In vivo kinetics of Cajal body components

Journal of Cell Biology

Volumn 164, Issue 6, 2004, Pages 831-842

  Dundr, Miroslav ^a   Hebert, Michael D ^c,d   Karpova, Tatiana S ^b   Stanek, David ^e   Xu, Hongzi ^c   Shpargel, Karl B ^d   Meier, U Thomas ^f   Neugebauer, Karla M ^e   Matera, A Gregory ^d   Misteli, Tom ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cajal body; Coilin; Gems; iFRAP; SMN

Indexed keywords

RIBOSOME RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEOLAR RIBONUCLEOPROTEIN;

ARTICLE; CELL SURVIVAL; CELL TYPE; COILED BODY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELA CELL; HUMAN; HUMAN CELL; KINETICS; PLASMID; PRIORITY JOURNAL;

ANIMALS; CELL NUCLEOLUS; COILED BODIES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELA CELLS; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA SPLICING; RNA-BINDING PROTEINS; SPLICEOSOMES; TIME FACTORS;

EID: 12144290254     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200311121     Document Type: Article

References (59)

1. Bell, M., S. Schreiner, A. Damianov, R. Reddy, and A. Bindereif. 2002. p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor. EMBO J. 21:2724-2735.
2. Boisvert, F.M., M.J. Kruhlak, A.K. Box, M.J. Hendzel, and D.P. Bazett-Jones. 2001. The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body. J. Cell Biol. 152:1099-1106.
3. Boisvert, F.M., J. Cote, M.C. Boulanger, P. Cleroux, F. Bachand, C. Autexier, and S. Richard. 2002. Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing. J. Cell Biol. 159:957-969.
4. Boudonck, K., L. Dolan, and P.J. Shaw. 1999. The movement of coiled bodies visualized in living plant cells by the green fluorescent protein. Mol. Biol. Cell. 10:2297-2307.
5. Catmo-Fonseca, M. 2002. New clues to the function of the Cajal body. EMBO Rep. 3:726-727.
6. Carvalho, T., F. Almeida, A. Calapez, M. Lafarga, M.T. Berciano, and M. Carmo-Fonseca. 1999. The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body. J. Cell Biol. 147:715-728.
7. Chen, D., and S. Huang. 2001. Nucleolar components involved in ribosome biogenesis cycle between the nucleolus and nucleoplasm in interphase cells. J. Cell Biol. 153:169-176.
8. Darzacq, X., B.E. Jady, C. Verheggen, A.M. Kiss, E. Bertrand, and T. Kiss. 2002. Cajal body-specific small nuclear RNAs: a novel class of 2′-O-methylation and pseudouridylation guide RNAs. EMBO J. 21:2746-2756.
9. Dundr, M., T. Misteli, and M.O. Olson. 2000. The dynamics of postmitotic reassembly of the nucleolus. J. Cell Biol. 150:433-446.
10. Dundr, M., U. Hoffmann-Rohrer, Q. Hu, I. Grummt, L.I. Rothblum, R.D. Phair, and T. Misteli. 2002. A kinetic framework for a mammalian RNA polymerase in vivo. Science. 298:1623-1626.
11. Fischer, U., Q. Liu, and G. Dreyfuss. 1997. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. Cell. 90:1023-1029.
12. Friesen, W.J., and G. Dreyfuss. 2000. Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). J. Biol. Chem. 275:26370-26375.
13. Gall, J.G. 2000. Cajal bodies: the first 100 years. Annu. Rev. Cell Dev. Biol. 16: 273-300.
14. Handwerger, K.E., C. Murphy, and J.G. Gall. 2003. Steady-state dynamics of Cajal body components in the Xenopus germinal vesicle. J. Cell Biol. 160:495-504.
15. Hebert, M.D., and A.G. Matera. 2000. Self-association of coilin reveals a common theme in nuclear body localization. Mol. Biol. Cell. 11:4159-4171.
16. Hebert, M.D., P.W. Szymczyk, K.B. Shpargel, and A.G. Matera. 2001. Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein. Genes Dev. 15:2720-2729.
17. Hebert, M.D., K.B. Shpargel, J.K. Ospina, K.E. Tucker, and A.G. Matera. 2002. Coilin methylation regulates nuclear body formation. Dev. Cell. 3:329-337.
18. Isaac, C., Y. Yang, and U.T. Meier. 1998. Nopp140 functions as a molecular link between the nucleolus and the coiled bodies. J. Cell Biol. 142:319-329.
19. Jady, B.E., X. Darzacq, K.E. Tucker, A.G. Matera, E. Bertrand, and T. Kiss. 2003. Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm. EMBO J. 22:1878-1888.
20. Jones, K.W., K. Gorzynski, C.M. Hales, U. Fischer, F. Badbanchi, R.M. Terns, and M.P. Terns. 2001. Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin. J. Biol. Chem. 276:38645-38651.
21. Karpova, T.S., C.T. Baumann, L. He, X. Wu, A. Grammer, P. Lipsky, G.L. Hager, and J.G. McNally. 2003. Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser. J. Microsc. 209:56-70.
22. Lazdins, I.B., M. Delannoy, and B. Sollner-Webb. 1997. Analysis of nucleolar transcription and processing domains and pre-rRNA movements by in situ hybridization. Chromosoma. 105:481-495.
23. Lefebvre, S., P. Burlet, L. Viollet, S. Bertrandy, C. Huber, C. Belser, and A. Munnich. 2002. A novel association of the SMN protein with two major non-ribosomal nucleolar proteins and its implication in spinal muscular atrophy. Hum. Mol. Genet. 11:1017-1027.
24. Leung, A.K., and A.I. Lamond. 2002. In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles. J. Cell Biol. 157:615-629.
25. Lorson, C.L., J. Strasswimmer, J.M. Yao, J.D. Baleja, E. Hahnen, B. Wirth, T. Le, A.H. Burghes, and E.J. Androphy. 1998. SMN oligomerization defect correlates with spinal muscular atrophy severity. Nat. Genet. 19:63-66.
26. Liu, Q., and G. Dreyfuss. 1996. A novel nuclear structure containing the survival of motor neurons protein. EMBO J. 15:3555-3565.
27. Liu, J., M.D. Hebert, Y. Ye, D.J. Templeton, H. Kung, and A.G. Matera. 2000. Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies. J. Cell. Sci. 113:1543-1552.
28. Matera, A.G. 1999. Nuclear bodies: multifaceted subdomains of the interchromatin space. Trends Cell Biol. 9:302-309.
29. Matera, A.G., and M.R. Frey. 1998. Coiled bodies and gems: Janus or gemini? Am. J. Hum. Genet. 63:317-321.
30. Meister, G., C. Eggert, and U. Fischer. 2002. SMN-mediated assembly of RNPs: a complex story. Trends Cell Biol. 12:472-478.
31. Mouaikel, J., U. Narayanan, C. Verheggen, A.G. Matera, E. Bertrand, J. Tazi, and R. Bordonne. 2003. Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron. EMBO Rep. 4:616-622.
32. Narayanan, U., J.K. Ospina, M.R. Frey, M.D. Hebert, and A.G. Matera. 2002. SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. Hum. Mol. Genet. 11:1785-1795.
33. Ochs, R.L., T.W.J. Stein, and E.M. Tan. 1994. Coiled bodies in the nucleolus of breast cancer cells. J. Cell Sci. 107:385-399.
34. Ogg, S.C., and A.I. Lamond. 2002. Cajal bodies and coilin-moving towards function. J. Cell Biol. 159:17-21.
35. Ou, Q., J.F. Mouillet, X. Yan, C. Dorn, P.A. Crawford, and Y. Sadovsky. 2001. The DEAD box protein DP103 is a regulator of steroidogenic factor-1. Mol. Endocrinol. 15:69-79.
36. Paushkin, S., A.K. Gubitz, S. Massenet, and G. Dreyfuss. 2002. The SMN complex, an assemblyosome of ribonucleoproteins. Curr. Opin. Cell Biol. 14: 305-312.
37. Pellizzoni, L., J. Baccon, B. Charroux, and G. Dreyfuss. 2001. The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1. Curr. Biol. 11:1079-1088.
38. Phair, R.D., and T. Misteli. 2000. High mobility of proteins in the mammalian cell nucleus. Nature. 404:604-609.
39. Phair, R.D., S.A. Gorski, and T. Misteli. 2004. Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol. 375:393-414.
40. Platani, M., I. Goldberg, J.R. Swedlow, and A.I. Lamond. 2000. In vivo analysis of Cajal body movement, separation, and joining in live human cells. J. Cell Biol. 151:1561-1574.
41. Platani, M., I. Goldberg, A.I. Lamond, and J.R. Swedlow. 2002. Cajal body dynamics and association with chromatin are ATP-dependent. Nat. Cell Biol. 4:502-508.
42. Pluk, H., J. Soffner, R. Luhrmann, and W. J. van Venrooij. 1998. cDNA cloning and characterization of the human U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein. Mol. Cell. Biol. 18:488-498.
43. Pogacic, V., F. Dragon, and W. Filipowicz. 2000. Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. Mol. Cell. Biol. 20:9028-9040.
44. Raska, I., L.E. Andrade, R.L. Ochs, E.K. Chan, C.M. Chang, G. Roos, and E.M. Tan. 1991. Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies. Exp. Cell Res. 195:27-37.
45. Shpargel, K.B., J.K. Ospina, K.E. Tucker, A.G. Matera, and M.D. Hebert. 2003. Control of Cajal body number is mediated by the coilin C-terminus. J. Cell Sci. 116:303-312.
46. Sleeman, J.E., and A.I. Lamond. 1999a. Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr. Biol. 9:1065-1074.
47. Sleeman, J.E., and A.I. Lamond. 1999b. Nuclear organization of pre-mRNA splicing factors. Curr. Opin. Cell Biol. 11:372-377.
48. Sleeman, J., C.E. Lyon, M. Platani, J.P. Kreivi, and A.I. Lamond. 1998. Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein. Exp. Cell Res. 243:290-304.
49. Sleeman, J.E., P. Ajuh, and A.I. Lamond. 2001. snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN. J. Cell Sci. 114:4407-4419.
50. Sleeman, J.E., L. Trinkle-Mulcahy, A.R. Prescott, S.C. Ogg, and A.I. Lamond. 2003. Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo. J. Cell Sci. 116:2039-2050.
51. Snaar, S., K. Wiesmeijer, A.G. Jochemsen, H.J. Tanke, and R.W. Dirks. 2000. Mutational analysis of fibrillarin and its mobility in living human cells. J. Cell Biol. 151:653-662.
52. Stanek, D., S.D. Rader, M. Klingauf, and K.M. Neugebauer. 2003. Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies. J. Cell Biol. 160:505-516.
53. Szebeni, A., K. Hingorani, S. Negi, and M.O. Olson. 2003. Role of protein kinase CK2 phosphorylation in the molecular chaperone activity of nucleolar protein b23. J. Biol. Chem. 278:9107-9115.
54. Tucker, K.E., M.T. Berciano, E.Y. Jacobs, D.F. LePage, K.B. Shpargel, J.J. Rossire, E.K. Chan, M. Lafarga, R.A. Conlon, and A.G. Matera. 2001. Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product. J. Cell Biol. 154:293-307.
55. Verheggen, C., D.L. Lafontaine, D. Samarsky, J. Mouaikel, J.M. Blanchard, R. Bordonne, and E. Bertrand. 2002. Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments. EMBO J. 21:2736-2745.
56. Wei, Y., J. Jin, and J.W. Harper. 2003. The cyclin E/Cdk2 substrate and Cajal body component p220(NPAT) activates histone transcription through a novel LisH-like domain. Mol. Cell. Biol. 23:3669-3680.
57. Young, P.J., T.T. Le, N. thi Man, A.H. Burghes, and G.E. Morris. 2000. The relationship between SMN, the spinal muscular atrophy protein, and nuclear coiled bodies in differentiated tissues and cultured cells. Exp. Cell Res. 256: 365-374.
58. Young, P.J., T.T. Le, M. Dunckley, T.M. Nguyen, A.H. Burghes, and G.E. Morris. 2001. Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN. Exp. Cell Res. 265:252-261.
59. Zhu, Y., R.L. Tomlinson, A.A. Lukowiak, R.M. Terns, and M.P. Terns. 2004. Telomerase RNA accumulates in Cajal bodies in human cancer cells. Mol. Biol. Cell. 15:81-90.