Flexible estrogen receptor modulators: Design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells

Journal of Medicinal Chemistry

Volumn 44, Issue 7, 2001, Pages 1072-1084

  Meegan, M J ^a   Hughes, R B ^a   Lloyd, D G ^a   Williams, D C ^a   Zisterer, D M ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; MATHEMATICAL ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL DIVISION; DRUG DESIGN; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; LIGANDS; MODELS, MOLECULAR; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; UTERUS;

EID: 0035966873     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001119l     Document Type: Article

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