Catalytic carbometalation/cross-coupling sequence across alkynyl(2-pyridyl)silanes leading to a diversity-oriented synthesis of tamoxifen-type tetrasubstituted olefins

Advanced Synthesis and Catalysis

Volumn 346, Issue 13-15, 2004, Pages 1824-1835

  Kamei, Toshiyuki ^a   Itami, Kenichiro ^a   Yoshida, Jun Ichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Carbomagnesation; Cross coupling; Directing effect; Diversity oriented synthesis; Synthesis design; Tamoxifen

Indexed keywords

ALKENE DERIVATIVE; COPPER; IODIDE; SILANE DERIVATIVE; TAMOXIFEN;

ARTICLE; CATALYSIS; CROSS COUPLING REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

EID: 12344333388     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200404220     Document Type: Article

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