Immunolocalization of the Na+/H+ exchanger isoform NHE2 in rat kidney

American Journal of Physiology - Renal Physiology

Volumn 275, Issue 3 44-3, 1998, Pages

  Chambrey, Régine ^a   Warnock, David G ^b   Podevin, René Alexandre ^b   Bruneval, Patrick ^b   Mandet, Chantal ^b   Bélair, Marie France ^b   Bariéty, Jean ^b   Paillard, Michel ^b  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b NONE

Author keywords

Apical membrane; Sodium hydrogen exchanger

Indexed keywords

ANTIPORTER; PROTON; SODIUM ION;

ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CONTROLLED STUDY; KIDNEY TUBULE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTON SODIUM EXCHANGE; RAT;

EID: 0031702752     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1998.275.3.f379     Document Type: Article

References (30)

1. Ambühl, P., M. Amemiya, M. Danczkay, M. Löscher, B. Kaissling, O. W. Moe, P. Preisig, and R. J. Alpern. Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F917-F925, 1996.
2. Amemiya, M., J. Loffing, M. Lotscher, B. Kaissling, R. J. Alpern, and O. W. Moe. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int. 48: 1206-1215, 1995.
3. Attmane-Elakeb, A., R. Chambrey, M. Tsimaratos, F. Leviel, A. Blanchard, D. G. Warnock, M. Paillard, and R.-A. Podevin. Isolation and characterization of luminal and basolateral plasma membrane vesicles from the medullary thick ascending loop of Henle. Kidney Int. 50: 1051-1057, 1996.
4. + exchanger isoform of renal brush border. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F736-F742, 1993.
5. + exchanger isoform NHE-1 in rabbit kidney. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F833-F840, 1992.
6. Bookstein, C., M. W. Musch, A. DePaoli, Y. Xie, M. Villereal, M. C. Rao, and E. B. Chang. A unique sodium-hydrogen exchange isoform (NHE-4) of the inner medulla of the rat kidney is induced by hyperosmolarity. J. Biol. Chem. 269: 29704-29709, 1994.
7. + exchanger mRNAs in rat medullary thick ascending limb. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F1224-F1228, 1995.
8. + exchanger in rat renal cortical tubules. Am. J. Physiol. 273 (Cell Physiol. 42): C1064-C1074, 1997.
9. Chambrey, R., E. Comoy, and R.-A. Podevin. Subcellular localization of the formation of tri-iodothyronine in the rabbit renal proximal tubule. Cell. Physiol. Biochem. 3: 137-145, 1993.
10. +-ATPase in proximal tubule apical membranes from rats with chronic metabolic acidosis. J. Biol. Chem. 269: 3243-3250, 1994.
11. Custer, M., M. Lötscher, J. Biber, H. Murer, and B. Kaislling. Expression of Na-Pi cotransport in rat kidney: localization by RT-PCR and immunohistochemistry. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F767-F774, 1994.
12. Ghishan, F. K., S. Knobel, J. A. Barnard, and M. Breyer. Expression of a novel sodium-hydrogen exchanger in the gastrointestinal tract and kidney. J. Membr. Biol. 144: 267-271, 1995.
13. Hoogerwerf, W. A., S. C. Tsao, O. Devuyst, A. S. Levine, C. H. C. Yun, J. W. Yip, M. E. Cohen, P. D. Wilson, A. J. Lazenby, C.-M. Tse, and M. Donowitz. NHE-2 and NHE-3 are human and rabbit intestinal brush-border proteins. Am. J. Physiol. 270 (Gastrointest. Liver Physiol. 33): G29-G44, 1996.
14. Kaplan, M. R., M. D. Plotkin, W.-S. Lee, Z.-C. Xu, J. Lytton, and S. Hebert. Apical localization of the Na-K-Cl cotransporter, rBSC1, on rat thick ascending limbs. Kidney Int. 49: 40-47, 1996.
15. Kumar, S., and A. Muchmore. Tamm-Horsfall-uromodulin (1950-1990). Kidney Int. 37: 1395-1401, 1990.
16. Laemmli, U. K. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
17. Laghmani, K., P. Borensztein, P. Ambühl, M. Froissart, M. Bichara, O. W. Moe, R. J. Alpern, and M. Paillard. Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA. J. Clin. Invest. 99: 24-30, 1997.
18. Orlowski, J., R. A. Kandasamy, and G. E. Shull. Molecular cloning of putative members of the Na/H exchanger gene family. J. Biol. Chem. 267: 9331-9339, 1992.
19. Shimizu, T., K. Yoshitomi, M. Nakamura, and M. Imai. Site and mechanism of action of trichlormethiazide in rabbit distal nephron segments perfused in vitro. J. Clin. Invest. 82: 721-730, 1988.
20. + exchanger isoform 2 (NHE2) is expressed in the apical membrane of the medullary thick ascending limb. J. Membr. Biol. 160: 85-90, 1997.
21. Tam, J. P. Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. Proc. Natl. Acad. Sci. USA 85: 5409-5413, 1988.
22. + exchanger isoform (NHE-3). J. Biol. Chem. 267: 9340-9346, 1992.
23. + exchanger. EMBO J. 10: 1957-1967, 1991.
24. + exchanger-2 is an O-linked but not an N-linked sialoglycoprotein. Biochemistry 33: 12954-12961, 1994.
25. Wang, T., S. K. Agulian, G. Giebisch, and P. S. Aronson. Effects of formate and oxalate on chloride absorption in rat distal tubule. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F730-F736, 1993.
26. Wang, T., G. Giebisch, and P. S. Aronson. Role of NHE3 in mediating bicarbonate absorption in the rat proximal tubule (Abstract). J. Am. Soc. Nephrol. 8: 13, 1997.
27. Wang, T., G. Malnic, G. Giebisch, and Y. L. Chan. Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule. J. Clin. Invest. 91: 2776-2784, 1993.
28. Wang, Z., J. Orlowski, and G. E. Shull. Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger. J. Biol. Chem. 268: 11925-11928, 1993.
29. + exchange. J. Biol. Chem. 271: 32749-32752, 1996.
30. + exchanger isoform NHE-2 in rat kidney with confocal fluorescence microscopy. FASEB J. 10: A370, 1996.