Broadening the aldolase catalytic antibody repertoire by combining reactive immunization and transition state theory: New enantio- and diastereoselectivities

Angewandte Chemie - International Edition

Volumn 38, Issue 24, 1999, Pages 3738-3741

  Zhong, Guofu ^a   Lerner, Richard A ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Aldol reactions; Asymmetric synthesis; Catalytic antibodies; Enantiomeric resolution; Retro reactions

Indexed keywords

CATALYTIC ANTIBODY; FRUCTOSE BISPHOSPHATE ALDOLASE; HAPTEN;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DIASTEREOISOMER; ENANTIOMER; IMMUNIZATION; REACTION ANALYSIS; STEREOCHEMISTRY; THEORY;

EID: 0033576651     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991216)38:24<3738::AID-ANIE3738>3.0.CO;2-2     Document Type: Article

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