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Volumn 63, Issue 2, 2003, Pages 409-418

Maurotoxin: A potent inhibitor of intermediate conductance Ca2+-activated potassium channels

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; APAMIN; CALCIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL; IODINE 125; MAUROTOXIN; RUBIDIUM 86; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 0037308774     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.2.409     Document Type: Article
Times cited : (89)

References (32)
  • 1
    • 0029989851 scopus 로고    scopus 로고
    • The signature sequence of voltage-gated potassium channels projects into the external vestibule
    • Aiyar J, Rizzi JP, Gutman GA, and Chandy KG (1996) The signature sequence of voltage-gated potassium channels projects into the external vestibule. J Biol Chem 271:31013-31016.
    • (1996) J Biol Chem , vol.271 , pp. 31013-31016
    • Aiyar, J.1    Rizzi, J.P.2    Gutman, G.A.3    Chandy, K.G.4
  • 4
    • 0030783712 scopus 로고    scopus 로고
    • Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels
    • Blanc E, Sabatier JM, Kharrat R, Meunier S, el Ayeb M, Van Rietschoten J, and Darbon H (1997) Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels. Proteins 29:321-333.
    • (1997) Proteins , vol.29 , pp. 321-333
    • Blanc, E.1    Sabatier, J.M.2    Kharrat, R.3    Meunier, S.4    El Ayeb, M.5    Van Rietschoten, J.6    Darbon, H.7
  • 5
    • 0027331578 scopus 로고
    • PKA-dependent regulation of mKv1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells
    • Bosma MM, Allen ML, Martin TM, and Tempel BL (1993) PKA-dependent regulation of mKv1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells. J Neurosci 13:5242-5250.
    • (1993) J Neurosci , vol.13 , pp. 5242-5250
    • Bosma, M.M.1    Allen, M.L.2    Martin, T.M.3    Tempel, B.L.4
  • 6
    • 0027468927 scopus 로고
    • + transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins
    • + transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins. J Biol Chem 268, 8760-8768.
    • (1993) J Biol Chem , vol.268 , pp. 8760-8768
    • Brugnara, C.1    De Franceschi, L.2    Alper, S.L.3
  • 7
    • 0034944952 scopus 로고    scopus 로고
    • Molecular properties and physiological roles of ion channels in the immune system
    • Cahalan MD, Wulff H, and Chandy KG (2001) Molecular properties and physiological roles of ion channels in the immune system. J Clin Immunol 21:235-252.
    • (2001) J Clin Immunol , vol.21 , pp. 235-252
    • Cahalan, M.D.1    Wulff, H.2    Chandy, K.G.3
  • 9
    • 0012937117 scopus 로고    scopus 로고
    • Recent advances in the biology of small conductance calciumactivated potassium channels
    • Darbon H and Sabatier J-M eds, ppKluwer Academic Publishers, Dordrecht
    • Castle NA (1999) Recent advances in the biology of small conductance calciumactivated potassium channels, in Perspectives in Drug Discovery and Design: Animal Toxins and Potassium Channels (Darbon H and Sabatier J-M eds), Vol. 15/16, pp 131-154, Kluwer Academic Publishers, Dordrecht.
    • (1999) Perspectives in Drug Discovery and Design: Animal Toxins and Potassium Channels , vol.15-16 , pp. 131-154
    • Castle, N.A.1
  • 10
    • 4244078732 scopus 로고    scopus 로고
    • Maurotoxin - A potent inhibitor of the intermediate conductance calcium-activated potassium channel IK1
    • Castle NA, Creech C, and Sabatier J-M (2001) Maurotoxin - a potent inhibitor of the intermediate conductance calcium-activated potassium channel IK1 (Abstract). Biophys J 80:205a.
    • (2001) Biophys J , vol.80
    • Castle, N.A.1    Creech, C.2    Sabatier, J.-M.3
  • 11
    • 0025924134 scopus 로고
    • + channel from human erythrocyte membranes: Single channel rectification and selectivity
    • + channel from human erythrocyte membranes: single channel rectification and selectivity. J Membr Biol 119:75-83.
    • (1991) J Membr Biol , vol.119 , pp. 75-83
    • Christophersen, P.1
  • 13
    • 0034607464 scopus 로고    scopus 로고
    • Synthesis, 1H NMR structure and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins
    • Fajloun Z, Ferrat G, Carlier E, Fathallah M, Lecomte C, Sandoz G, di Luccio E, Mabrouk K, Legros C, Darbon H, et al. (2000a) Synthesis, 1H NMR structure and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins. J Biol Chem 275:13605-13612.
    • (2000) J Biol Chem , vol.275 , pp. 13605-13612
    • Fajloun, Z.1    Ferrat, G.2    Carlier, E.3    Fathallah, M.4    Lecomte, C.5    Sandoz, G.6    Di Luccio, E.7    Mabrouk, K.8    Legros, C.9    Darbon, H.10
  • 15
    • 0035184148 scopus 로고    scopus 로고
    • Potassium channels: From scorpion venoms to high-resolution structure
    • Garcia ML, Gao Y, McManus OB, and Kaczorowski GJ (2001) Potassium channels: from scorpion venoms to high-resolution structure. Toxicon 39:739-748.
    • (2001) Toxicon , vol.39 , pp. 739-748
    • Garcia, M.L.1    Gao, Y.2    McManus, O.B.3    Kaczorowski, G.J.4
  • 16
    • 0027320629 scopus 로고
    • Purification, characterization and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels
    • Garcia-Calvo M, Leonard RJ, Novick J, Stevens SP, Schmalhofer W, Kaczcrowski GJ, and Garcia ML (1993) Purification, characterization and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels. J Biol Chem 268:18866-18874.
    • (1993) J Biol Chem , vol.268 , pp. 18866-18874
    • Garcia-Calvo, M.1    Leonard, R.J.2    Novick, J.3    Stevens, S.P.4    Schmalhofer, W.5    Kaczcrowski, G.J.6    Garcia, M.L.7
  • 17
    • 0034711234 scopus 로고    scopus 로고
    • Up-regulation of the IKCA1 potassium channel during T-cell activation. Molecular mechanism and functional consequences
    • Ghanshani S, Wulff H, Miller MJ, Rohm H, Neben A, Gutman GA, Cahalan MD, and Chandy KG (2000) Up-regulation of the IKCA1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. J Biol Chem 275:37137-37149.
    • (2000) J Biol Chem , vol.275 , pp. 37137-37149
    • Ghanshani, S.1    Wulff, H.2    Miller, M.J.3    Rohm, H.4    Neben, A.5    Gutman, G.A.6    Cahalan, M.D.7    Chandy, K.G.8
  • 18
    • 0030865332 scopus 로고    scopus 로고
    • Determinants of apamin and dtubocurarine block in SK potassium channels
    • Ishii TM, Maylie J, and Adelman JP (1997a) Determinants of apamin and dtubocurarine block in SK potassium channels. J Biol Chem 272:23195-23200.
    • (1997) J Biol Chem , vol.272 , pp. 23195-23200
    • Ishii, T.M.1    Maylie, J.2    Adelman, J.P.3
  • 26
    • 0031455164 scopus 로고    scopus 로고
    • A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes
    • Logsdon NJ, Kang J, Togo JA, Christian EP, and Aiyar J (1997) A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes. J Biol Chem 272:32723-32726.
    • (1997) J Biol Chem , vol.272 , pp. 32723-32726
    • Logsdon, N.J.1    Kang, J.2    Togo, J.A.3    Christian, E.P.4    Aiyar, J.5
  • 29
    • 0030063883 scopus 로고    scopus 로고
    • T cell activation is regulated by voltage-dependent and calcium-activated potassium channels
    • Rader RK, Kahn LE, Anderson GD, Martin CL, Chinn KS, and Gregory SA (1996) T cell activation is regulated by voltage-dependent and calcium-activated potassium channels. J Immunol 156:1425-1430.
    • (1996) J Immunol , vol.156 , pp. 1425-1430
    • Rader, R.K.1    Kahn, L.E.2    Anderson, G.D.3    Martin, C.L.4    Chinn, K.S.5    Gregory, S.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.