메뉴 건너뛰기




Volumn 29, Issue 6, 2004, Pages 457-464

Unoprostone isopropyl rescues retinal progenitor cells from apoptosis in vitro

Author keywords

Apoptosis; Docosanoid; Neuroprotection; Retina; Unoprostone isopropyl

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; KT 5823; NEUROPROTECTIVE AGENT; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNOPROSTONE ISOPROPYL ESTER;

EID: 12344253168     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1080/02713680490889465     Document Type: Article
Times cited : (23)

References (56)
  • 1
    • 0025868618 scopus 로고
    • Effects of topical application of UF-021, a novel prostaglandin derivative, on aqueous humor dynamics in normal human eyes
    • Sakurai M, Araie M, Oshika T, et al. Effects of topical application of UF-021, a novel prostaglandin derivative, on aqueous humor dynamics in normal human eyes. Jpn J Ophthalmol. 1991;35:156-165.
    • (1991) Jpn J Ophthalmol , vol.35 , pp. 156-165
    • Sakurai, M.1    Araie, M.2    Oshika, T.3
  • 2
    • 0027732298 scopus 로고
    • Double-masked comparative study of UF-021 and timolol ophthalmic solutions in patients with primary open-angle glaucoma or ocular hypertension
    • Azuma I, Masuda K, Kitazawa Y, et al. Double-masked comparative study of UF-021 and timolol ophthalmic solutions in patients with primary open-angle glaucoma or ocular hypertension. Jpn J Ophthalmol. 1993;37:514-525.
    • (1993) Jpn J Ophthalmol , vol.37 , pp. 514-525
    • Azuma, I.1    Masuda, K.2    Kitazawa, Y.3
  • 3
    • 0029949561 scopus 로고    scopus 로고
    • Ocular hypotensive mechanism of topical isopropyl unoprostone, a novel prostaglandin metabolite-related drug, in rabbits
    • Taniguchi T, Haque MS, Sugiyama K, et al. Ocular hypotensive mechanism of topical isopropyl unoprostone, a novel prostaglandin metabolite-related drug, in rabbits. J Ocur-Pharmacol Ther. 1996;12:489-498.
    • (1996) J Ocur-Pharmacol Ther , vol.12 , pp. 489-498
    • Taniguchi, T.1    Haque, M.S.2    Sugiyama, K.3
  • 4
    • 0030992066 scopus 로고    scopus 로고
    • Clinical evaluation of UF-021 (Rescula; isopropyl unoprostone)
    • Yamamoto T, Kitazawa Y, Azuma I, et al. Clinical evaluation of UF-021 (Rescula; isopropyl unoprostone). Surv Ophthalmol. 1997;41:S99-S103.
    • (1997) Surv Ophthalmol , vol.41
    • Yamamoto, T.1    Kitazawa, Y.2    Azuma, I.3
  • 5
    • 0032029395 scopus 로고    scopus 로고
    • A comparative study of latanoprost (Xalatan) and isopropyl unoprostone (Rescula) in normal and glaucomatous monkey eyes
    • Serle JB, Podos SM, Kitazawa Y, et al. A comparative study of latanoprost (Xalatan) and isopropyl unoprostone (Rescula) in normal and glaucomatous monkey eyes. Jpn J Ophthalmol. 1998;42:95-100.
    • (1998) Jpn J Ophthalmol , vol.42 , pp. 95-100
    • Serle, J.B.1    Podos, S.M.2    Kitazawa, Y.3
  • 6
    • 0035150975 scopus 로고    scopus 로고
    • A double-masked, randomized clinical trial comparing latanoprost with unoprostone in patients with open-angle glaucoma or ocular hypertension
    • Susanna R Jr, Giampani J Jr, Borges AS, et al. A double-masked, randomized clinical trial comparing latanoprost with unoprostone in patients with open-angle glaucoma or ocular hypertension. Ophthalmology. 2001;108:259-263.
    • (2001) Ophthalmology , vol.108 , pp. 259-263
    • Susanna Jr., R.1    Giampani Jr., J.2    Borges, A.S.3
  • 7
    • 0029000279 scopus 로고
    • Effect of UF-021 on optic nerve head circulation in rabbits
    • Sugiyama T, Azuma I. Effect of UF-021 on optic nerve head circulation in rabbits. Jpn J Ophthalmol. 1995;39:124-129.
    • (1995) Jpn J Ophthalmol , vol.39 , pp. 124-129
    • Sugiyama, T.1    Azuma, I.2
  • 8
    • 0035672238 scopus 로고    scopus 로고
    • Effect of topical unoprostone on circulation of human optic nerve head and retina
    • Tamaki Y, Araie M, Tomita K, et al. Effect of topical unoprostone on circulation of human optic nerve head and retina. J Ocul Pharmacol Ther. 2001;17:517-527.
    • (2001) J Ocul Pharmacol Ther , vol.17 , pp. 517-527
    • Tamaki, Y.1    Araie, M.2    Tomita, K.3
  • 9
    • 0036183987 scopus 로고    scopus 로고
    • Long-term effect of topically applied isopropyl unoprostone on microcirculation in the human ocular fundus
    • Makimoto Y, Sugiyama T, Kojima S, et al. Long-term effect of topically applied isopropyl unoprostone on microcirculation in the human ocular fundus. Jpn J Ophthalmol. 2002;46:31-35.
    • (2002) Jpn J Ophthalmol , vol.46 , pp. 31-35
    • Makimoto, Y.1    Sugiyama, T.2    Kojima, S.3
  • 10
    • 0034924542 scopus 로고    scopus 로고
    • Photoreceptor protection against constant light-induced damage by isopropyl unoprostone, a prostaglandin F(2alpha) metabolite-related compound
    • Hayami K, Unoki K. Photoreceptor protection against constant light-induced damage by isopropyl unoprostone, a prostaglandin F(2alpha) metabolite-related compound. Ophthalmic Res. 2001;33:203-09.
    • (2001) Ophthalmic Res , vol.33 , pp. 203-209
    • Hayami, K.1    Unoki, K.2
  • 11
    • 4243752108 scopus 로고    scopus 로고
    • Retinal ganglion cell survival after transient ligation of the ophthalmic vessels and administration of unoprostone isopropyl
    • Lafuente M, Mayor-Torroglosa S, Villegas-Perez M, et al. Retinal ganglion cell survival after transient ligation of the ophthalmic vessels and administration of unoprostone isopropyl. Invest Ophthalmol Vis Sci. 2000;41:S15.
    • (2000) Invest Ophthalmol Vis Sci , vol.41
    • Lafuente, M.1    Mayor-Torroglosa, S.2    Villegas-Perez, M.3
  • 12
    • 4243720900 scopus 로고    scopus 로고
    • Neuroprotection by unoprostone, but not by latanoprost against glutamate-stimulated calcium influx and cell death in retinal ganglion cells
    • Marcheselli V, DeCoster M, Cambell Z, et al. Neuroprotection by unoprostone, but not by latanoprost against glutamate-stimulated calcium influx and cell death in retinal ganglion cells. Invest Ophthalmol Vis Sci. 2001;42:S750.
    • (2001) Invest Ophthalmol Vis Sci , vol.42
    • Marcheselli, V.1    DeCoster, M.2    Cambell, Z.3
  • 13
    • 0028043905 scopus 로고
    • Pharmacological characterization of prostaglandin-related ocular hypotensive agents
    • Goh Y, Kishino J. Pharmacological characterization of prostaglandin-related ocular hypotensive agents. Jpn J Ophthalmol. 1994;38:236-245.
    • (1994) Jpn J Ophthalmol , vol.38 , pp. 236-245
    • Goh, Y.1    Kishino, J.2
  • 14
    • 0035202802 scopus 로고    scopus 로고
    • Studies on receptor binding and signal transduction pathways of unoprostone isopropyl
    • Bhattacherjee P, Paterson CA, Percicot C. Studies on receptor binding and signal transduction pathways of unoprostone isopropyl. J Ocul Pharmacol Ther. 2001;17:433-441.
    • (2001) J Ocul Pharmacol Ther , vol.17 , pp. 433-441
    • Bhattacherjee, P.1    Paterson, C.A.2    Percicot, C.3
  • 15
    • 0037214424 scopus 로고    scopus 로고
    • Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, unoprostone, and other analogs via endogenous mouse, rat, and cloned human FP prostaglandin receptors
    • Kelly CR, Williams GW, Sharif NA. Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, unoprostone, and other analogs via endogenous mouse, rat, and cloned human FP prostaglandin receptors. J Pharmacol Exp Ther. 2003;304:238-245.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 238-245
    • Kelly, C.R.1    Williams, G.W.2    Sharif, N.A.3
  • 16
    • 0036933854 scopus 로고    scopus 로고
    • Neuroprotective properties of a synthetic docosanoid, unoprostone isopropyl: Clinical benefits in the treatment of glaucoma
    • Melamed S. Neuroprotective properties of a synthetic docosanoid, unoprostone isopropyl: clinical benefits in the treatment of glaucoma. Drugs Exp Clin Res. 2002;28:63-73.
    • (2002) Drugs Exp Clin Res , vol.28 , pp. 63-73
    • Melamed, S.1
  • 17
    • 0035650946 scopus 로고    scopus 로고
    • Mechanisms of action of unoprostone on trabecular meshwork contractility
    • Thieme H, Stumpff F, Ottlecz A, et al. Mechanisms of action of unoprostone on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2001;42:3193-3201.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 3193-3201
    • Thieme, H.1    Stumpff, F.2    Ottlecz, A.3
  • 18
    • 0026058098 scopus 로고
    • Docosahexaenoic acid (cervonic acid) incorporation into different brain regions in the awake rat
    • Sarda N, Gharib A, Moliere P, et al. Docosahexaenoic acid (cervonic acid) incorporation into different brain regions in the awake rat. Neurosci Lett. 1991;123:57-60.
    • (1991) Neurosci Lett , vol.123 , pp. 57-60
    • Sarda, N.1    Gharib, A.2    Moliere, P.3
  • 19
    • 0028243858 scopus 로고
    • Lipoxygenation of docosahexaenoic acid by the rat pineal body
    • Sawazaki S, Salem N Jr, Kim HY. Lipoxygenation of docosahexaenoic acid by the rat pineal body. J Neurochem. 1994;62:2437-2447.
    • (1994) J Neurochem , vol.62 , pp. 2437-2447
    • Sawazaki, S.1    Salem Jr., N.2    Kim, H.Y.3
  • 20
    • 0020655183 scopus 로고
    • Chemistry and metabolism of lipids in the vertebrate retina
    • Fliesler SJ, Anderson RE. Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res. 1983;22:79-131.
    • (1983) Prog Lipid Res , vol.22 , pp. 79-131
    • Fliesler, S.J.1    Anderson, R.E.2
  • 21
    • 0000066943 scopus 로고
    • Retina
    • Lajtha A, ed. New York: Plenum Press
    • Bazan NG, Reddy TS. Retina. In : Lajtha A, ed. Handbook of Neurochemistry, Vol. 8. New York: Plenum Press; 1985:209-217.
    • (1985) Handbook of Neurochemistry , vol.8 , pp. 209-217
    • Bazan, N.G.1    Reddy, T.S.2
  • 22
    • 0034634590 scopus 로고    scopus 로고
    • Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect
    • Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem. 2000;275:35215-35223.
    • (2000) J Biol Chem , vol.275 , pp. 35215-35223
    • Kim, H.Y.1    Akbar, M.2    Lau, A.3
  • 23
    • 0037407743 scopus 로고    scopus 로고
    • Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors
    • Rotstein NP, Politi LE, German OL, et al. Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors. Invest Ophthalmol Vis Sci.2003;44:2252-2259.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2252-2259
    • Rotstein, N.P.1    Politi, L.E.2    German, O.L.3
  • 24
    • 0032882209 scopus 로고    scopus 로고
    • Metabolites of isopropyl unoprostone as potential ophthalmic solutions to reduce intraocular pressure in pigmented rabbits
    • Kashiwagi K, Iizuka Y, Tsukahara S. Metabolites of isopropyl unoprostone as potential ophthalmic solutions to reduce intraocular pressure in pigmented rabbits. Jpn J Pharmacol. 1999;81:56-62.
    • (1999) Jpn J Pharmacol , vol.81 , pp. 56-62
    • Kashiwagi, K.1    Iizuka, Y.2    Tsukahara, S.3
  • 25
    • 0034876620 scopus 로고    scopus 로고
    • Isopropyl unoprostone increases the activities of matrix metalloproteinase in cultured monkey ciliary muscle cells
    • Kashiwagi K, Jin M, Suzuki M, et al. Isopropyl unoprostone increases the activities of matrix metalloproteinase in cultured monkey ciliary muscle cells. J Glaucoma. 2001;10:271-276.
    • (2001) J Glaucoma , vol.10 , pp. 271-276
    • Kashiwagi, K.1    Jin, M.2    Suzuki, M.3
  • 26
    • 0035017043 scopus 로고    scopus 로고
    • Effects of isopropyl unoprostone on melanogenesis in mouse epidermal melanocytes
    • Kashiwagi K, Tsukamoto K, Wakamatsu K, et al. Effects of isopropyl unoprostone on melanogenesis in mouse epidermal melanocytes. Jpn J Ophthalmol. 2001;45:259-263.
    • (2001) Jpn J Ophthalmol , vol.45 , pp. 259-263
    • Kashiwagi, K.1    Tsukamoto, K.2    Wakamatsu, K.3
  • 27
    • 0029867463 scopus 로고    scopus 로고
    • Establishment of an E1A-immortalized retinal cell culture
    • Seigel GM. Establishment of an E1A-immortalized retinal cell culture. In Vitro Cell Dev Biol Anim. 1996;32:66-68.
    • (1996) In Vitro Cell Dev Biol Anim , vol.32 , pp. 66-68
    • Seigel, G.M.1
  • 28
    • 0034657707 scopus 로고    scopus 로고
    • The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells
    • Tezel G, Wax MB. The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. J Neurosci. 2000;20:3552-3562.
    • (2000) J Neurosci , vol.20 , pp. 3552-3562
    • Tezel, G.1    Wax, M.B.2
  • 29
    • 0035980149 scopus 로고    scopus 로고
    • Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3
    • Barber AJ, Nakamura M, Wolpert EB, et al. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. J Biol Chem. 2001;276:32814-32821.
    • (2001) J Biol Chem , vol.276 , pp. 32814-32821
    • Barber, A.J.1    Nakamura, M.2    Wolpert, E.B.3
  • 30
    • 0035941260 scopus 로고    scopus 로고
    • Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons
    • Nakamura M, Barber AJ, Antonetti DA, et al. Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons. J Biol Chem. 2001;276:43748-43755.
    • (2001) J Biol Chem , vol.276 , pp. 43748-43755
    • Nakamura, M.1    Barber, A.J.2    Antonetti, D.A.3
  • 32
    • 0032724840 scopus 로고    scopus 로고
    • Density-dependent resisitance to apoptosis in retinal cells
    • Tezel GM, Seigel GM, Wax MB. Density-dependent resisitance to apoptosis in retinal cells. Curr Eye Res. 1999;19:377-388.
    • (1999) Curr Eye Res , vol.19 , pp. 377-388
    • Tezel, G.M.1    Seigel, G.M.2    Wax, M.B.3
  • 33
    • 0033213838 scopus 로고    scopus 로고
    • 1-Deprenyl blocking apoptosis and regulating gene expression in cultured retinal neurons
    • Xu L, Ma J, Seigel GM, et al. 1-Deprenyl blocking apoptosis and regulating gene expression in cultured retinal neurons. Biochem Pharmacol. 1999;58:1183-1190.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1183-1190
    • Xu, L.1    Ma, J.2    Seigel, G.M.3
  • 34
    • 0032878142 scopus 로고    scopus 로고
    • Inhibiton of caspase activity in retinal cell apoptosis induced by various stimuli in vitro
    • Tezel G, Wax MB. Inhibiton of caspase activity in retinal cell apoptosis induced by various stimuli in vitro. Invest Ophthalmol Vis Sci. 1999;40:2660-2667.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2660-2667
    • Tezel, G.1    Wax, M.B.2
  • 35
    • 0037147619 scopus 로고    scopus 로고
    • Retinal precursor cells express functional ionotropic glutamate and GABA receptors
    • Sun W, Seigel GM, Salvi RJ. Retinal precursor cells express functional ionotropic glutamate and GABA receptors. Neuroreport. 2002;13:2421-2424.
    • (2002) Neuroreport , vol.13 , pp. 2421-2424
    • Sun, W.1    Seigel, G.M.2    Salvi, R.J.3
  • 36
    • 0036956469 scopus 로고    scopus 로고
    • Alteration of the intracellular pH and apoptosis induction in a retinal cell line by the AGE-inducing agent glyoxal
    • Reber F, Kasper M, Siegner A, et al. Alteration of the intracellular pH and apoptosis induction in a retinal cell line by the AGE-inducing agent glyoxal. Graefe's Arch Clin Exp Ophthalmol. 2002;240:1022-1032.
    • (2002) Graefe's Arch Clin Exp Ophthalmol , vol.240 , pp. 1022-1032
    • Reber, F.1    Kasper, M.2    Siegner, A.3
  • 37
    • 0034533133 scopus 로고    scopus 로고
    • Transduction of survival signals in neuronstake your PIK?
    • Allsopp TE. Transduction of survival signals in neuronstake your PIK? Trends Neurosci. 2000;23:593.
    • (2000) Trends Neurosci , vol.23 , pp. 593
    • Allsopp, T.E.1
  • 38
    • 0035986856 scopus 로고    scopus 로고
    • Functions of PI3-kinase in development of the nervous system
    • Rodgers EE, Theibert AB. Functions of PI3-kinase in development of the nervous system. Int J Dev Neurosci. 2002;20:187-197.
    • (2002) Int J Dev Neurosci , vol.20 , pp. 187-197
    • Rodgers, E.E.1    Theibert, A.B.2
  • 39
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 1997;91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 40
    • 0032515027 scopus 로고    scopus 로고
    • Regulation of cell death protease caspase-9 by phosphorylation
    • Cardone MH, Roy N, Stennicke HR, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science. 1998;282:1318-1321.
    • (1998) Science , vol.282 , pp. 1318-1321
    • Cardone, M.H.1    Roy, N.2    Stennicke, H.R.3
  • 41
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999;96:857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 42
    • 0035133227 scopus 로고    scopus 로고
    • Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    • Kim AH, Khursigara G, Sun X, et al. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol. 2001;21:893-901.
    • (2001) Mol Cell Biol , vol.21 , pp. 893-901
    • Kim, A.H.1    Khursigara, G.2    Sun, X.3
  • 43
    • 0036634250 scopus 로고    scopus 로고
    • Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells
    • Fiscus RR. Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells. Neurosignals. 2002;11:175-190.
    • (2002) Neurosignals , vol.11 , pp. 175-190
    • Fiscus, R.R.1
  • 44
    • 0031772217 scopus 로고    scopus 로고
    • Nitric oxide as a retrograde messenger during long-term potentiation in hippocampus
    • Hawkins RD, Son H, Arancio O. Nitric oxide as a retrograde messenger during long-term potentiation in hippocampus. Prog Brain Res. 1998;118:155-172.
    • (1998) Prog Brain Res , vol.118 , pp. 155-172
    • Hawkins, R.D.1    Son, H.2    Arancio, O.3
  • 45
    • 0023158501 scopus 로고
    • Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures
    • Fiscus RR, Robles BT, Waldman SA, et al. Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures. J Neurochem. 1987;48:522-528.
    • (1987) J Neurochem , vol.48 , pp. 522-528
    • Fiscus, R.R.1    Robles, B.T.2    Waldman, S.A.3
  • 46
    • 0039533148 scopus 로고    scopus 로고
    • Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor
    • Estevez AG, Spear N, Thompson JA, et al. Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor. J Neurosci. 1998;18:3708-3714.
    • (1998) J Neurosci , vol.18 , pp. 3708-3714
    • Estevez, A.G.1    Spear, N.2    Thompson, J.A.3
  • 47
    • 0035930505 scopus 로고    scopus 로고
    • Anti-apoptotic effect of cGMP in cultured astrocytes: Inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore
    • Takuma K, Phuagphong P, Lee E, et al. Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore. J Biol Chem. 2001;276:48093-48099.
    • (2001) J Biol Chem , vol.276 , pp. 48093-48099
    • Takuma, K.1    Phuagphong, P.2    Lee, E.3
  • 48
    • 0033566627 scopus 로고    scopus 로고
    • Nitric oxide protects PC 12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling
    • Kim YM, Chung HT, Kim SS, et al. Nitric oxide protects PC 12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling. J Neurosci. 1999;19:6740-6747.
    • (1999) J Neurosci , vol.19 , pp. 6740-6747
    • Kim, Y.M.1    Chung, H.T.2    Kim, S.S.3
  • 49
    • 0035081572 scopus 로고    scopus 로고
    • Maxi-K potassium channels: Form, function, and modulation of a class of endogenous regulators of intracellular calcium
    • Gribkoff VK, Starrett JE Jr, Dworetzky SI. Maxi-K potassium channels: form, function, and modulation of a class of endogenous regulators of intracellular calcium. Neuroscientist. 2001;7:166-177.
    • (2001) Neuroscientist , vol.7 , pp. 166-177
    • Gribkoff, V.K.1    Starrett Jr., J.E.2    Dworetzky, S.I.3
  • 50
    • 0034776936 scopus 로고    scopus 로고
    • Latanoprost exerts neuroprotective activity in vitro and in vivo
    • Drago F, Valzelli S, Emmi I, et al. Latanoprost exerts neuroprotective activity in vitro and in vivo. Exp Eye Res. 2001;72:479-486.
    • (2001) Exp Eye Res , vol.72 , pp. 479-486
    • Drago, F.1    Valzelli, S.2    Emmi, I.3
  • 51
    • 0035094829 scopus 로고    scopus 로고
    • Neuroprotective effect and intraocular penetration of nipradilol, a beta-blocker with nitric oxide donative action
    • Mizuno K, Koide T, Yoshimura M, et al. Neuroprotective effect and intraocular penetration of nipradilol, a beta-blocker with nitric oxide donative action. Invest Ophthalmol Vis Sci. 2001;42:688-694.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 688-694
    • Mizuno, K.1    Koide, T.2    Yoshimura, M.3
  • 52
    • 0037064268 scopus 로고    scopus 로고
    • Nipradilol inhibits apoptosis by preventing the activation of caspase-3 via S-nitrosylation and the cGMP-dependent pathway
    • Tomita H, Nakazawa T, Sugano E, et al. Nipradilol inhibits apoptosis by preventing the activation of caspase-3 via S-nitrosylation and the cGMP-dependent pathway. Eur J Pharmacol. 2002;452:263-268.
    • (2002) Eur J Pharmacol , vol.452 , pp. 263-268
    • Tomita, H.1    Nakazawa, T.2    Sugano, E.3
  • 53
    • 0037146913 scopus 로고    scopus 로고
    • Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retina
    • Goto W, Ota T, Morikawa N, et al. Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retina. Brain Res. 2002;958:10-19.
    • (2002) Brain Res , vol.958 , pp. 10-19
    • Goto, W.1    Ota, T.2    Morikawa, N.3
  • 54
    • 0037375287 scopus 로고    scopus 로고
    • The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: Comparison with betaxolol
    • Wood JP, Schmidt KG, Melena J, et al. The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: comparison with betaxolol. Exp Eye Res. 2003;76:505-516.
    • (2003) Exp Eye Res , vol.76 , pp. 505-516
    • Wood, J.P.1    Schmidt, K.G.2    Melena, J.3
  • 55
    • 0036015940 scopus 로고    scopus 로고
    • Transscleral drug delivery to the retina and choroid
    • Ambati J, Adamis AP. Transscleral drug delivery to the retina and choroid. Prog Retin Eye Res. 2002;21:145-151.
    • (2002) Prog Retin Eye Res , vol.21 , pp. 145-151
    • Ambati, J.1    Adamis, A.P.2
  • 56
    • 0038031618 scopus 로고    scopus 로고
    • Differential effects of aging on transport properties of anterior and posterior human sciera
    • Boubriak OA, Urban JP, Bron AJ. Differential effects of aging on transport properties of anterior and posterior human sciera. Exp Eye Res. 2003;76:701-713.
    • (2003) Exp Eye Res , vol.76 , pp. 701-713
    • Boubriak, O.A.1    Urban, J.P.2    Bron, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.