Effect of different promoters on immune responses elicited by HIV-1 gag/env multigenic DNA vaccine in Macaca mulatta and Macaca nemestrina

Vaccine

Volumn 18, Issue 23, 2000, Pages 2566-2583

  Galvin, Teresa A ^a,c   Muller, Jacqueline ^b   Khan, Arifa S ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b Center for Biologics   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Human immunodeficiency virus type 1; Plasmid DNA vaccine; Promoter activity

Indexed keywords

DNA VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ANTIBODY RESPONSE; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MACACA; PLASMID; PRIORITY JOURNAL; VACCINATION;

EID: 0034701826     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(99)00569-1     Document Type: Article

References (50)

1. Baltimore D. Lessons from people with nonprogressive HIV infections. N. Engl. J. Med. 332:1995;259-260.
2. Haynes B.F., Pantaleo G., Fauci A.S. Toward an understanding of the correlates of protective immunity to HIV infection. Science. 271:1996;324-328.
3. Wang B., Ugen K.E., Srikantan V., Agadjanyan M.G., Dang K., Refaeli Y., Sato A.I., Boyer J., Williams W.V., Weiner D.B. Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc. Natl Acad. Sci. USA. 90:1993;4156-4160.
4. Fuller D.H., Haynes J.R. A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine. AIDS Res. Hum. Retroviruses. 10:1994;1433-1441.
5. Lu S., Santoro J.C., Fuller D.H., Haynes J.R., Robinson H.L. Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice. Virology. 209:1995;147-154.
6. Okuda K., Bukawa H., Hamajima K., Kawamoto S., Sekigawa K.-I., Yamada Y., Tanaka S.-I., Ishi N., Aoki I., Nakamura M., Yamamoto H., Cullen B.R., Fukushima J. Induction of potent humoral and cell-mediated immune responses following direct injection of DNA encoding the HIV type 1 env and rev gene products. AIDS Res. Hum. Retroviruses. 11:1995;933-943.
7. Shiver J.W., Perry H.C., Davies M.E., Freed D.C., Liu M.A. Cytotoxic T lymphocyte and helper T cell responses following HIV polynucleotide vaccination. Ann. NY Acad. Sci. 772:1995;198-208.
8. Wang B., Boyer J., Srikantan V., Ugen K., Gilbert L., Phan C., Dang K., Merva M., Agadjanyan M.G., Newman M., Carrano R., McCallus D., Coney L., Williams W.V., Weiner D.B. Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation. Virology. 211:1995;102-112.
9. Boyer J.D., Wang B., Ugen K.E., Agadjanyan M., Javadian A., Frost P., Dang K., Carrano R.A., Ciccarelli R., Coney L., Williams W.V., Weiner D.B. In vivo protective anti-HIV immune responses in non-human primates through DNA immunization. J. Med. Primatol. 25:1996;242-250.
10. Fuller D.H., Murphey-Corb M., Clements J., Barnett S., Haynes J.R. Induction of immunodeficiency virus-specific immune responses in rhesus monkeys following gene gun-mediated DNA vaccination. J. Med. Primatol. 25:1996;236-241.
11. Boyer J.D., Ugen K.E., Wang B., Agadjanyan M., Gilbert L., Bagarazzi M.L., Chattergoon M., Frost P., Javadian A., Williams W.V., Refaeli Y., Ciccarelli R.B., McCallus D., Coney L., Weiner D.B. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nature Med. 3:1997;526-532.
12. Fuller D.H., Murphey-Corb M., Barnett S., Steimer K., Haynes J.R. Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques. Vaccine. 15:1997;924-926.
13. Hinkula J., Lundholm P., Wahren B. Nucleic acid vaccination with HIV regulatory genes: a combination of HIV-1 genes in separate plasmids induces strong immune responses. Vaccine. 15:1997;874-878.
14. Letvin N.L., Montefiori D.C., Yasutomi Y., Perry H.C., Davies M.-E., Lekutis C., Alroy M., Freed D.C., Lord C.I., Handt L.K., Liu M.A., Shiver J.W. Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. Proc. Natl Acad. Sci. USA. 94:1997;9378-9383.
15. Robinson H.L., Montefiori D.C., Johnson R.P., Manson K.H., Kalish M.L., Lifson J.D., Rizvi T.A., Lu S., Hu S.-L., Mazzara G.P., Panicali D.L., Herndon J.G., Glickman R., Candido M.A., Lydy S.L., Wyand M.S., McClure H.M. Neutralizating antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunization. Nature Med. 5:1999;526-534.
16. Cheng L., Ziegelhoffer P.R., Yang N.-S. In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. Proc. Natl Acad. Sci. USA. 90:1993;4455-4459.
17. Davis H.L., Whalen R.G., Demeneix B.A. Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression. Hum. Gene Ther. 4:1993;151-159.
18. Manthorpe M., Cornefert-Jensen F., Hartikka J., Felgner J., Rundell A., Margalith M., Dwarki V. Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum. Gene Ther. 4:1993;419-431.
19. Raz E., Carson D.A., Parker S.E., Parr T.B., Abai A.M., Aichinger G., Gromkowski S.H., Singh M., Lew D., Yankauckas M.A., Baird S.M., Rhodes G.H. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl Acad. Sci. USA. 91:1994;9519-9523.
20. Böhm W., Kuhröber A., Paier T., Mertens T., Reimann J., Schirmbeck R. DNA vector constructs that prime hepatits B surface antigen-specific cytotoxic T lymphocyte and antibody responses in mice after intramuscular injection. J. Immunol. Methods. 193:1996;29-40.
21. Hayasaka K., Fujii K., Horai S. Molecular phylogeny of macaques: implications of nucleotide sequences from an 896-base pair region of mitochondrial DNA. Mol. Biol. Evol. 13:1996;1044-1053.
22. Khan A.S., Theodore T.S. Nucleotide sequence and functional analysis of the LTRs of endogenous ecotropic MuLV proviruses of AKR and BALB/C mice. Nucleic Acids Res. 15:1987;7640.
23. Laimins L.A., Gruss P., Pozzatti R., Khoury G. Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus. J. Virol. 49:1984;183-189.
24. Boshart M., Weber F., Jahn G., Dorsch-Haesler K., Fleckenstein B., Schaffner W. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell. 41:1985;521-530.
25. Ahmad N., Venkatesan S. Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR. Science. 241:1988;1481-1485.
26. Adachi A., Gendelman H.E., Koenig S., Folks T., Willey R., Rabson A., Martin M.A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and non human cells transfected with an infectious molecular clone. J. Virol. 59:1986;284-291.
27. Prince A.M., Horowitz B., Baker L., Schulman R.W., Ralph H., Valinsky J., Cundell A., Brotman B., Boehle W., Rey F., Piet M., Reesink H., Lelie N., Tersmette M., Miedema F., Barbosa L., Nemo G., Nastala C.L., Allan J.S., Lee D.R., Eichberg J.W. Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV. Proc. Natl Acad. Sci. USA. 85:1988;6944-6948.
28. Prince A.M., Reesink H., Pascual D., Horowitz B., Hewlett I., Murthy K.K., Cobb K.E., Eichberg J.W. Prevention of HIV infection by passive immunization with HIV immunoglobulin. AIDS Res. Hum. Retroviruses. 7:1991;971-973.
29. Hatch W.C., Tanaka K.E., Calvelli T., Rashbaum W.K., Kress Y., Lyman W.D. Persistent productive HIV-1 infection of a CD4-human fetal thymocyte line. J. Immunol. 148:1992;3055-3061.
30. Page K.A., Stearns S.M., Littman D.R. Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity. J. Virol. 66:1992;524-533.
31. Steimer K.S., Puma J.P., Power M.D., Powers M.A., George-Nascimento C., Stephans J.C., Levy J.A., Sanchez-Pescador R., Luciw P.A., Barr P.J., Hallewell R.A. Differential antibody responses of individuals infected with AIDS-associated retroviruses surveyed using the viral core antigen p25gag expressed in bacteria. Virology. 150:1986;283-290.
32. Abacioglu Y.H., Fouts T.R., Laman J.D., Claassen E., Pincus S.H., Moore J.P., Roby C.A., Kamin-Lewis R., Lewis G.K. Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies. AIDS Res. Hum. Retroviruses. 10:1994;371-381.
33. National Research Council. Guide for the care and use of laboratory animals. 1996;National Academy Press, Washington, DC.
34. Hope T.J., McDonald D., Huang X.J., Low J., Parslow T.G. Mutational analysis of human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus. J. Virol. 64:1990;5360-5366.
35. Dayton E.T., Powell D.M., Dayton A.I. Functional analysis of CAR, the target sequence for the Rev protein of HIV-1. Science. 246:1989;1625-1629.
36. Wright-Browne V., McClain K.L., Talpaz M., Ordonez N., Estrov Z. Physiology and pathopysiology of dendritic cells. Hum. Pathol. 28:1997;563-579.
37. Vogel J., Hinrichs S.H., Reynolds R.K., Luciw P.A., Jay G. The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature (London). 335:1988;606-611.
38. Kim C.M., Vogel J., Jay G., Rhim J.S. The HIV-1 tat gene transforms human keratinocytes. Oncogene. 7:1992;1525-1529.
39. Jowett J.B., Planelles V., Poon B., Shah N.P., Chen M.L., Chen I.S. The human immunodefiency virus type 1 vpr gene arrests infected T cells in the G2+M phase of the cell cycle. J. Virol. 69:1995;6304-6313.
40. Piller S.C., Jans P., Gage P.W., Jans D.A. Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology. Proc. Natl Acad. Sci. USA. 95:1998;4595-4600.
41. Garcia J.V., Miller A.D. Serine phophorylation-independent downregulation of cell-surface CD4 by nef. Nature. 350:1991;508-511.
42. Greenberg M.E., Iafrate A.J., Skowronski J. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17:1998;2777-2789.
43. Kestler H.W., Ringler D.J., Mori K., Panicali D.L., Sehgal P.K., Daniel M.D., Desrosiers R.C. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell. 65:1991;651-662.
44. Hanna Z., Kay D.G., Cool M., Jothy S., Rebai N., Jolicoeur P. Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease. J. Virol. 72:1998;121-132.
45. Coffin J.M. Molecular mechanisms of nucleic acid integration. J. Med. Virol. 31:1990;43-49.
46. Temin H.M. Overview of biological effects of addition of DNA molecules to cells. J. Med. Virol. 31:1990;13-17.
47. Silvestris F., Williams R.C., Dammacco F. Autoreactivity in HIV-1 infection: the role of molecular mimicry. Clin. Immunol. Immunopathol. 75:1995;197-205.
48. Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M.-D., Silverman G.J., Lotz M., Carson D.A., Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science. 273:1996;352-354.
49. Agy M.B., Frumkin L.R., Corey L., Coombs R.W., Wolinsky S.M., Koehler J., Morton W.R., Katze M.G. Infection of Macaca nemestrina by human immunodeficiency virus type-1. Science. 257:1992;103-106.
50. Gartner S., Liu Y., Lewis M.G., Polonis V., Elkins W.R., Zack P.M., Miao J., Hunter E.A., Greenhouse J., Eddy G.A. HIV-1 infection in pig-tailed macaques. AIDS Res. Hum. Retroviruses. 10:1994;S129-S133.