Caveolin, cholesterol, and lipid droplets?

Journal of Cell Biology

Volumn 152, Issue 5, 2001, Pages

  Van Meer, Gerrit ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN; CHOLESTEROL; FAT DROPLET;

CELL MEMBRANE; CELL METABOLISM; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; ENERGY CONSERVATION; NOTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0035809929     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.152.5.F29     Document Type: Note

References (44)

1. Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol
2. Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes
3. Transbilayer movement of cholesterol in the human erythrocyte membrane
4. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein
5. The lipolytic stimulation of 3T3-L1 adipocytes promotes the translocation of hormone-sensitive lipase to the surfaces of lipid storage droplets
6. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
7. Structure and function of sphingolipid- and cholesterol-rich membrane rafts
8. Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
9. Transmembrane molecular pump activity of Niemann-Pick C1 protein
10. Hepatic lipid droplets. Isolation, morphology and composition
11. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae
12. Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2
13. High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts
14. Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell
15. ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine
16. Adipocyte differentiation related protein is secreted into milk as a constituent of milk lipid globule membrane
17. ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane
18. Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
19. Human acyl-CoA: Cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains
20. Intracellular cholesterol transport
21. Perilipin: Unique proteins associated with intracellular neutral lipid droplets in adipocytes and steroidogenic cells
22. Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells
23. VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro
24. Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol
25. Mechanism of the stimulatory action of okadaic acid on lipolysis in rat fat cells
26. VIP21/caveolin is a cholesterol-binding protein
27. Mechanisms of lipid-body formation
28. Caveolin interaction with protein kinase C. Isoenzyme-dependent regulation of kinase activity by the caveolin scaffolding domain peptide
29. Peroxisomal protein targeting and identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes
30. Accumulation of caveolin-1 in the endoplasmic reticulum redirects the protein to lipid storage droplets
31. Mechanism and consequences of cellular cholesterol exchange and transfer
32. A caveolin dominant-negative mutant associates with lipid bodies on the caveolin cycling pathway and induces intracellular cholesterol imbalance
33. Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: Triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures
34. Activated protein kinase C isoforms target to cardiomyocyte caveolae: Stimulation of local protein phosphorylation
35. Perilipins are associated with cholesteryl ester droplets in steroidogenic adrenal cortical and Leydig cells
36. Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3 L1 adipocytes
37. Lipotransin: A novel docking protein for hormone-sensitive lipase
38. Characterization of a cytosolic heat-shock protein caveolin chaperone complex. Involvement in cholesterol trafficking
39. Palmitoylation of caveolin-1 is required for cholesterol binding, chaperone complex formation, and rapid transport of cholesterol to caveolae
40. TIP47 associates with lipid droplets
41. Co-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies
42. Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells
43. Isolation and biochemical characterization of organelles from the yeast
44. Intracellular lipid particles of eukaryotic cells