Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells

Journal of Neuroscience

Volumn 25, Issue 3, 2005, Pages 748-757

  Yuan, Liya ^a   Kawada, Mariko ^a   Havlioglu, Necat ^b   Tang, Hao ^a   Wu, Jane Y ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Autosomal dominant retinitis pigmentosa (adRP); pre mRNA splicing; PRPF31; Retinal cells; Rhodopsin

Indexed keywords

MUTANT PROTEIN; RHODOPSIN; RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CELL DEATH; CONTROLLED STUDY; GENE MUTATION; IMMUNOPRECIPITATION; IN VIVO STUDY; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA CELL; RETINITIS PIGMENTOSA; RNA SPLICING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; EYE PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MICE; MUTATION; NEURONS; RETINA; RETINITIS PIGMENTOSA; RHODOPSIN; RNA SPLICING;

EID: 12744278348     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2399-04.2005     Document Type: Article

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