-
1
-
-
0025173604
-
Structure of spliceosomai snRNPs and their role in pre-mRNA splicing
-
Lührmann R, Kastner B, Bach M: Structure of spliceosomai snRNPs and their role in pre-mRNA splicing. Biochem Biophys Acta 1990, 1087:265-292.
-
(1990)
Biochem Biophys Acta
, vol.1087
, pp. 265-292
-
-
Lührmann, R.1
Kastner, B.2
Bach, M.3
-
2
-
-
0031834613
-
The cellular organization of gene expression
-
Misteli T, Spector DL: The cellular organization of gene expression. Curr Opin Cell Biol 1998, 10:323-331.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 323-331
-
-
Misteli, T.1
Spector, D.L.2
-
3
-
-
0032231895
-
Coiled bodies and gems: Janus or gemini?
-
Matera AG, Frey MR: Coiled bodies and gems: Janus or gemini? Am J Hum Genet 1998, 63:317-321.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 317-321
-
-
Matera, A.G.1
Frey, M.R.2
-
4
-
-
0031804377
-
Of coiled bodies, gems, and salmon
-
Matera AG: Of coiled bodies, gems, and salmon. J Cell Biochem 1998, 70:181-192.
-
(1998)
J Cell Biochem
, vol.70
, pp. 181-192
-
-
Matera, A.G.1
-
5
-
-
0032562608
-
Structure and function in the nucleus
-
Lamond AI, Earnshaw WC: Structure and function in the nucleus. Science 1998, 280:547-553.
-
(1998)
Science
, vol.280
, pp. 547-553
-
-
Lamond, A.I.1
Earnshaw, W.C.2
-
6
-
-
0032576729
-
Ribonucleoprotein assembly: Clues from spinal muscular atrophy
-
Mattaj IW: Ribonucleoprotein assembly: Clues from spinal muscular atrophy. Curr Biol 1998, 8:R93-R95.
-
(1998)
Curr Biol
, vol.8
-
-
Mattaj, I.W.1
-
7
-
-
0032169650
-
The plurifunctional nucleolus
-
Pederson T: The plurifunctional nucleolus. Nucleic Acids Res 1998, 26:3871-3876.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3871-3876
-
-
Pederson, T.1
-
8
-
-
0031860708
-
Nuclear neighbours: The spatial and functional organization of genes and nuclear domains
-
Shul W, de Jong L, van Driel R: Nuclear neighbours: The spatial and functional organization of genes and nuclear domains. J Cell Biochem 1998, 70:159-171.
-
(1998)
J Cell Biochem
, vol.70
, pp. 159-171
-
-
Shul, W.1
De Jong, L.2
Van Driel, R.3
-
9
-
-
0027651654
-
Localization of splicing snRNPs in mammalian-cells
-
Lamond AI, Carmo-Fonseca M: Localization of splicing snRNPs in mammalian-cells. Mol Biol Rep 1993, 18:127-133.
-
(1993)
Mol Biol Rep
, vol.18
, pp. 127-133
-
-
Lamond, A.I.1
Carmo-Fonseca, M.2
-
10
-
-
0027135889
-
Macromolecular domains within the cell nucleus
-
Spector DL: Macromolecular domains within the cell nucleus. Annu Rev Cell Biol 1993, 9:265-315.
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 265-315
-
-
Spector, D.L.1
-
11
-
-
0031005765
-
The dynamic organization of the perinucleolar compartment in the cell nucleus
-
Huang S, Deerinck TJ, Ellisman MH, Spector DL: The dynamic organization of the perinucleolar compartment in the cell nucleus. J Cell Biol 1997, 137:965-974.
-
(1997)
J Cell Biol
, vol.137
, pp. 965-974
-
-
Huang, S.1
Deerinck, T.J.2
Ellisman, M.H.3
Spector, D.L.4
-
12
-
-
1842376906
-
The dynamics of a pre-mRNA splicing factor in living cells
-
Misteli T, Caceres JF, Spector DL: The dynamics of a pre-mRNA splicing factor in living cells. Nature 1997, 387:523-527.
-
(1997)
Nature
, vol.387
, pp. 523-527
-
-
Misteli, T.1
Caceres, J.F.2
Spector, D.L.3
-
13
-
-
0032531261
-
Dynamic interactions between splicing snRnps, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein
-
Sleeman J, Lyon CE, Platani M, Kreivi J-P, Lamond AI: Dynamic interactions between splicing snRnps, coiled bodies and nucleoli revealed using snRnp protein fusions to the green fluorescent protein. Exp Cell Res 1998, 243:290-304. Shows that protein phosphorylation may control snRNP interactions with the coiled body and nucleolus using GFP fusion proteins in living cells. Inhibition of protein phosphatase activity, or expression of a mutant of p80-coilin mimicking permanent serine phosphorylation, results in the accumulation of snRNP proteins inside the nucleolus.
-
(1998)
Exp Cell Res
, vol.243
, pp. 290-304
-
-
Sleeman, J.1
Lyon, C.E.2
Platani, M.3
Kreivi, J.-P.4
Lamond, A.I.5
-
14
-
-
0031711073
-
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
-
Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M: Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat Genet 1998, 20:46-50. Uses a combination ot nanoelectrospray mass spectrometry of purified spliceosomes with EST (expressed sequence tag) database searching to identify many new nuclear proteins that form stable associations with human splicing complexes.
-
(1998)
Nat Genet
, vol.20
, pp. 46-50
-
-
Neubauer, G.1
King, A.2
Rappsilber, J.3
Calvio, C.4
Watson, M.5
Ajuh, P.6
Sleeman, J.7
Lamond, A.8
Mann, M.9
-
15
-
-
0027183212
-
Separation of splicing factor SF3 into two components and purification of SF3a activity
-
Brosi R, Hauri HP, Kramer A: Separation of splicing factor SF3 into two components and purification of SF3a activity. J Biol Chem 1993, 268:17640-17646.
-
(1993)
J Biol Chem
, vol.268
, pp. 17640-17646
-
-
Brosi, R.1
Hauri, H.P.2
Kramer, A.3
-
16
-
-
0031885702
-
Molecular characterization of a novel, widespread nuclear protein that colocalizes with spliceosome components
-
Schmidt-Zachmann MS, Knecht S, Kramer A: Molecular characterization of a novel, widespread nuclear protein that colocalizes with spliceosome components. Mol Biol Cell 1998, 9:143-160.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 143-160
-
-
Schmidt-Zachmann, M.S.1
Knecht, S.2
Kramer, A.3
-
17
-
-
0031049977
-
Transcription-dependent redistribution of nuclear protein 4.1 to SC35-enriched nuclear domains
-
Lallena MJ, Correas I: Transcription-dependent redistribution of nuclear protein 4.1 to SC35-enriched nuclear domains. J Cell Sci 1997, 110:239-247.
-
(1997)
J Cell Sci
, vol.110
, pp. 239-247
-
-
Lallena, M.J.1
Correas, I.2
-
18
-
-
0031846441
-
Functional association of nuclear protein 4.1 with pre-mRNA splicing factors
-
Lallena M, Martinez C, Valcarcel J, Correas I: functional association of nuclear protein 4.1 with pre-mRNA splicing factors. J Cell Sci 1998, 111:1963-1971. Identifies a nuclear isoform of protein 4.1 as a possible structural component of 'speckles'. Antibodies to protein 4.1 immunoprecipitate a number of snRNP and non-snRNP protein splicing factors. Overexpression of isoform 4.1E results in redistribution of the splicing factor SC-35.
-
(1998)
J Cell Sci
, vol.111
, pp. 1963-1971
-
-
Lallena, M.1
Martinez, C.2
Valcarcel, J.3
Correas, I.4
-
19
-
-
0032494088
-
The hrp23 protein in the Balbiani ring pre-mRNP particles is released just before or at the binding of the particles to the nuclear pore complex
-
Sun X, Alzhanova-Ericsson AT, Visa N, Aissouni Y, Zhao J, Daneholt B: The hrp23 protein in the Balbiani ring pre-mRNP particles is released just before or at the binding of the particles to the nuclear pore complex. J Cell Biol 1998, 142:1181-1193. Characterizes a novel protein, hrp23, and uses immunoelectron microscopy to show that it accompanies mRNP particles from transcription sites to the nuclear pore complex.
-
(1998)
J Cell Biol
, vol.142
, pp. 1181-1193
-
-
Sun, X.1
Alzhanova-Ericsson, A.T.2
Visa, N.3
Aissouni, Y.4
Zhao, J.5
Daneholt, B.6
-
20
-
-
0029923029
-
Neuronal differentiation in the rat hippocampus involves a stage-specific reorganization of subnuclear structure both in vivo and in vitro
-
Santama N, Dotti CG, Lamond AI: Neuronal differentiation in the rat hippocampus involves a stage-specific reorganization of subnuclear structure both in vivo and in vitro. Eur J Neurosci 1996, 8:892-905.
-
(1996)
Eur J Neurosci
, vol.8
, pp. 892-905
-
-
Santama, N.1
Dotti, C.G.2
Lamond, A.I.3
-
21
-
-
0031924033
-
Changes in the nucleolar and coiled body compartments precede lamina and chromatin reorganization during fibre cell denucleation in the bovine lens
-
Dahm R, Gribbon C, Quinlan RA, Prescott AR: Changes in the nucleolar and coiled body compartments precede lamina and chromatin reorganization during fibre cell denucleation in the bovine lens. Eur J Cell Biol 1998, 75:237-246.
-
(1998)
Eur J Cell Biol
, vol.75
, pp. 237-246
-
-
Dahm, R.1
Gribbon, C.2
Quinlan, R.A.3
Prescott, A.R.4
-
22
-
-
0032428592
-
Coiled body numbers in the Arabidopsis root epidermis are regulated by cell type, developmental stage and cell cycle parameters
-
Boudonck K, Dolan L, Shaw PJ: Coiled body numbers in the Arabidopsis root epidermis are regulated by cell type, developmental stage and cell cycle parameters. J Cell Sci 1998, 111:3687-3694.
-
(1998)
J Cell Sci
, vol.111
, pp. 3687-3694
-
-
Boudonck, K.1
Dolan, L.2
Shaw, P.J.3
-
23
-
-
0033545387
-
Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts
-
Frey MR, Bailey AD, Weiner AM, Matera AG: Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts. Curr Biol 1999, 9:126-135. Artificial tandem arrays of human U1 and U2 snRNA genes are shown to associate with coiled bodies in stable cell lines using simultaneous immunofluorescence and in situ hybridization. The use of transcriptionally inactive promoter mutants or the replacement of U2 coding regions with heterologous sequences suggests that the association of coiled bodies with the U2 snRNA gene arrays is mediated by the nascent U2 snRNA.
-
(1999)
Curr Biol
, vol.9
, pp. 126-135
-
-
Frey, M.R.1
Bailey, A.D.2
Weiner, A.M.3
Matera, A.G.4
-
24
-
-
0030793104
-
The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies
-
Jordan P, Cunha C, Carmo-Fonseca M: The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies. Mol Biol Cell 1997, 8:1207-1 217.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1207-1217
-
-
Jordan, P.1
Cunha, C.2
Carmo-Fonseca, M.3
-
25
-
-
0031667334
-
Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription
-
Schul W, van Driel R, de Jong L: Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription. Mol Biol Cell 1998, 9:1025-1036. Uses immunofluorescent labelling of human cells to demonstrate the concentration of factors required for snRNA transcription in coiled bodies. The γ-subunit of the snRNA-specific transcription factor PTF (proximal element sequence-binding transcription factor) was detected in coiled bodies, together with the general transcription factor, TATA-box binding protein (TBP), and a subset of RNA polymerase II.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1025-1036
-
-
Schul, W.1
Van Driel, R.2
De Jong, L.3
-
26
-
-
0029447814
-
Molecular analysis of the coiled body
-
Bohmann K, Ferreira J, Santama N, Weis K, Lamond AI: Molecular analysis of the coiled body. J Cell Sci 1995, 19:107-113.
-
(1995)
J Cell Sci
, vol.19
, pp. 107-113
-
-
Bohmann, K.1
Ferreira, J.2
Santama, N.3
Weis, K.4
Lamond, A.I.5
-
27
-
-
0028882193
-
Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus
-
Bohmann K, Ferreira JA, Lamond AI: Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus. J Cell Biol 1995, 131:817-831.
-
(1995)
J Cell Biol
, vol.131
, pp. 817-831
-
-
Bohmann, K.1
Ferreira, J.A.2
Lamond, A.I.3
-
28
-
-
0032572411
-
Nopp1 40 functions as a molecular link between the nucleolus and the coiled bodies
-
Isaac C, YAng Y, Meier UT: Nopp1 40 functions as a molecular link between the nucleolus and the coiled bodies. J Cell Biol 1998, 142:319-329. Transient transfection of epitope-tagged mutants of the nucleolar protein Nopp140 into human cell lines affects the structure of both nucleoli and coiled bodies. A yeast two-hybrid screen with Nopp140 indicates that the coiled body protein, p80-coilin, interacts with Nopp140. Co-immunoprecipitation studies confirm an interaction between the two proteins.
-
(1998)
J Cell Biol
, vol.142
, pp. 319-329
-
-
Isaac, C.1
Yang, Y.2
Meier, U.T.3
-
29
-
-
0032214692
-
Modification of U6 splicosomal RNA is guided by other small RNAs
-
Tycowski KT, You Z, Graham PJ, Steitz JA: Modification of U6 splicosomal RNA is guided by other small RNAs. Mol Cell 1998, 2:629-638. A novel, conserved small RNA, mgU6-77, can direct 2′-O-methylation of U6 snRNA and 28S rRNA. Depletion of mgU6-77 from Xenopus oocytes prevents this methylation, while the injection of in vitro transcribed mgU6-77 restores the methylation activity.
-
(1998)
Mol Cell
, vol.2
, pp. 629-638
-
-
Tycowski, K.T.1
You, Z.2
Graham, P.J.3
Steitz, J.A.4
-
30
-
-
0031667098
-
Acute osmotic/ stress stimuli induce a transient decrease of transriptional activity in the neurosecretory neurons of supraoptic nuclei
-
Lafarga M, Berciano MT, Garcia-Segura LM, Andres MA, Carmo-Fonseca M: Acute osmotic/ stress stimuli induce a transient decrease of transriptional activity in the neurosecretory neurons of supraoptic nuclei. J Neurocyt 1998, 27:205-217.
-
(1998)
J Neurocyt
, vol.27
, pp. 205-217
-
-
Lafarga, M.1
Berciano, M.T.2
Garcia-Segura, L.M.3
Andres, M.A.4
Carmo-Fonseca, M.5
-
31
-
-
0027324153
-
Identification and characterization of a sphere organelle protein
-
Tuma R, Stolk JA, Roth MB: Identification and characterization of a sphere organelle protein. J Cell Biol 1993, 122:767-773.
-
(1993)
J Cell Biol
, vol.122
, pp. 767-773
-
-
Tuma, R.1
Stolk, J.A.2
Roth, M.B.3
-
32
-
-
0028072742
-
Human p80-coilin is targeted to sphere organelles in the amphibian germinal vesicle
-
Wu ZA, Murphy C, Gall JG: Human p80-coilin is targeted to sphere organelles in the amphibian germinal vesicle. Mol Biol Cell 1994, 5:1119-1127.
-
(1994)
Mol Biol Cell
, vol.5
, pp. 1119-1127
-
-
Wu, Z.A.1
Murphy, C.2
Gall, J.G.3
-
33
-
-
0031667189
-
Coilin can form a complex with the U7 small nuclear ribonucleoprotein
-
Bellini M, Gall JG: Coilin can form a complex with the U7 small nuclear ribonucleoprotein. Mol Biol Cell 1998, 9:2987-3001. Shows that a Xenopus p80-coilin homologue can bind U7 snRNP and nucleic acids.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2987-3001
-
-
Bellini, M.1
Gall, J.G.2
-
34
-
-
0029064131
-
Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells
-
Frey MR, Matera AG: Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells. Proc Natl Acad Sci USA 1995, 92:5915-5919.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5915-5919
-
-
Frey, M.R.1
Matera, A.G.2
-
35
-
-
0025888958
-
Histone genes are located at the sphere loci of Xenopus lampbrush chromosomes
-
Callan HG, Gall JG, Murphy C: Histone genes are located at the sphere loci of Xenopus lampbrush chromosomes. Chromosoma 1991, 101:245-251.
-
(1991)
Chromosoma
, vol.101
, pp. 245-251
-
-
Callan, H.G.1
Gall, J.G.2
Murphy, C.3
-
36
-
-
0031821085
-
Protein heterogeneity in the coiled body compartment
-
Alliegro MC, Alliegro MA: Protein heterogeneity in the coiled body compartment. Exp Cell Res 1998, 239:60-68. Uses immunofluorescent labelling of bovine cells to provide evidence that the protein composition of coiled bodies can vary. Fibrillarin and pigpen are both demonstrated to be present in only a subset of nuclear coiled bodies.
-
(1998)
Exp Cell Res
, vol.239
, pp. 60-68
-
-
Alliegro, M.C.1
Alliegro, M.A.2
-
37
-
-
0029954338
-
A novel nuclear structure containing the survival of motor neurons protein
-
Liu Q, Dreyfuss G: A novel nuclear structure containing the survival of motor neurons protein. EMBO J 1996, 15:3555-3565.
-
(1996)
EMBO J
, vol.15
, pp. 3555-3565
-
-
Liu, Q.1
Dreyfuss, G.2
-
38
-
-
0030931727
-
The spinal muscular atrophy gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins
-
Liu Q, Fischer U, Wang F, Dreyfuss G: The spinal muscular atrophy gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRnp proteins. Cell 1997, 90:1013-1021.
-
(1997)
Cell
, vol.90
, pp. 1013-1021
-
-
Liu, Q.1
Fischer, U.2
Wang, F.3
Dreyfuss, G.4
-
39
-
-
0030928716
-
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis
-
Fischer U, Liu Q, Dreyfuss G: The SMN-SIP1 complex has an essential role in spliceosomal snRnp biogenesis. Cell 1997, 90:1023-1029.
-
(1997)
Cell
, vol.90
, pp. 1023-1029
-
-
Fischer, U.1
Liu, Q.2
Dreyfuss, G.3
-
40
-
-
0029756583
-
Transcriptional pulse-chase analysis reveals a role for a novel snRnp-associated protein in the manufacture of spliceosomal snRnps
-
Noble SM, Guthrie C: Transcriptional pulse-chase analysis reveals a role for a novel snRnp-associated protein in the manufacture of spliceosomal snRnps. EMBO J 1996, 15:4368-4379.
-
(1996)
EMBO J
, vol.15
, pp. 4368-4379
-
-
Noble, S.M.1
Guthrie, C.2
-
41
-
-
0032567036
-
A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing
-
Pellizzoni L, Katoka N, Charroux B, Dreyfuss G: A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing. Cell 1998, 95:615-624. Transient expression of an epitope-tagged mutant of the SMN protein in human cells results in re-organization of snRNPs and p80-coilin within the nucleus. The same mutant inhibits mRNA splicing in vitro.
-
(1998)
Cell
, vol.95
, pp. 615-624
-
-
Pellizzoni, L.1
Katoka, N.2
Charroux, B.3
Dreyfuss, G.4
-
42
-
-
0031128181
-
Protein phosphorylation and the nuclear organization of pre-mRNA splicing
-
Misteli T, Spector DL: Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends Cell Biol 1997, 7:135-138.
-
(1997)
Trends Cell Biol
, vol.7
, pp. 135-138
-
-
Misteli, T.1
Spector, D.L.2
-
43
-
-
0028286596
-
A serine kinase regulates intracellular localization of splicing factors in the cell cycle
-
Gui JF, Lane WS, Fu XD: A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature 1994, 369:678-682.
-
(1994)
Nature
, vol.369
, pp. 678-682
-
-
Gui, J.F.1
Lane, W.S.2
Fu, X.D.3
-
44
-
-
0028043718
-
Regulation of mammalian spliceosome assembly by a protein-phosphorylatlon mechanism
-
Mermoud JE, Cohen PTW, Lamond AI: Regulation of mammalian spliceosome assembly by a protein-phosphorylatlon mechanism. EMBO J 1994, 13:5679-5688.
-
(1994)
EMBO J
, vol.13
, pp. 5679-5688
-
-
Mermoud, J.E.1
Cohen, P.T.W.2
Lamond, A.I.3
-
45
-
-
0030028882
-
The Clk/Sty protein kinase phosphorylates splicing factors and regulates their intranuclear distribution
-
Colwill K, Pawson T, Andrews B, Prasad J, Manley JL, Bell JC, Duncan PI: The Clk/Sty protein kinase phosphorylates splicing factors and regulates their intranuclear distribution. EMBO J 1996, 15:265-275.
-
(1996)
EMBO J
, vol.15
, pp. 265-275
-
-
Colwill, K.1
Pawson, T.2
Andrews, B.3
Prasad, J.4
Manley, J.L.5
Bell, J.C.6
Duncan, P.I.7
-
46
-
-
0029798802
-
Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors
-
Misteli T, Spector DL: Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors. Mol Biol Cell 1996, 7:1559-1572.
-
(1996)
Mol Biol Cell
, vol.7
, pp. 1559-1572
-
-
Misteli, T.1
Spector, D.L.2
-
47
-
-
0032526770
-
The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing
-
Duncan PI, Stojdl DF, Marius RM, Scheit KH, Bell JC: The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing. Exp Cell Res 1998, 241:300-308.
-
(1998)
Exp Cell Res
, vol.241
, pp. 300-308
-
-
Duncan, P.I.1
Stojdl, D.F.2
Marius, R.M.3
Scheit, K.H.4
Bell, J.C.5
-
48
-
-
0032515325
-
Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles
-
Kuroyanagi N, Onogi H, Wakabayashi T, Hagiwara M: Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles. Biophys Res Commun 1998, 14:357-364.
-
(1998)
Biophys Res Commun
, vol.14
, pp. 357-364
-
-
Kuroyanagi, N.1
Onogi, H.2
Wakabayashi, T.3
Hagiwara, M.4
-
49
-
-
0032559642
-
Fu X-D: SRPK2: A differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells
-
Wang H-Y, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, Fu X-D: SRPK2: A differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. J Cell Biol 1998, 140:737-750. The authors characterize a new SR protein kinase and its differential tissue expression. SRPK2 can phosphorylate SR proteins in vitro. Overexpression of GFP-tagged SRPK1 induces specific redistribution of splicing factors in the nucleus. Northern blot analysis demonstrates a high level of SRPK2 expression in the brain, whereas the related protein kinase, SRPK1, is highly expressed in pancreas.
-
(1998)
J Cell Biol
, vol.140
, pp. 737-750
-
-
Wang, H.-Y.1
Lin, W.2
Dyck, J.A.3
Yeakley, J.M.4
Songyang, Z.5
Cantley, L.C.6
-
50
-
-
15844415445
-
Specific phosphorylation of SR proteins by mammalian topoisomerase I
-
Rossi F, Labourier E, Forne T, Divita G, Derancourt J, Riou JF, Antoine E, Cathala G, Brunel C, Tazi J: Specific phosphorylation of SR proteins by mammalian topoisomerase I. Nature 1996, 381:80-82.
-
(1996)
Nature
, vol.381
, pp. 80-82
-
-
Rossi, F.1
Labourier, E.2
Forne, T.3
Divita, G.4
Derancourt, J.5
Riou, J.F.6
Antoine, E.7
Cathala, G.8
Brunel, C.9
Tazi, J.10
-
51
-
-
0032547829
-
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo
-
Misteli T, Caceres JF, Clement JQ, Krainer AR, Wilkinson MF, Spector DL: Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J Cell Biol 1998, 143:297-307. Transient expression of various deletion mutants of the SR protein ASF/SF2 shows that multiple protein domains are required for efficient recruitment of SR proteins from 'speckles' to nascent RNA. Replacement of the RS-dipeptides, which are subject to serine phosphorylation, with RG-dipeptides abolishes ASF/SF2 recruitment to nascent RNA, demonstrating that serine phosphorylation is required for recruitment.
-
(1998)
J Cell Biol
, vol.143
, pp. 297-307
-
-
Misteli, T.1
Caceres, J.F.2
Clement, J.Q.3
Krainer, A.R.4
Wilkinson, M.F.5
Spector, D.L.6
-
52
-
-
0031561729
-
Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus
-
Lyon CE, Bohmann K, Sleeman J, Lamond AI: Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus. Exp Cell Res 1997, 230:84-93.
-
(1997)
Exp Cell Res
, vol.230
, pp. 84-93
-
-
Lyon, C.E.1
Bohmann, K.2
Sleeman, J.3
Lamond, A.I.4
-
53
-
-
0029083171
-
Subunit structure and regulation of protein phosphatase-I in rat liver nuclei
-
Jagiello I, Beullens M, Stalmans W, Bollen M: Subunit structure and regulation of protein phosphatase-I in rat liver nuclei. J Biol Chem 1995, 270:17257-17263.
-
(1995)
J Biol Chem
, vol.270
, pp. 17257-17263
-
-
Jagiello, I.1
Beullens, M.2
Stalmans, W.3
Bollen, M.4
-
54
-
-
0031583952
-
Purification and characterization of p99, a nuclear modulator of protein phosphatase I activity
-
Kreivi J-P, Trinkle-Mulcahy L, Lyon CE, Morrice NA, Cohen P, Lamond AI: Purification and characterization of p99, a nuclear modulator of protein phosphatase I activity. FEBS Lett 1997, 420:57-62.
-
(1997)
FEBS Lett
, vol.420
, pp. 57-62
-
-
Kreivi, J.-P.1
Trinkle-Mulcahy, L.2
Lyon, C.E.3
Morrice, N.A.4
Cohen, P.5
Lamond, A.I.6
-
55
-
-
0032512720
-
Isolation and characterization of PNUTS, a putative protein phosphatase I nuclear targeting subunit
-
Allen PB, Kwon YG, Nairn AC, Greenguard P: Isolation and characterization of PNUTS, a putative protein phosphatase I nuclear targeting subunit. J Biol Chem 1998, 273:4089-4095.
-
(1998)
J Biol Chem
, vol.273
, pp. 4089-4095
-
-
Allen, P.B.1
Kwon, Y.G.2
Nairn, A.C.3
Greenguard, P.4
-
56
-
-
0028825490
-
Molecular cloning of NIPP-I, a nuclear inhibitor of protein phosphatase-i, reveals homology with polypeptides involved in RNA processing
-
Van Eynde A, Wera S, Beullens M, Torrekens S, Van Leuven F. Stalmans W, Bollen M: Molecular cloning of NIPP-I, a nuclear inhibitor of protein phosphatase-i, reveals homology with polypeptides involved in RNA processing. J Biol Chem 1995, 270:28068-28074.
-
(1995)
J Biol Chem
, vol.270
, pp. 28068-28074
-
-
Van Eynde, A.1
Wera, S.2
Beullens, M.3
Torrekens, S.4
Van Leuven, F.5
Stalmans, W.6
Bollen, M.7
-
57
-
-
0032994412
-
Nuclear organization of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors
-
Trinkle-Mulcahy L, Ajuh P, Prescott A, Claverie-Martin F, Cohen S, Lamond AI, Cohen P: Nuclear organization of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors. J Cell Sci 1999, 112:157-168. A combination of immunofluorescent labeling of human cell lines and in vitro analyses of protein interactions shows that a nuclear PPI regulating protein, NIPP1 (nuclear inhibitor of PP1) can associate with splicing factors. Immunodepletion of NIPP1 from nuclear extracts results in greatly reduced in vitro splicing activity.
-
(1999)
J Cell Sci
, vol.112
, pp. 157-168
-
-
Trinkle-Mulcahy, L.1
Ajuh, P.2
Prescott, A.3
Claverie-Martin, F.4
Cohen, S.5
Lamond, A.I.6
Cohen, P.7
-
58
-
-
0031877713
-
Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells
-
Seghezzi W, Chua K, Shanahan F, Gozani O, Reed R, Lees E: Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells. Mol Cell Biol 1998, 18:4526-4536. Cyclin-E specific antibodies co-immunoprecipitate a number of snRNP and non-snRNP protein splicing factors. As cyclin-E is a critical regulator of cell cycle progression from G1 into S-phase in mammalian cells, the authors suggest that splicing might be regulated by the cell-cycle machinery.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4526-4536
-
-
Seghezzi, W.1
Chua, K.2
Shanahan, F.3
Gozani, O.4
Reed, R.5
Lees, E.6
-
59
-
-
0025115231
-
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus
-
Fu XD, Maniatis T: Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature 1990, 343:437-441.
-
(1990)
Nature
, vol.343
, pp. 437-441
-
-
Fu, X.D.1
Maniatis, T.2
-
60
-
-
0026751769
-
Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA
-
Kambach C, Mattaj IW: Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA. J Cell Biol 1992, 118:11-21.
-
(1992)
J Cell Biol
, vol.118
, pp. 11-21
-
-
Kambach, C.1
Mattaj, I.W.2
-
61
-
-
0021345835
-
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1) ribonucleoprotein and anti-Sm autoantibodies
-
Pettersson I, Hinterberger M, Mimori T, Gottlieb E, Steitz JA: The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1) ribonucleoprotein and anti-Sm autoantibodies. J Biol Chem 1984, 259:5907-5914.
-
(1984)
J Biol Chem
, vol.259
, pp. 5907-5914
-
-
Pettersson, I.1
Hinterberger, M.2
Mimori, T.3
Gottlieb, E.4
Steitz, J.A.5
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