Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 8, 2000, Pages 3878-3883

  Karlstrom, Amelie ^a   Zhong, Guofu ^a   Rader, Christoph ^a   Larsen, Nicholas A ^a   Heine, Andreas ^a   Fuller, Roberta ^a   List, Benjamin ^a   Tanaka, Fujie ^a   Wilson, Ian A ^a   Barbas III, Carlos F ^a   Lerner, Richard A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOLASE ANTIBODY; FRUCTOSE BISPHOSPHATE ALDOLASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BINDING; GENE DUPLICATION; GENE SEQUENCE; HYDROPHOBICITY; MOLECULAR CLONING; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, CATALYTIC; BINDING SITES; CELL LINE; CLONING, MOLECULAR; EVOLUTION, MOLECULAR; FRUCTOSE-BISPHOSPHATE ALDOLASE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 12944317155     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.8.3878     Document Type: Article

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