B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-β in Primary Human Cardiac Fibroblasts: Fibrosis, Myofibroblast Conversion, Proliferation, and Inflammation

Circulation Research

Volumn 94, Issue 4, 2004, Pages 453-461

  Kapoun, Ann M ^a   Liang, Faquan ^a   O'Young, Gilbert ^a   Damm, Deborah L ^a   Quon, Diana ^a   White, R Tyler ^a   Munson, Kimberly ^a   Lam, Andrew ^a   Schreiner, George F ^a   Protter, Andrew A ^a  

^a SCIOS INC   (United States)

Author keywords

B type natriuretic peptide; Cardiac fibroblasts; Fibrosis; Transforming growth factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BRAIN NATRIURETIC PEPTIDE; COLLAGEN TYPE 1; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ALPHA SMOOTH MUSCLE ACTIN 2 GENE; ARTICLE; CASE REPORT; CELL PROLIFERATION; CELL TRANSFORMATION; COLLAGEN 1 GENE; CONTROLLED STUDY; COX2 GENE; CTGF GENE; DNA MICROARRAY; FGF18 GENE; FIBONECTIN GENE; FIBROBLAST; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HUMAN; HUMAN CELL; IGF1 GENE; IGFBP10 GENE; IL6 GENE; INFLAMMATION; MALE; MEMBER 4 GENE; MYOFIBROBLAST; NONMUSCLE MYOSIN HEAVY CHAIN GENE; PAI 1 GENE; PDGFA GENE; PRIORITY JOURNAL; RNA PROCESSING; RNA PROFILE; SIGNAL TRANSDUCTION; TIMP3 GENE; TNF ALPHA INDUCED PROTEIN 6 GENE; TNF SUPERFAMILY GENE; WESTERN BLOTTING;

ADOLESCENT; BLOTTING, WESTERN; BUTADIENES; CELL DIVISION; CELLS, CULTURED; CYCLIC GMP; ENZYME INHIBITORS; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBROSIS; FLAVONOIDS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MUSCLE PROTEINS; NATRIURETIC PEPTIDE, BRAIN; NITRILES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA; VENTRICULAR REMODELING;

EID: 12144290445     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000117070.86556.9F     Document Type: Article

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