High-throughput detection of multiple genetic polymorphisms influencing drug metabolism with mismatch primers in allele-specific polymerase chain reaction

Analytical Biochemistry

Volumn 337, Issue 2, 2005, Pages 256-261

  Ishiguro, Akihiro ^a   Kubota, Takahiro ^a   Soya, Yoshihiro ^b   Sasaki, Hiroshi ^c   Yagyu, Osamu ^d   Takarada, Yutaka ^b   Iga, Tatsuji ^a  

^a UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^b TOYOBO CO LTD   (Japan)

^c SRL INC   (Japan)

^d Corona Electric Company Ltd ^*  (Japan)

Author keywords

Allele specific PCR; Drug metabolizing enzyme; Genetic polymorphism; Genotyping; Stepdown PCR

Indexed keywords

ENZYMES; GENES; METABOLISM; POLYMORPHISM;

ALLELE-SPECIFIC PCR; DRUG-METABOLIZING ENZYMES; GENETIC POLYMORPHISMS; GENOTYPING; STEPDOWN PCR;

POLYMERASE CHAIN REACTION;

DRUG METABOLIZING ENZYME; GENOMIC DNA;

ALLELE; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; DRUG METABOLISM; GENE STRUCTURE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HIGH THROUGHPUT SCREENING; HUMAN; MUTATION; NORMAL HUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

EID: 13244283273     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.11.038     Document Type: Article

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