FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres

Journal of Controlled Release

Volumn 58, Issue 3, 1999, Pages 357-366

  Fu, Karen ^a   Griebenow, Kai ^b   Hsieh, Lisa ^c   Klibanov, Alexander M ^d   Langer, Robert ^a,c  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

FTIR spectroscopy; Microsphere; Poly(lactic co glycolic acid); Protein stability; Trehalose

Indexed keywords

BOVINE SERUM ALBUMIN; LYSOZYME; MICROSPHERE; POLYGLACTIN; RG 503; UNCLASSIFIED DRUG;

ARTICLE; ENCAPSULATION; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN SECRETION; TECHNIQUE;

ANIMALS; CATTLE; CHICKENS; DRUG STABILITY; EGG WHITE; EXCIPIENTS; LACTIC ACID; MICROSPHERES; MURAMIDASE; POLYGLYCOLIC ACID; POLYMERS; PROTEIN STRUCTURE, SECONDARY; SERUM ALBUMIN, BOVINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TREHALOSE;

EID: 0033003073     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00192-8     Document Type: Article

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