Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 26, 1998, Pages 15351-15355

  List, Benjamin ^a   Barbas III, Carlos F ^a   Lerner, Richard A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; DIKETONE; ENZYME; FRUCTOSE BISPHOSPHATE ALDOLASE;

ARTICLE; CATALYSIS; FLUORESCENCE; PRIORITY JOURNAL; REPORTER GENE; SENSOR; SYNTHESIS;

ALDEHYDES; ANTIBODIES, CATALYTIC; BIOSENSING TECHNIQUES; CATALYSIS; FLUORESCENT DYES; FRUCTOSE-BISPHOSPHATE ALDOLASE; IMMUNOGLOBULIN FAB FRAGMENTS; INDICATORS AND REAGENTS; KINETICS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0032416718     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.26.15351     Document Type: Article

References (19)

1. Haugland, R. P. (1996) Handbook of Fluorescent Probes and Research Chemicals (Molecular Probes, Eugene, OR), 6th Ed.
2. Tsien, R. Y. (1990) Annu. Rev. Biochem. 67, 509-544.
3. Wagner J., Lerner, R. A. & Barbas, C. F., III (1995) Science 270, 1797-1800.
4. Barbas, C. F., III, Heine, A., Zhong, G., Hoffmann, T., Gramatikova, S., Björnestedt, R., List, B., Anderson, J., Stura, E. A., Wilson, E. A. & Lerner, R. A. (1997) Science 278, 2085-2092.
5. Hoffmann, T., Zhong, G., List, B., Shabat, D., Anderson, J., Gramatikova, S., Lerner, R. A. & Barbas, C. F., III (1998) J. Am. Chem. Soc. 120, 2768-2779.
6. List, B., Shabat, D., Barbas, C. F., III, & Lerner, R. A. (1998) Chem. Eur. J. 4, 881-885.
7. Zhong, G., Shabat, D., List, B., Anderson, J., Sinha, S. C., Lerner, R. A. & Barbas, C. F., III (1998) Angew. Chem. Int. Ed. Engl. 37, 2481-2484.
8. Brown, H. C., Dhar, R. K., Ganesan, K. & Singaram, B. (1992) J. Org. Chem. 57, 499-504.
9. Weber, G. & Farris, J. F. (1997) Biochemistry 18, 3075-3078.
10. Cuvigny, T. & Normant, H. (1971) C. R. Hebd. Seances Acad. Sci. 272, 1425-1427.
11. Wierzchowski, J., Dafeldecker, W. P., Holmquist, B. & Vallee, B. L. (1989) Anal. Biochem. 178, 57-62.
12. Vallee, B. L. (1992) U.S. Patent 5,162,203.
13. Zlokarnik, G., Negulescu, P. A., Knapp, T. E., Mere, L., Burres, N., Feng, L., Whitney, M., Roemer, K. & Tsien, R. Y. (1998) Science 279, 84-88.
14. Klein, G. & Reymond, J.-L. (1998) Bioorg. Med. Chem. Lett. 8, 1113-1116.
15. Donate, M. T., Gomez-Lechon, M. J. & Castell, J. V. (1993) Anal. Biochem. 213, 29-33.
16. Behrens, A., Schirmer, K., Bols, N. C. & Segner, H. (1998) Mar. Environ. Res. 46, 369-373.
17. Mitsunobu, O. (1981) Synthesis 1-28.
18. Tsuji, J., Shimizu, I. & Yamamoto, K. (1976) Tetrahedron Lett. 34, 2975-2976.
19. Griffin, B. A., Adams, S. R. & Tsien, R. Y. (1998) Science 281, 269-272.