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Volumn 40, Issue 17, 1999, Pages 3403-3406

2-pyridylsilyl group as a multifunctional 'phase tag' for solution phase synthesis

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRIDYLSILYL; ETHER; HYDROCHLORIC ACID; PYRIDINE DERIVATIVE; SILANE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0033597302     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00474-8     Document Type: Article
Times cited : (52)

References (39)
  • 24
    • 0013477445 scopus 로고    scopus 로고
    • For organo(2-pyridyl)dimethylsilane having polar funcitonal groups, the number of extraction would be decreased to two or three
    • (8) For organo(2-pyridyl)dimethylsilane having polar funcitonal groups, the number of extraction would be decreased to two or three.
  • 25
    • 0013549483 scopus 로고    scopus 로고
    • 3-Pyridyldimethylsilyl group was also found to be quite effective as a "phase tag" for acid-base extraction
    • (9) 3-Pyridyldimethylsilyl group was also found to be quite effective as a "phase tag" for acid-base extraction.
  • 28
    • 0013477939 scopus 로고    scopus 로고
    • In 1,2-dichloroethane 3-pyridyldimethylsilane gave the hydrosilylation product in 90% yield, although the reaction was still very slow (20 h)
    • (12) In 1,2-dichloroethane 3-pyridyldimethylsilane gave the hydrosilylation product in 90% yield, although the reaction was still very slow (20 h).
  • 29
    • 0013477940 scopus 로고
    • (13) For pyridylsilyl group coordination to the metal, see: (a) Jutzi, P.; Heusler, H. J. Organomet. Chem. 1975, 102, 145.
    • (1975) J. Organomet. Chem. , vol.102 , pp. 145
    • Jutzi, P.1    Heusler, H.2
  • 37
    • 0024829721 scopus 로고
    • (16) Pioneering work of Chan revealed that the aminomethylsilyl group is cleaved under 'standard conditions' of Tamao oxidation: Chan, T. H.; Pellon, P. J. Am. Chem. Soc. 1989, 111, 8737.
    • (1989) J. Am. Chem. Soc. , vol.111 , pp. 8737
    • Chan, T.H.1    Pellon, P.2
  • 38
    • 0025367226 scopus 로고
    • It is also noteworthy that the interaction of C-Si σ orbital with the nonbonding p orbital of the nitrogen raises the HOMO level which in turn enhances the susceptibility toward oxidation. (a) Yoshida, J.; Maekawa, T.; Murata, T.; Matsunaga, S.; Isoe, S. J. Am. Chem. Soc. 1990, 112, 1962.
    • (1990) J. Am. Chem. Soc. , vol.112 , pp. 1962
    • Yoshida, J.1    Maekawa, T.2    Murata, T.3    Matsunaga, S.4    Isoe, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.