Identification of an Inhibitor Targeting Macrophage Production of Monocyte Chemoattractant Protein-1 as TGF-β11

Journal of Immunology

Volumn 159, Issue 3, 1997, Pages 1404-1411

  Kitamura, Masanori ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CULTURE MEDIUM; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FISCHER 344 RAT; GLOMERULONEPHRITIS; GLOMERULUS; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MESANGIUM; METABOLISM; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELL LINE; CHEMOKINE CCL2; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; GLOMERULAR MESANGIUM; GLOMERULONEPHRITIS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY GLOMERULUS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR AP-1; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031204379     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Miller, M. D., and M. S. Krangel. 1992. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit. Rev. Immunol. 12:17.
2. Leonard, E. J., and T. Yoshimura. 1990. Human monocyte chemoattractant protein-1 (MCP-1). Immunol. Today 11:97.
3. Yoshinura, T., E. A. Robinson, S. Tanaka, E. Appella, and E. J. Leonard. 1989. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J. Immunol. 142:1956.
4. Matsushima, K., C. G. Larsen, G. C. DuBois, and J. J. Oppenheim. 1989. Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. J. Exp. Med. 169: 1485.
5. Yla-Herttuala, S., B. A. Lipton, M. E. Rosenfeld, T. Sarkioja, T. Yoshimura, E. J. Leonard, J. L. Witztum, and D. Steinberg. 1991. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. USA 88:5252.
6. Rollins, B. J., and J. S. Pobert. 1991. Interleukin-4 induces the synthesis and secretion of MCP-1/JE by human endothelial cells. Am. J. Pathol. 138:1315.
7. Kikuchi, H., S. Hanazawa, A. Takeshita, Y. Nakada, Y. Yamashita, and S. Kitano. 1994. Interleukin-4 acts as a potent stimulator for expression of monocyte chemoattractant JE/MCP-1 in mouse peritoneal macrophages. Biochem. Biophys. Res. Commun. 203:562.
8. Zhu, J. F., A. J. Valente, J. A. Lorenzo, D. Carnes, and D. T. Graves. 1994. Expression of monocyte chemoattractant protein 1 in human osteoblastic cells stimulated by proinflammatory mediators. J. Bone Miner. Res. 9:1123.
9. Sironi, M., C. Munoz, T. Pollicino, A. Siboni, F. L. Sciacca, S. Bernasconi, A. Vecchi, F. Colotta, and A. Mantovani. 1993. Divergent effects of interleukin-10 on cytokine production by mononuclear phagocytes and endothelial cells. Eur. J. Immunol. 23:2692.
10. Seitz, M., P. Loetscher, B. Dewald, H. Towbin, H. Gallati, and M. Baggiolini. 1995. Interleukin-10 differentially regulates cytokine inhibitor and chemokine release from blood mononuclear cells and fibroblasts. Eur. J. Immunol. 25:1129.
11. Seitz, M., P. Loetscher, B. Dewald, H. Towbin, M. Ceska, and M. Baggiolini. 1994. Production of interleukin-1 receptor antagonist, inflammatory chemotactic proteins, and prostaglandin E by rheumatoid and osteoarthritic synoviocytes: regulation by IFN-γ and IL-4. J. Immunol. 152:2060.
12. Hurwitz, A. A., W. D. Lyman, and J. W. Berman. 1995. Tumor necrosis factor-α and transforming growth factor-β up-regulate astrocyte expression of monocyte chemoattractant protein-1. J. Neuroimmunol. 57:193.
13. Takeshita, A., Y. Chen, A. Watanabe, S. Kitano, and S. Hanazawa. 1995. TGF-β induces expression of monocyte chemoattractant JE/monocyte chemoattractant protein 1 via transcriptional factor AP-1 induced by protein kinase in osteoblastic cells. J. Immunol. 155:419.
14. 1 and IL-4. Exp. Hematol. 23:482.
15. Antoniades, H. N., J. Neville-Golden, T. Galanopoulos, R. L. Kradin, A. J. Valente, and D. T. Graves. 1992. Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis. Proc. Natl. Acad. Sci. USA 89:5371.
16. Villiger, P. M., R. Terkeltaub, and M. Lotz. 1992. Production of monocyte chemoattractant protein-1 by inflamed synovial tissue and cultured synoviocytes. J. Immunol. 149:722.
17. Stahl, R. A. K., F. Thaiss, M. Disser, U. Helmchen, K. Hora, and D. Schlondorff. 1993. Increased expression of monocyte chemoattractant protein-1 in antithymocyte antibody-induced glomerulonephritis. Kidney Int. 44:1036.
18. Kitamura, M., T. Mitarai, N. Maruyama, R. Nagasawa, H. Yoshida, and O. Sakai. 1991 Mesangial cell behavior in a three-dimensional extracellular matrix. Kidney Int. 40:653.
19. 1 suppresses mitogenesis and IL-1 response in the glomerulus. Kidney Int. 48:1747.
20. Hortelano, S., A. M. Genaro, and L. Bosca. 1993. Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages. FEBS Lett. 20:135.
21. Kawachi, H., M. Orisaka, K. Matsui, T. Iwanaga, S. Toyabe, T. Oite, and F. Shimizu. 1992. Epitope-specific induction of mesangial lesions with proteinuria by a MoAb against mesangial cell surface antigen. Clin. Exp. Immunol. 88:399.
22. Yokoo, T., and M. Kitamura. 1996. Dual regulation of IL-1β-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-κB and AP-1. Am. J. Physiol. 270:F123.
23. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal. Biochem. 162: 156.
24. Kitamura, M., T. Shirasawa, T. Mitarai, T. Muramatsu, and N. Maruyama. 1993. A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines. Am. J. Pathol. 142:425.
25. Rollins, B. J., E. D. Morrison, and C. D. Stiles. 1988. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc. Natl. Acad. Sci. USA 85:3738.
26. 1 (Ser223, 225). EMBO J. 11:1599.
27. McDonnell, S. E., L. D. Kerr, and L. M. Matrisian. 1990. Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C. Mol. Cell. Biol. 10:4284.
28. 1 is the predominant paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells. J. Immunol. 156:2964.
29. Cone, J. L., D. R. Brown, and J. E. DeLarco. 1988. Improved method of purification of transforming growth factor, type β from platelets. Anal. Biochem. 168:71.
30. 1 reduces macrophage adhesiveness with consequent deactivation. Kidney Int. 50:445.
31. Introna, M., R. C. Bast, C. S. Tannenbaum, T. A. Hamilton, and D. O. Adams. 1987. The effect of LPS on expression of the early "competence" genes JE and KC in murine peritoneal macrophages. J. Immunol. 138:3891.
32. Kitamura, M., T. Mitarai, R. Nagasawa, and N. Maruyama. 1996. Differentiated phenotype of glomerular mesangial cells in nodular culture. Am. J. Physiol. 270: F614.
33. Toyabe, S., and T. Iwanaga. 1992. An ultrastructural study of proliferative nephritis induced experimentally by a monoclonal antibody against mesangial cells. Virchows Arch. B Cell Pathol. 61:397.
34. Brown, P. D., L. M. Wakefield, A. D. Levinson, and M. B. Sporn. 1990. Physicochemical activation of recombinant latent transforming growth factor-beta's 1, 2, 3. Growth Factors 3:35.
35. Kaname, S., S. Uchida, E. Ogata, and K. Kurokawa. 1992. Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells. Kidney Int. 42:1319.
36. Shyy, J. Y. J., M. C. Lin, J. Han, Y. Lu, M Petrime, and S. Chien. 1995. The cis-acting phorbol ester "12-o-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc. Natl. Acad. Sci. USA 92:8069.
37. Yoshimura, T., and E. J. Leonard. 1990. Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE. J. Immunol. 144:2377.
38. Takehara, K., E. C. LeRoy, and G. R. Grotendorst. 1987. TGF-β inhibition of endothelial cell proliferation: alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression. Cell 49:415.
39. Kawahara, R. S., Z-W. Deng, and T. F. Deuel. 1991. Glucocorticoids inhibit the transcriptional induction of JE, a platelet-derived growth factor-inducible gene. J. Biol. Chem. 266:13261.
40. Rolfe, M. W., S. L. Kunkel, T. J. Standiford, M. B. Orringer, S. H. Phan, H. L. Evanoff, M. D. Burdick, and R. M. Strieter. 1992. Expression and regulation of human pulmonary fibroblast-derived monocyte chemotactic peptide-1. Am. J. Physiol. 263:L536.
41. Martin, C. A., and H. E. Dorf. 1991. Differential regulation of interleukin-6, macrophage inflammatory protein-1, and JE/MCP-1 cytokine expression in macrophage cell lines. Cell. Immunol. 135:245.
42. Hanazawa, S., A. Takeshita, and S. Kitano. 1994. Retinoic acid suppression of c-fos gene inhibits expression of tumor necrosis factor-α-induced monocyte chemoattractant JE/MCP-1 in clonal osteoblastic MC3T3-E1 cells. J. Biol. Chem. 269:21379.
43. Massague, J. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6:597.
44. Ueda, A., K. Okuda, S. Ohno, A. Shirai, T. Igarashi, K. Matsunaga, J. Fukushima. S. Kawamoto, Y. Ishigatsubo, and T. Okubo. 1994. NF-κB and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J. Immunol. 153:2052.
45. Rollins, B. J., P. Stier, T. Ernst, and G. G. Wong. 1989. The human homolog of the JE gene encodes a monocyte secretory protein. Mol. Cell. Biol. 9:4687.
46. Shyy, Y.-J., Y.-S. Li, and P. E. Kolattukudy. 1990. Structure of human monocyte chemotactic protein gene and its regulation by TPA. Biochem. Biophys. Res. Commun. 169:346.
47. Shyy, Y. J., Y. S. Li, and P. E. Kolattukudy. 1993. Activation of MCP-1 gene expression is mediated through multiple signalling pathways. Biochem. Biophys. Res. Commun. 192:693.
48. Rovin, B. H., and L. C. Tan. 1994. Role of protein kinase pathways in IL-1-induced chemoattractant expression by human mesangial cells. Kidney Int. 46: 1059.
49. Kawahara, R. S., Z. W. Deng, D. J Denkinger, and T. F. Deuel. 1994. Role of serine/threonine kinases in the induction of JE, a platelet-derived growth factor inducible gene. Biochem. Biophys. Res. Commun. 203:1815.
50. Hambleton, J., S. L. Weinstein, L. Lem, and A. L. DeFranco. 1996. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA 93:2774.
51. Main, I. W., D. J. Nikolic-Paterson, and R. C. Atkins. 1992. T cells and macrophages and their role in renal injury. Semin. Nephrol. 12:395.
52. Rovin, B. H., M. Rumancik, L. Tan, and J. Dickerson. 1994. Glomerular expression of monocyte chemoattractant protein-1 in experimental and human glomerulonephritis. Lab. Invest. 71:536.
53. Neugarten, J., G. W. Feith, K. J. M. Assmann, Z. Shan, E. R. Stanley, and D. Schlondorff. 1995. Role of macrophages and colony-stimulating factor-1 in murine antiglomerulur basement membrane glomerulonephritis. J. Am. Soc. Nephrol. 5:1903.
54. Kawachi, H., T. Iwanaga, S. Toyabe, T. Oite, and F. Shimizu. 1992. Mesangial sclerotic change with persistent proteinuria in rats after two consecutive injections of monoclonal antibody 1-22-3. Clin. Exp. Immunol. 90:129.
55. Okuda, S., L. R. Languino, E. Ruoslahti, and W. A. Border. 1990. Elevated expression of transforming growth factor-β and proteoglycan production in experimental glomerulonephritis: possible role in expansion of the mesangial extracellular matrix. J. Clin. Invest. 86:453.
56. 1 underlies development of progressive kidney fibrosis. Kidney Int. 45:916.
57. Kitamura, M., and T. S. Sütö. 1997. TGF-β and glomerulonephritis: antiinflammatory versus prosclerotic actions. Nephrol. Dial. Transplant. 12:669.
58. Largen, P. J., F. W. K. Tam, A. J. Rees, and V. Cattell. 1995. Rat mesangial cells have a selective role in macrophage recruitment and activation. Exp. Nephrol. 3:34.
59. Sütö, T. S., L. G. Fine, F. Shimizu, and M. Kitamura. 1997. In vivo transfer of engineered macrophages into the glomerulus: endogenous TGF-β-mediated "defense" against macrophage-induced glomerular cell activation. J. Immunol. In press.