Differentiated thick ascending limb (TAL) cultured cells derived from SV40 transgenic mice express functional apical NHE2 isoform: Effect of nitric oxide

Pflugers Archiv European Journal of Physiology

Volumn 446, Issue 6, 2003, Pages 672-683

  Bourgeois, Soline ^a   Rossignol, Patrick ^a   Grelac, Françoise ^a   Chalumeau, Cécile ^a   Klein, Christophe ^a   Laghmani, Kamel ^a   Chambrey, Régine ^a   Bruneval, Patrick ^a,b   Duong, Jean Paul ^a,b   Poggioli, Josiane ^a   Houillier, Pascal ^a,b   Paillard, Michel ^a,b   Kellermann, Odile ^c   Froissart, Marc ^a,b  

^a INSERM   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c CNRS   (France)

Author keywords

Cell culture; Ion transport; Kidney; Nitric oxide; Sodium hydrogen antiporter

Indexed keywords

COTRANSPORTER; NITRIC OXIDE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APICAL MEMBRANE; ARTICLE; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; GENE EXPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIMIAN VIRUS 40; TRANSGENIC MOUSE; VIRUS RECOMBINANT;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BIOTIN; CELLS, CULTURED; CHLORIDE-BICARBONATE ANTIPORTERS; DOWN-REGULATION; FEMALE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; ISOENZYMES; KIDNEY TUBULES; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; NITRIC OXIDE; NITRIC OXIDE DONORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM-HYDROGEN ANTIPORTER; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; TIGHT JUNCTIONS;

EID: 12444300792     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1108-x     Document Type: Article

References (52)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
2. Amemiya M, Loffing J, Lotscher M, Kaissling B, Alpern RJ, Moe OW (1995) Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int 48:1206-1215
3. + exchanger mRNAs in rat medullary thick ascending limb. Am J Physiol 268:F1224-F1228
4. Buc-Caron MH, Launay JM, Lamblin D, Kellermann O (1990) Serotonin uptake, storage, and synthesis in an immortalized committed cell line derived from mouse teratocarcinoma. Proc Natl Acad Sci USA 87:1922-1926
5. + exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. Am J Physiol 277:C1111-C1121
6. + exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation. Am J Physiol 281:C2039-C2048
7. Chalumeau C, Lamblin D, Bourgeois S, Borensztein P, Chambrey R, Bruneval P, Duong Van Huyen JP, Biber J, Froissart M, Paillard M, Kellermann O, Poggioli J (1999) Kidney cortical cells derived from SV40 transgenic mice retain properties of polarized proximal tubule cells. Kidney Int 56:559-570
8. + exchanger isoform NHE2 in rat kidney. Am J Physiol 275:F379-F386
9. + exchanger isoform NHE4 in rat thick ascending limbs. Am J Physiol 281:F707-F717
10. Choi JY, Shah M, Lee MG, Schultheis PJ, Shull GE, Muallem S, Baum M (2000) Novel amiloride-sensitive sodium-dependant proton secretion in the mouse proximal convoluted tubule. J Clin Invest 105:1141-1146
11. + antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties. Mol Pharmacol 44:1041-1045
12. - cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J Biol Chem 269:25677-25683
13. Eveloff J, Haase W, Kinne R (1980) Separation of renal medullary cells: isolation of cells from the thick ascending limb of Henle's loop. J Cell Biol 87:672-681
14. Garvin JL, Hong NJ (1999) Nitric oxide inhibits sodium/ hydrogen exchange activity in the thick ascending limb. Am J Physiol 277:F377-F382
15. Gill RK, Saksena S, Syed IA, Tyagi S, Alrefai WA, Malakooti J, Ramaswamy K, Dudeja PK (2002) Regulation of NHE3 by nitric oxide in Caco-2 cells. Am J Physiol 283:G747-G756
16. + exchangers. Proc Natl Acad Sci USA 92:12525-12529
17. + exchanger isoform NHE8. Am J Physiol 284:F467-F473
18. + antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanism. J Biol Chem 267:23823-23828
19. Igarashi P, Vanden Heuvel GB, Payne JA, Forbush Br (1995) Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol 269:F405-F418
20. + exchanger isoform 3 in human colon adenocarcinoma cell line Caco-2. Protein kinase C-mediated inhibition of the exchanger. J Biol Chem 273:8790-8798
21. + exchanger (NHE3) in three clones of caco-2 cells. Am J Physiol 277:G292-G305
22. Keil A, Blom IE, Goldschmeding R, Rupprecht HD (2002) Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells. Kidney Int 62:401-411
23. Kellermann O, Kelly F (1986) Immortalization of early embryonic cell derivatives after the transfer of the early region of simian virus 40 into F9 teratocarcinoma cells. Differentiation 32:74-81
24. Kellermann O, Buc-Caron MH, Gaillard J (1987) Immortalization of precursors of endodermal, neuroectodermal and mesodermal lineages, following the introduction of the simian virus (SV40) early region into F9 cells. Differentiation 35:197-205
25. Kovacs G, Peti-Peterdi J, Rosivall L, Bell PD (2002) Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors. Am J Physiol 282: F301-F306
26. Laghmani K, Borensztein P, Ambühl P, Froissart M, Bichara M, Moe OW, Alpern RJ, Paillard M (1997) Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA. J Clin Invest 99:24-30
27. Laghmani K, Richer C, Borensztein P, Paillard M, Froissart M (2001) Expression of rat thick limb Na/H exchangers in potassium depletion and chronic metabolic acidosis. Kidney Int 60:1386-1396
28. + channel, ROMK. Am J Physiol 275:F972-F981
29. + exchanger isoforms (NHE1 and NHE3) in polarized epithelial cell lines. J Cell Sci 109:929-939
30. Orlowski J (1993) Heterologous expression and functional properties of amiloride high affinity (NHE1) and low affinity (NHE3) isoforms of the rat Na/H exchanger. J Biol Chem 268:16369-16377
31. - cotransporter activity. Am J Physiol 281:F819-F825
32. - transporters in the medullary thick ascending limb of the kidney: molecular mechanisms, function and regulation. Kidney Int 53 (Suppl 65):S36-S41
33. Peti Peterdi J, Bell P (1998) Regulation of macula densa Na:H exchange by angiotensin II. Kidney Int 54:2021-2028
34. + exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms. Am J Physiol 278:F452-F463
35. Plato CF, Stoos BA, Wang D, Garvin JL (1999) Endogenous nitric oxide inhibits chloride transport in the thick ascending limb. Am J Physiol 276:F159-F163
36. Poliard A, Nifuji A, Lamblin D, Plee E, Forest C, Kellermann O (1995) Controlled conversion of an immortalized mesodermal progenitor cell towards osteogenic, chondrogenic, or adipogenic pathways. J Cell Biol 130:1461-1472
37. 3 transport in renal tubules. Kidney Int 39:1077-1086
38. + exchangers NHE2 and NHE3 in rat intestine and human Caco-2/bbe cells. Am J Physiol 280:C1224-C1232
39. Ross R, Kleinz R, Reske-Kunz AB (1995) A method for rapid generation of competitive standard molecules for RT-PCR avoiding the problem of competitor/probe cross-reaction. PCR Methods Applications 4:371-375
40. + antiporter, a glycoprotein of 110 kD. Science 247:723-726
41. Schnermann J, Briggs JP, McNicholas CM, MacGregor GG, Islas LD, Yang Y, Hebert SC, Giebisch G (1999) The macula densa is worth its salt. J Clin Invest 104:1007-1009
42. Scholz W, Albus U, Counillon L, Gogelein H, Lang HJ, Linz W, Weichert A, Scholkens BA (1995) Protective effects of HOE642, a selective sodium hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. Cardiovasc Res 29:260-268
43. + exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. J Clin Invest 101:1243-1253
44. Scott DM, Zierold K, Kinne R (1986) Development of differentiated characteristics in cultured kidney (thick ascending loop of Henle) cells. Exp Cell Res 162:521-529
45. Stoos BA, Naray-Fejes-Toth A, Carretero OA, Ito S, Fejes-Toth G (1991) Characterization of a mouse cortical collecting duct cell line. Kidney Int 39:1168-1175
46. - exchanger in the basolateral membrane of mouse medullary thick ascending limb. Am J Physiol 274: F358-F364
47. Thomson SC, Bachmann S, Bostanjoglo M, Ecelbarger CA, Peterson OW, Schwartz D, Bao D, Blantz RC (1999) Temporal adjustment of the juxtaglomerular apparatus during sustained inhibition of proximal reabsorption. J Clin Invest 104:1149-1158
48. Tournois C, Mutel V, Manivet P, Launay JM, Kellermann O (1998) Cross-talk between 5-hydroxytryptamine receptors in a serotonergic cell line. Involvement of arachidonic acid metabolism. J Biol Chem 273:17498-17503
49. Valentich JD, Stokols MF (1986) An established cell line from mouse kidney medullary thick ascending limb. I. Cell culture techniques, morphology, and antigenic expression. Am J Physiol 251:C299-C311
50. Wang T, Hropot M, Aronson P, Giebisch G (2001) Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. Am J Physiol 281:F1117-F1122
51. Wilcox C, Welch W, Murad F, Gross S, Taylor G, Levi R, Schmidt H (1992) Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci USA 89:11993-11997
52. Yu FH, Shull GE, Orlowski J (1993) Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells. J Biol Chem 268:25536-25541