Protection against plague afforded by immunisation with DNA vaccines optimised for expression of the Yersinia pestis V antigen

Vaccine

Volumn 22, Issue 8, 2004, Pages 947-957

  Garmory, Helen S ^a   Freeman, Donna ^b   Brown, Katherine A ^c   Titball, Richard W ^a,d  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

^b Acambis   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

DNA vaccine; Plague; V antigen; Yersinia pestis

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL DNA; BACTERIAL VACCINE; DNA VACCINE; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG; V ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CODON; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA VECTOR; GENE GUN; GENETIC CODE; HUMORAL IMMUNITY; IMMUNOPROPHYLAXIS; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PLAGUE; PRIORITY JOURNAL; VACCINATION; YERSINIA PESTIS;

EID: 1242270647     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2003.09.020     Document Type: Article

References (49)

1. Perry R.D., Fetherstone J.D. Yersinia pestis-etiological agent of plague. Clin. Microbiol. Rev. 10:1997;35-66.
2. Titball R.W., Leary S.E.C. Plague. Br. Med. Bull. 54:1998;625-633.
3. World Health Organisation. Human plague in 1994. Wkly Epidemiol Rec 1996;71:165-72.
4. Inglesby T.V., Dennis D.T., Henderson D.A.et al. Plague as a biological weapon medical and public health management. JAMA. 283:2000;2281-2290.
5. Meyer K.F., Cavanaugh D.C., Bartelloni P.J., Marshall J.D. Jr. Plague immunization. I. Past and present trends. J. Infect. Dis. 129:1974;S13-S18.
6. Cavanaugh D.C., Elisberg B.L., Llewellyn C.H., Marshall J.D. Jr., Rust J.H. Jr., Williams J.E.et al. Plague immunization. V. Indirect evidence for the efficacy of plague vaccine. J. Infect. Dis. 129:1974;S37-40.
7. Williamson E.D., Eley S.M., Stagg A.J., Green M., Russell P., Titball R.W. A sub-unit vaccine elicits IgG in serum, spleen cell cultures and bronchial washings and protects immunized animals against pneumonic plague. Vaccine. 15:1997;1079-1084.
8. Cohen R.J., Stockard J.L. Pneumonic plague in an untreated plague-vaccinated individual. JAMA. 202:1967;356-365.
9. Marshall J.D. Jr., Bartelloni P.J., Cavanaugh D.C., Kadull P.J., Meyer K.F. Plague immunization. II. Relation of adverse clinical reactions to multiple immunizations with killed vaccine. J. Infect. Dis. 129:1974;S19-S25.
10. Heath D.G., Anderson G.W. Jr., Mauro J.M.et al. Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccine. Vaccine. 16:1998;1131-1137.
11. Williamson E.D., Eley S.M., Griffin K.F.et al. A new improved sub-unit vaccine for plague: the basis of protection. FEMS Immunol. Med. Microbiol. 12:1995;223-230.
12. Williamson E.D., Eley S.M., Stagg A.J., Green M., Russell P., Titball R.W. A sub-unit vaccine elicits IgG in serum, spleen cell cultures and bronchial washings and protects immunized animals against pneumonic plague. Vaccine. 15:1997;1079-1084.
13. Williamson E.D., Eley S.M., Stagg A.J., Green M., Russell P., Titball R.W. A single dose sub-unit vaccine protects against pneumonic plague. Vaccine. 19:2001;566-571.
14. Davis H.L. Plasmid DNA expression systems for the purpose of immunization. Curr. Opin. Biotechnol. 8:1997;635-640.
15. Lewis J.P., Babiuk L.A. DNA vaccines: a review. Adv. Virus Res. 54:1999;129-188.
16. Tang D.C., Devit M., Johnston S.A. Genetic immunization is a simple method for eliciting an immune response. Nature. 356:1992;152-154.
17. Bennett A.M., Phillpotts R.J., Perkins S.D., Jacobs S.C., Williamson E.D. Gene gun mediated vaccination is superior to manual delivery for immunisation with DNA vaccines expressing protective antigens from Yersinia pestis or Venezuelan Equine Encephalitis virus. Vaccine. 18:1999;588-596.
18. Galvin T.A., Muller J., Khan A.S. Effect of different promoters on immune responses elicited by HIV-1 gag/env multigenic DNA vaccine in Macaca mulatta and Macaca nemestrina. Vaccine. 18:2000;2566-2583.
19. Kwissa M., von Kampen J., Zurbriggen R., Gluck R., Reimann J., Schirmbeck R. Efficient vaccination by intradermal or intramuscular inoculation of plasmid DNA expressing hepatitis B surface antigen under desmin promoter/enhancer control. Vaccine. 18:2000;2337-2344.
20. Suarez D.L., Schultz-Cherry S. The effect of eukaryotic expression vectors and adjuvants on DNA vaccines in chickens using an avian influenza model. Avian Dis. 44:2000;861-868.
21. Van Drunen Little-van den Hurk S., Braun R.P., Lewis P.J.et al. Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle. J. Gen. Virol. 79:1998;831-839.
22. Watts A.M., Bright R.K., Kennedy R.C. DNA cancer vaccination strategies target SV40 large tumour antigen in a murine experimental metastasis model. Dev. Biol. (Basel). 104:2000;143-147.
23. Xiang Z.Q., Spitalnik S.L., Cheng J., Erikson J., Wojczyk B., Ertl H.C.J. Immune responses to nucleic acid vaccines to rabies virus. Virology. 209:1995;569-579.
24. Xu Z.-L., Mizuguchi H., Ishii-Watabe A., Uchida E., Mayumi T., Hayakawa T. Optimization of transcriptional regulatory elements for constructing plasmid vectors. Gene. 272:2001;149-156.
25. André S., Seed B., Erberle J., Schraut W., Bultmann A., Haas J. Increased immune response elicited by DNA vaccination with a synthetic gp 120 sequence with optimized codon usage. J. Virol. 72:1998;1497-1503.
26. Deml L., Bojak A., Steck S.et al. Multiple effects of codon usage optimization on expression and immunogenicity of DNA candidate vaccines encoding the human immunodeficiency virus type I gag protein. J. Virol. 75:2001;10991-11001.
27. Narum D.L., Kumar S., Rogers W.O.et al. Codon optimization of gene fragments encoding Plasmodium falciparum merzoite proteins enhances DNA vaccine protein expression and immunogenicity in mice. Infect. Immun. 69:2001;7250-7253.
28. Stratford R., Douce G., Zhang-Barber L., Fairweather N., Eskola J., Dougan G. Influence of codon usage on the immunogenicity of a DNA vaccine against tetanus. Vaccine. 19:2001;810-815.
29. Uchijima M., Yoshida A., Nagata T., Koide Y. Optimization of codon usage of plasmid DNA vaccine is required for the effective MHC class I restricted T cell responses against an intracellular bacterium. J. Immunol. 161:1998;5594-5599.
30. Vinner L., Nielsen H.V., Bryder K., Corbet S.L., Nielsen C., Fomsgaard A. Gene gun vaccination with rev-independent synthetic HIV-1 gp160 envelope gene using mammalian codons. Vaccine. 17:1999;2166-2175.
31. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. Cold Spring Harbour: Cold Spring Harbour Laboratory Press; 1989.
32. Stein I., Itin A., Einat P., Skaliter R., Grossman L., Keshet E. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia. Mol. Cell. Biol. 18:1998;3112-3119.
33. Mizushima S., Nagata S. PEF-BOS, a powerful mammalian expression vector. Nucl. Acids Res. 18:1990;5322.
34. Gorman C.M., Merlino G.T., Willingham M.C., Pastan I., Howard B.H. The rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. U.S.A. 79:1982;6777-6781.
35. Moreau P., Hen R., Wasylyk B., Everett E., Gaub M.P., Champon P. The SV40 72 base pair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucl. Acids Res. 9:1981;6047-6068.
36. Schorpp M., Jäger R., Schellander K.et al. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucl. Acids Res. 24:1996;1787-1788.
37. Roberts M., Li J., Bacon A., Chatfield S. Oral vaccination against tetanus: comparison of the immunogenicities of Salmonella strains expressing fragment C from the nirB and htrA promoters. Infect. Immun. 66:1998;3080-3087.
38. Kozak M. Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6. EMBO J. 16:1997;2482-2492.
39. Wada K.-N., Wada Y., Ishibashi F., Gojobori T., Ikemura T. Codon usage tabulated from the GenBank genetic sequence data. Nucl. Acids Res. 20:1992;2111-2118.
40. Hill J., Leary S.E.C., Griffin K.F., Williamson E.D., Titball R.W. Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunization. Infect. Immun. 65:1997;4476-4482.
41. Garmory H.S., Griffin K.F., Brown K.A., Titball R.W. Oral immunisation with live aroA attenuated serovar Typhimurium expressing the Yersinia pestis V antigen protects mice against plague. Vaccine. 21:2003;3051-3057.
42. Russell P., Eley S.M., Hibbs S.E., Stagg A.J., Titball R.W. A comparison of Plague vaccine, USP and EV76 vaccine induced protection against Y. pestis in a murine model. Vaccine. 13:1995;1551-1556.
43. Leary S.E.C., Williamson E.D., Griffin K.F., Russell P., Eley S.M., Titball R.W. Active immunization with recombinant V antigen from Yersinia pestis protects mice against plague. Infect. Immun. 63:1995;2854-2858.
44. Ikemura T. Codon usage ans tRNA content in unicellular and multicellular organisms. Mol. Biol. E. 2:1985;13-34.
45. Hale R.S., Thompson G. Codon optimization of the gene encoding a domain from human type 1 fibriomin protein results in a threefold improvement in expression levels in E. coli. Protein Expr. Purif. 12:1998;185-188.
46. Belperron A.A., Feltquate D., Fox B.A., Horii T., Bzik D.J. Immune responses induced by gene gun or intramuscular injection of DNA vaccines that express immunogenic regions of the serine repeat antigen from Plasmodium falciparum. Infect. Immun. 67:1999;5163-5169.
47. Fynan E.F., Webster R.G., Fuller D.H., Haynes J.R., Santoro J.C., Robinson H.L. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. U.S.A. 90:1993;11478-11482.
48. Yoshida A., Nagata T., Uchijima M., Higashi T., Koide Y. Advantage of gene gun-mediated over intramuscular inoculation of plasmid DNA in reproducible induction of specific immune responses. Vaccine. 18:2000;1725-1729.
49. Williamson E.D., Vesey P.M., Gillhespy K.J., Eley S.M., Green M., Titball R.W. An IgG1 titre to the F1 and V antigens correlates with protection against plague in the mouse model. Clin. Exp. Immunol. 116:1999;107-114.