Lipid micelles stimulate the secretion of triglyceride-enriched apolipoprotein B48-containing lipoproteins by Caco-2 cells

Journal of Cellular Physiology

Volumn 202, Issue 3, 2005, Pages 767-776

  Chateau, Danielle ^a   Pauquai, Thomas ^a   Delers, François ^a   Rousset, Monique ^a   Chambaz, Jean ^a   Demignot, Sylvie ^a,b  

^a INSERM   (France)

^b U505 ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 OLEOYLGLYCEROL; APOLIPOPROTEIN B100; APOLIPOPROTEIN B48; CHOLESTEROL; FAT DROPLET; LEVO ALPHA LYSOPHOSPHATIDYLCHOLINE; LIPID; OLEIC ACID; SULFUR 35; TAUROCHOLIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ESTERIFICATION; FATTY ACID TRANSPORT; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE CELL; ISOTOPE LABELING; LIPOGENESIS; MICELLE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; ULTRACENTRIFUGATION;

APOLIPOPROTEIN B-48; APOLIPOPROTEINS B; CACO-2 CELLS; ENTEROCYTES; HUMANS; LIPID METABOLISM; LIPIDS; LIPOPROTEINS; MICELLES; TIME FACTORS; TRIGLYCERIDES;

EID: 12944259029     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20173     Document Type: Article

References (45)

1. Angermuller S, Fahimi HD. 1982. Imidazole-buffered osmium tetroxide: An excellent stain for visualization of lipids in transmission electron microscopy. Histochem J 14(5):823-835.
2. Boisfer E, Lambert G, Atger V, Tran NQ, Pastier D, Benetollo C, Trottier JF, Beaucamps I, Antonucci M, Laplaud M, Griglio S, Chambaz J, Kalopissis AD. 1999. Overexpression of human apolipoprotein A-II in mice induces hypertriglyceridemia due to defective very low density lipoprotein hydrolysis. J Biol Chem 274(17):11564-11572.
3. Buhman KK, Smith SJ, Stone SJ, Repa JJ, Wong JS, Knapp FF, Jr., Burri BJ, Hamilton RL, Abumrad NA, Farese RV, Jr. 2002. DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis. J Biol Chem 277(28):25474-25479.
4. Buschmann RJ, Manke DJ. 1981. Morphometric analysis of the membranes and organelles of small intestinal enterocytes. II. Lipid-fed hamster. J Ultrastruct Res 76(1):15-26.
5. Cartwright IJ, Higgins JA. 2001. Direct evidence for a two-step assembly of ApoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes. J Biol Chem 276(51):48048-48057.
6. Cartwright IJ, Plonne D, Higgins JA. 2000. Intracellular events in the assembly of chylomicrons in rabbit enterocytes. J Lipid Res 41(11):1728-1739.
7. Dannoura AH, Berriot-Varoqueaux N, Amati P, Abadie V, Verthier N, Schmitz J, Wetterau JR, Samson-Bouma ME, Aggerbeck LP. 1999. Anderson's disease: Exclusion of apolipoprotein and intracellular lipid transport genes. Arterioscler Thromb Vasc Biol 19(10):2494-2508.
8. Davidson NO, Shelness GS. 2000. Apolipoprotein B: mRNA editing, lipoprotein assembly, and presecretory degradation. Annu Rev Nutr 20:169-193.
9. Delie F, Rubas W. 1997. A human colonie cell line sharing similarities with enterocytes as a model to examine oral absorption: Advantages and limitations of the Caco-2 model. Crit Rev Ther Drug Carrier Syst 14(3):221-286.
10. Field FJ, Mathur SN. 1995. Intestinal lipoprotein synthesis and secretion. Prog Lipid Res 34(2):185-198.
11. Fielding PE, Fielding CJ. 2002. Dynamics of lipoprotein transport in the human circulatory system. In: Vance DE, Vance JE, editors. Biochemistry of lipids, lipoproteins, and membranes, 4th edn. Amsterdam: Elsevier. pp 527-552.
12. Fisher EA, Ginsberg HN. 2002. Complexity in the secretory pathway: The assembly and secretion of apolipoprotein B-containing lipoproteins. J Biol Chem 277(20):17377-17380.
13. Gotto AM, Jr., Pownall HJ, Havel RJ. 1986. Introduction to the plasma lipoproteins. Methods Enzymol 128:3-41.
14. Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K. 2002. Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction. J Biol Chem 277(35):31646-31655.
15. Hamilton RL, Wong JS, Cham CM, Nielsen LB, Young SG. 1998. Chylomicronsized lipid particles are formed in the setting of apolipoprotein B deficiency. J Lipid Res 39(8):1543-1557.
16. Havel RJ, Eder HA, Bragdon JH. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34(9):1345-1353.
17. Hernell O, Staggers JE, Carey MC. 1990. Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry 29(8):2041-2056.
18. Homan R, Hamelehle KL. 1998. Phospholipase A2 relieves phosphatidylcholine inhibition of micellar cholesterol absorption and transport by human intestinal cell line Caco-2. J Lipid Res 39(6):1197-1209.
19. Hussain MM, Kedees MH, Singh K, Athar H, Jamali NZ. 2001. Signposts in the assembly of chylomicrons. Front Biosci 6:D320-D331.
20. Jones B, Jones EL, Bonney SA, Patel HN, Mensenkamp AR, Eichenbaum-Voline S, Rudling M, Myrdal U, Annesi G, Naik S, Meadows N, Quattrone A, Islam SA, Naoumova RP, Angelin B, Infante R, Levy E, Roy CC, Freemont PS, Scott J, Shoulders CC. 2003. Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Nat Genet 34(1):29-31.
21. Kendrick JS, Chan L, Higgins JA. 2001. Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: An investigation of apobec-1 knock-out and wild-type mice. Biochem J 356(Pt 3):821-827.
22. Kulinski A, Rustaeus S, Vance JE. 2002. Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation. J Biol Chem 277(35):31516-31525.
23. Le Beyec J, Delers F, Jourdant F, Schreider C, Chambaz J, Cardot P, Pincon-Raymond M. 1997. A complete epithelial organization of Caco-2 cells induces I-FABP and potentializes apolipoprotein gene expression. Exp Cell Res 236(1): 311-320.
24. Levin MS, Talkad VD, Gordon JI, Stenson WF. 1992. Trafficking of exogenous fatty acids within Caco-2 cells. J Lipid Res 33(1):9-19.
25. Liao W, Chan L. 2000. Apolipoprotein B, a paradigm for proteins regulated by intracellular degradation, does not undergo intracellular degradation in CaCo2 cells. J Biol Chem 275(6):3950-3956.
26. Luchoomun J, Hussain MM. 1999. Assembly and secretion of chylomicrons by differentiated Caco-2 cells. Nascent triglycerides and preformed phospholipids are preferentially used for lipoprotein assembly. J Biol Chem 274(28):19565-19572.
27. Mathur SN, Born E, Murthy S, Field FJ. 1997. Microsomal triglyceride transfer protein in CaCo-2 cells: Characterization and regulation. J Lipid Res 38(1):61-67.
28. Moberly JB, Cole TG, Alpers DH, Schonfeld G. 1990. Oleic acid stimulation of apolipoprotein B secretion from HepG2 and Caco-2 cells occurs posttranscriptionally. Biochim Biophys Acta 1042(1):70-80.
29. Morel E, Demignot S, Chateau D, Chambaz J, Rousset M, Delers F. 2004. Lipid-dependent bidirectional traffic of apolipoprotein B in polarized enterocytes. Mol Biol Cell 15(1):132-141.
30. Murphy DJ, Vance J. 1999. Mechanisms of lipid-body formation. Trends Biochem Sci 24(3):109-115.
31. Olofsson SO, Asp L, Boren J. 1999. The assembly and secretion of apolipoprotein B-containing lipoproteins. Curr Opin Lipidol 10(4):341-346.
32. Olofsson SO, Stillemark-Billton P, Asp L. 2000. Intracellular assembly of VLDL: Two major steps in separate cell compartments. Trends Cardiovasc Med 10(8): 338-345.
33. Raabe M, Veniant MM, Sullivan MA, Zlot CH, Bjorkegren J, Nielsen LB, Wong JS, Hamilton RL, Young SG. 1999. Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest 103(9):1287-1298.
34. Ranheim T, Gedde-Dahl A, Rustan AC, Drevon CA. 1994. Fatty acid uptake and metabolism in CaCo-2 cells: Eicosapentaenoic acid (20:5(n-3)) and oleic acid (18:1(n-9)) presented in association with micelles or albumin. Biochim Biophys Acta 1212(3):295-304.
35. Robertson MD, Parkes M, Warren BF, Ferguson DJ, Jackson KG, Jewell DP, Frayn KN. 2003. Mobilisation of enterocyte fat stores by oral glucose in humans. Gut 52(6):834-839.
36. Sabesin SM, Frase S. 1977. Electron microscopic studies of the assembly, intracellular transport, and secretion of chylomicrons by rat intestine. J Lipid Res 18(4):496-511.
37. Schneider WJ. 2002. Lipoprotein receptors. In: Vance DE, Vance JE, editors. Biochemistry of lipids, lipoproteins, and membranes, 4th edn. Amsterdam: Elsevier. pp 553-572.
38. Shelness GS, Sellers JA. 2001. Very-low-density lipoprotein assembly and secretion. Curr Opin Lipidol 12(2):151-157.
39. Traber MG, Kayden HJ, Rindler MJ. 1987. Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line. J Lipid Res 28(11):1350-1363.
40. Trotter PJ, Storch J. 1993. Fatty acid esterification during differentiation of the human intestinal cell line Caco-2. J Biol Chem 268(14):10017-10023.
41. Tso P. 1994. Intestinal lipid absorption. In: Johnson LR, editor. Physiology of the gastrointestinal tract. New York: Raven press. pp 1867-1907.
42. van Greevenbroek MM, Voorhout WF, Erkelens DW, van Meer G, de Bruin TW. 1995. Palmitic acid and linoleic acid metabolism in Caco-2 cells: Different triglyceride synthesis and lipoprotein secretion. J Lipid Res 36(1):13-24.
43. van Greevenbroek MM, Robertus-Teunissen MG, Erkelens DW, de Bruin TW. 1998. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: Interaction with saturated and unsaturated dietary fatty acids. J Lipid Res 39(1):173-185.
44. van Meer G. 2001. Caveolin, cholesterol, and lipid droplets? J Cell Biol 152(5): F29-F34.
45. Vance JE. 2002. Assembly and secretion of lipoproteins. In: Vance DE, Vance JE, editors. Biochemistry of lipids, lipoproteins, and membranes, 4th edn. Amsterdam: Elsevier. pp 505-526.