Lemons, W. A. Frazier, and N. P. Bouck. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA 87: 6624-6628, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6    Bouck, N.P.7
  • 14
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
    • Graña, X., and E. P. Reddy. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11: 211-219, 1995.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Graña, X.1    Reddy, E.P.2
  • 15
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816, 1993.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 16
    • 0030044817 scopus 로고    scopus 로고
    • Cdk inhibitors in development and cancer
    • Harper, J. W., and S. J. Elledge. Cdk inhibitors in development and cancer. Curr. Opin. Genet. Dev. 6: 56-64, 1996.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 56-64
    • Harper, J.W.1    Elledge, S.J.2
  • 17
    • 0027967944 scopus 로고
    • Rules to replicate by
    • Heichman, K. A., and J. M. Roberts. Rules to replicate by. Cell 79: 557-562, 1994.
    • (1994) Cell , vol.79 , pp. 557-562
    • Heichman, K.A.1    Roberts, J.M.2
  • 18
    • 0025853349 scopus 로고
    • Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro
    • Iruela-Arispe, M. L., P. Bornstein, and H. Sage. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc. Natl. Acad. Sci. USA 88: 5026-5030, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5026-5030
    • Iruela-Arispe, M.L.1    Bornstein, P.2    Sage, H.3
  • 19
    • 0021933434 scopus 로고
    • Monocytes and macrophages synthesize and secrete thrombospondin
    • Jaffe, E. A., J. T. Ruggiero, and D. J. Falcone. Monocytes and macrophages synthesize and secrete thrombospondin. Blood 65: 79-84, 1985.
    • (1985) Blood , vol.65 , pp. 79-84
    • Jaffe, E.A.1    Ruggiero, J.T.2    Falcone, D.J.3
  • 20
    • 0343951615 scopus 로고
    • Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix
    • Jaffe, E. A., J. T. Ruggiero, L. K. Leung, M. J. Doyle, McKeown, P. J. Longo, and D. F. Mosher. Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix. Proc. Natl. Acad. Sci. USA 80: 998-1002, 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 998-1002
    • Jaffe, E.A.1    Ruggiero, J.T.2    Leung, L.K.3    Doyle, M.J.4    McKeown5    Longo, P.J.6    Mosher, D.F.7
  • 21
    • 0027459771 scopus 로고
    • Signal transduction from the extracellular matrix
    • Juliano, R. L., and S. Haskill. Signal transduction from the extracellular matrix. J. Cell Biol. 120: 577-585, 1993.
    • (1993) J. Cell Biol. , vol.120 , pp. 577-585
    • Juliano, R.L.1    Haskill, S.2
  • 22
    • 0030582716 scopus 로고    scopus 로고
    • Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of cdk2 inhibitors
    • Koyama, H., E. W. Raines, K. E. Bornfeldt, J. M. Roberts, and R. Ross. Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of cdk2 inhibitors. Cell 87: 1069-1078, 1996.
    • (1996) Cell , vol.87 , pp. 1069-1078
    • Koyama, H.1    Raines, E.W.2    Bornfeldt, K.E.3    Roberts, J.M.4    Ross, R.5
  • 25
    • 0018253429 scopus 로고
    • Isolation and characterization of a high molecular weight glycoprotein from human blood platelets
    • Lawler, J., H. S. Slayter, and J. E. Coligan. Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. J. Biol. Chem. 253: 8609-8616, 1978.
    • (1978) J. Biol. Chem. , vol.253 , pp. 8609-8616
    • Lawler, J.1    Slayter, H.S.2    Coligan, J.E.3
  • 26
    • 0027717959 scopus 로고
    • Dietary-induced atherosclerotic lesions have increased levels of acidic FGF mRNA and altered cytoskeletal and extracellular matrix mRNA expression
    • Liau, G., J. A. Winkles, M. S. Cannon, L. Kuo, and W. M. Chilian. Dietary-induced atherosclerotic lesions have increased levels of acidic FGF mRNA and altered cytoskeletal and extracellular matrix mRNA expression. J. Vasc. Res. 30: 327-332, 1993
    • (1993) J. Vasc. Res. , vol.30 , pp. 327-332
    • Liau, G.1    Winkles, J.A.2    Cannon, M.S.3    Kuo, L.4    Chilian, W.M.5
  • 27
    • 0038866299 scopus 로고
    • Control of smooth muscle cell growth by components of the extracellular matrix: Autocrine role for thrombospondin
    • Majack, R. A., S. C. Cook, and P. Bornstein. Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. Proc. Natl. Acad. Sci. USA 83: 9050-9054, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9050-9054
    • Majack, R.A.1    Cook, S.C.2    Bornstein, P.3
  • 28
    • 0022250251 scopus 로고
    • Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells
    • Majack, R. A., S. C. Cook, and P. Bornstein. Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells. J. Cell Biol. 101: 1059-1071, 1985.
    • (1985) J. Cell Biol. , vol.101 , pp. 1059-1071
    • Majack, R.A.1    Cook, S.C.2    Bornstein, P.3
  • 29
    • 0023875603 scopus 로고
    • Cell surface thrombospondin is functionally essential for vascular smooth muscle cell proliferation
    • Majack, R. A., L. V. Goodman, and V. M. Dixit. Cell surface thrombospondin is functionally essential for vascular smooth muscle cell proliferation. J. Cell Biol. 106: 415-422, 1988.
    • (1988) J. Cell Biol. , vol.106 , pp. 415-422
    • Majack, R.A.1    Goodman, L.V.2    Dixit, V.M.3
  • 30
    • 0023664529 scopus 로고
    • Induction of thrombospondin messenger RNA levels occurs as an immediate primary response to platelet-derived growth factor
    • Majack, R. A., J. Mildbrandt, and V. M. Dixit. Induction of thrombospondin messenger RNA levels occurs as an immediate primary response to platelet-derived growth factor. J. Biol. Chem. 262: 8821-8825, 1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 8821-8825
    • Majack, R.A.1    Mildbrandt, J.2    Dixit, V.M.3
  • 31
    • 0019774169 scopus 로고
    • Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture: Apparent identity with platelet thrombospondin
    • McPherson, J., H. Sage, and P. Bornstein. Isolation and Characterization of a glycoprotein secreted by aortic endothelial cells in culture: apparent identity with platelet thrombospondin. J. Biol. Chem. 256: 11330-11336, 1981.
    • (1981) J. Biol. Chem. , vol.256 , pp. 11330-11336
    • McPherson, J.1    Sage, H.2    Bornstein, P.3
  • 32
    • 0028931265 scopus 로고
    • Principle of cdk regulation
    • Morgan, D. O. Principle of cdk regulation. Nature 374: 131-134, 1995.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 34
    • 0026499722 scopus 로고
    • COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins
    • Oldberg, A., P. Antonsson, K. Lindblom, and D. Heinegard. COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. J. Biol. Chem. 267: 22346-22350, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22346-22350
    • Oldberg, A.1    Antonsson, P.2    Lindblom, K.3    Heinegard, D.4
  • 35
    • 0029048550 scopus 로고
    • Regulation of differentiation of vascular smooth muscle cells
    • Owens, G. K. Regulation of differentiation of vascular smooth muscle cells. Physiol. Rev. 75: 487-517, 1995.
    • (1995) Physiol. Rev. , vol.75 , pp. 487-517
    • Owens, G.K.1
  • 36
    • 0032980425 scopus 로고    scopus 로고
    • Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors
    • Parry, D., D. Mahony, K. Wills, and E. Lees. Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors. Mol. Cell. Biol. 19: 1775-1783, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1775-1783
    • Parry, D.1    Mahony, D.2    Wills, K.3    Lees, E.4
  • 37
    • 0028072520 scopus 로고
    • Joining the complex: Cyclin-dependent kinase inhibitory proteins and the cell cycle
    • Peter, M., and I. Herskowitz. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 79: 181-184, 1994.
    • (1994) Cell , vol.79 , pp. 181-184
    • Peter, M.1    Herskowitz, I.2
  • 39
    • 0026466922 scopus 로고
    • Smooth muscle cell outgrowth from human atherosclerotic plaque: Implications for the assessment of lesion biology
    • Pickering, J. G., L. Weir, K. Rosenfield, J. Stetz, J. Jekanowski, and J. M. Isner. Smooth muscle cell outgrowth from human atherosclerotic plaque: implications for the assessment of lesion biology. J. Am. Coll. Cardiol. 20: 1430-1439, 1992.
    • (1992) J. Am. Coll. Cardiol. , vol.20 , pp. 1430-1439
    • Pickering, J.G.1    Weir, L.2    Rosenfield, K.3    Stetz, J.4    Jekanowski, J.5    Isner, J.M.6
  • 40
    • 0025977372 scopus 로고
    • The properdin-like type I repeats of human thrombospondin contain a cell attachment site
    • Prater, C. A., J. Plotkin, D. Jaye, and W. A. Frazier. The properdin-like type I repeats of human thrombospondin contain a cell attachment site. J. Cell Biol. 112: 1031-1040, 1991.
    • (1991) J. Cell Biol. , vol.112 , pp. 1031-1040
    • Prater, C.A.1    Plotkin, J.2    Jaye, D.3    Frazier, W.A.4
  • 41
    • 0028107296 scopus 로고
    • Thrombospondin 3 is a developmentally regulated heparin binding protein
    • Qabar, A. N., Z. Lin, F. W. Wolf, K. S. O'Shea, J. Lawler, and V. M. Dixit. Thrombospondin 3 is a developmentally regulated heparin binding protein. J. Biol. Chem. 269: 1262-1269, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1262-1269
    • Qabar, A.N.1    Lin, Z.2    Wolf, F.W.3    O'Shea, K.S.4    Lawler, J.5    Dixit, V.M.6
  • 45
    • 0026080765 scopus 로고
    • Proteoglycans as modulators of growth factor activities
    • Ruoslathi, E., and Y. Yamaguchi. Proteoglycans as modulators of growth factor activities. Cell 64: 867-869, 1991.
    • (1991) Cell , vol.64 , pp. 867-869
    • Ruoslathi, E.1    Yamaguchi, Y.2
  • 49
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr, C. J. G1 phase progression: cycling on cue. Cell 79: 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 50
    • 0000813866 scopus 로고    scopus 로고
    • Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
    • Spyridopoulos, I., and V. Andrés. Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease. Front. Biosc. 3: 269-287, 1998.
    • (1998) Front. Biosc. , vol.3 , pp. 269-287
    • Spyridopoulos, I.1    Andrés, V.2
  • 51
    • 0032502061 scopus 로고    scopus 로고
    • β3 integrins are upregulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells
    • Stouffer, G. A., Z. Hu, M. Sajid, H. Li, G. Jin, M. T. Nakada, S. R. Hanson, and M. S. Runge. β3 integrins are upregulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells. Circulation 97: 907-915, 1998.
    • (1998) Circulation , vol.97 , pp. 907-915
    • Stouffer, G.A.1    Hu, Z.2    Sajid, M.3    Li, H.4    Jin, G.5    Nakada, M.T.6    Hanson, S.R.7    Runge, M.S.8
  • 52
    • 0032031659 scopus 로고    scopus 로고
    • Role of c-fos and E2F in the induction of cyclin a transcription and vascular smooth muscle cell proliferation
    • Sylvester, A. M., D. Chen, K. Krasinski, and V. Andrés. Role of c-fos and E2F in the induction of cyclin A transcription and vascular smooth muscle cell proliferation. J. Clin. Invest. 101: 940-948, 1998.
    • (1998) J. Clin. Invest. , vol.101 , pp. 940-948
    • Sylvester, A.M.1    Chen, D.2    Krasinski, K.3    Andrés, V.4
  • 54
    • 0025370524 scopus 로고
    • Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor
    • Taraboletti, G., D. Roberts, L. A. Liotta, and R. Giavazzi. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor. J. Cell Biol. 111: 765-772, 1990.
    • (1990) J. Cell Biol. , vol.111 , pp. 765-772
    • Taraboletti, G.1    Roberts, D.2    Liotta, L.A.3    Giavazzi, R.4
  • 55
    • 0030750148 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of cyclin-dependent kinase inhibitor-p21 suppresses neointimal formation in the balloon-injured rat carotid arteries in vivo
    • Ueno, H., S. Masuda, S. Nishio, J. J. Li, H. Yamamoto, and A. Takeshita. Adenovirus-mediated transfer of cyclin-dependent kinase inhibitor-p21 suppresses neointimal formation in the balloon-injured rat carotid arteries in vivo. Ann. NY Acad. Sci. 811: 401-411, 1997.
    • (1997) Ann. NY Acad. Sci. , vol.811 , pp. 401-411
    • Ueno, H.1    Masuda, S.2    Nishio, S.3    Li, J.J.4    Yamamoto, H.5    Takeshita, A.6
  • 57
    • 0031947966 scopus 로고    scopus 로고
    • The thrombospondin receptor CD47 (IAP) modulates and associates with α2β1 integrin in vascular smoth muscle cells
    • Wang, X.-Q., and W. A. Frazier. The thrombospondin receptor CD47 (IAP) modulates and associates with α2β1 integrin in vascular smoth muscle cells. Mol. Biol. Cell 9: 865-874, 1998.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 865-874
    • Wang, X.-Q.1    Frazier, W.A.2
  • 58
    • 0029794891 scopus 로고    scopus 로고
    • Role of p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury
    • Yang, Z.-Y., R. D. Simari, N. D. Perkins, H. San, D. Gordon, G. J. Nabel, and E. G. Nabel. Role of p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury. Proc. Natl. Acad. Sci. USA 93: 7905-7910, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7905-7910
    • Yang, Z.-Y.1    Simari, R.D.2    Perkins, N.D.3    San, H.4    Gordon, D.5    Nabel, G.J.6    Nabel, E.G.7


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