Localization and functional characterization of NA+/H+ exchanger isoform NHE4 in rat thick ascending limbs

American Journal of Physiology - Renal Physiology

Volumn 281, Issue 4 50-4, 2001, Pages

  Chambrey, Régine ^a,d   St John, Patricia L ^b   Eladari, Dominique ^a   Quentin, Fabienne ^a   Warnock, David G ^c   Abrahamson, Dale R ^b   Podevin, René Alexandre ^a   Paillard, Michel ^a  

^a HÔPITAL BROUSSAIS   (France)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

Ammonium transport; Basolateral membrane vesicles; Kidney; Sodium hydrogen exchanger

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; AQUAPORIN 2; AQUAPORIN 3; COMPLEMENTARY DNA; HYDROGEN; ISOPROTEIN; POLYCLONAL ANTIBODY; SODIUM; TAMM HORSFALL GLYCOPROTEIN;

ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; DNA LIBRARY; HENLE LOOP; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY DISTAL TUBULE; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; MALE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTON SODIUM EXCHANGE; RAT;

EID: 0034796170     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.281.4.f707     Document Type: Article

References (52)

1. Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney
2. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
3. Expression of NHE1 and NHE4 in rat pancreatic zymogen granule membranes
4. + exchanger (NHE5) highly expressed in brain
5. Isolation and characterization of luminal and basolateral plasma membrane vesicles from the medullary thick ascending loop of Henle
6. + exchanger isoform of renal brush border
7. + exchanger isoform NHE-1 in rabbit kidney
8. Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney
9. + exchangers of thick ascending limbs of rat kidney: Evidence from isolated membranes
10. + exchanger isoform NHE4 and localization in rat hippocampus
11. A unique sodium-hydrogen exchange isoform (NHE-4) of the inner medulla of the rat kidney is induced by hyperosmolarity
12. + exchanger in rat renal cortical tubules
13. + exchanger isoform
14. + exchanger isoform NHE2 in rat kidney
15. + antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties
16. + exchanger in colon and is increased by a low-NaCl diet
17. Aquaporin-3 water channel localization and regulation in rat kidney
18. - exchangers of rat thick limbs
19. Polarized expression of different monocarboxylate transporters in rat medullary thick limbs of Henle
20. Ammonium replaces potassium in supporting sodium transport by the Na-K-ATPase of renal proximal straight tubules
21. Ammonia transport in the mammalian kidney
22. NHE2 and NHE3 are human and rabbit intestinal brush-border proteins
23. Tamm-Horsfall glycoprotein: Ultrastructural immunoperoxidase localization in rat kidney
24. Differential regulation of NHE isoforms by sodium depletion in proximal and distal segments of rat colon
25. + exchanger (NHE5/SLC9A5) to chromosome 16q22.1
26. Na/H antiporter MRNA expression in single nephron segments of rat kidney cortex
27. Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 MRNA
28. + exchangers stably expressed in a fibroblast cell line
29. + absorption in vivo
30. Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney
31. + exchanger
32. Expression of the thiazidesensitive Na-Cl cotransporter in rat and human kidney
33. Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger
34. Molecular cloning of putative members of the Na/H exchanger gene family. CDNA cloning, deduced amino acid sequence, and MRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins
35. + exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms
36. + exchanger isoform NHE4
37. Water and solute permeabilities of medullary thick ascending limb apical and basolateral membranes
38. + antiporter
39. Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion
40. Localization of Tamm-Horsfall glycoprotein in the normal rat kidney and the effect of adrenalectomy on its localization in the hamster and rat kidney
41. + exchanger isoform (NHE-3)
42. + exchanger (NHE3): Resistance to amiloride and inhibition by protein kinase C
43. + exchanger isoform (NHE-2)
44. + exchanger
45. + augments net acid secretion by a ouabain-sensitive mechanism in isolated perfused inner medullary collecting ducts
46. + transport in mouse inner medullary collecting duct cells
47. Effects of formate and oxalate on chloride absorption in rat distal tubule
48. Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule
49. Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger
50. + exchange
51. + exchange. Adaptation to metabolic acidosis
52. Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells