Sustained multilineage gene persistence and expression in dogs transplanted with CD34+ marrow cells transduced by RD114-pseudotype oncoretrovirus vectors

Blood

Volumn 98, Issue 7, 2001, Pages 2065-2070

  Goerner, Martin ^a,b   Horn, Peter A ^a,b   Peterson, Laura ^a,b   Kurre, Peter ^a,b   Storb, Rainer ^a,b   Rasko, John E J ^a,b   Kiem, Hans Peter ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; ENVELOPE PROTEIN; GREEN FLUORESCENT PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; DEATH; DISEASE MODEL; DOG; FLOW CYTOMETRY; FOLLOW UP; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; MARKER GENE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; VIRUS EXPRESSION; VIRUS STRAIN;

EID: 0035496914     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.7.2065     Document Type: Article

References (22)

1. Kiem H-P, Heyward S, Winkler A, et al. Gene transfer into marrow repopulating cells: comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons. Blood. 1997;90:4638-4645.
2. Kiem H-P, Andrews RG, Morris J, et al. Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor. Blood. 1998;92: 1878-1886.
3. Dunbar CE, Seidel NE, Doren S, et al. Improved retroviral gene transfer into murine and rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor. Proc Natl Acad Sci U S A. 1996;93:11871-11876.
4. Tisdale JF, Hanazono Y, Sellers SE, et al. Ex vivo expansion of genetically marked Rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability. Blood. 1998;92: 1131-1141.
5. Kiem H-P, McSweeney PA, Bruno B, et al. Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus-pseudotype retroviral vector. Gene Ther. 1999;6:966-972.
6. Goerner M, Bruno B, McSweeney PA, Buron G, Storb R, Kiem H-P. The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs. Blood. 1999;94:2287-2292.
7. Kurre P, Kiem H-P, Morris J, Heyward S, Battini J-L, Miller AD. Efficient transduction by an am photropic retrovirus vector is dependent on high-level expression of the cell surface virus receptor. J Virol. 1999;73:495-500.
8. Orlic D, Girard LJ, Anderson SM, et al. Transduction efficiency of cell lines and hematopoietic stem cells correlates with retrovirus receptor mRNA levels. Stem Cells. 1997;15(suppl 1):23-28.
9. Orlic D, Girard LJ, Jordan CT, Anderson SM, Cline AP, Bodine DM. The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction. Proc Natl Acad Sci U S A. 1996;93: 11097-11102.
10. + cells emphasize limited transduction at low receptor levels. Gene Ther. 2001;8: 593-599.
11. Cosset FL, Takeuchi Y, Battini JL, Weiss RA, Collins MKL. High-titer packaging cells producing recombinant retroviruses resistant to human serum. J Virol. 1995;69:7430-7436.
12. Onodera M, Nelson DM, Yachie A, et al. Development of improved adenosine deaminase retroviral vectors. J Virol. 1998;72:1769-1774.
13. Kelly PF, Vandergriff J, Nathwani A, Nienhuis AW, Vanin EF. Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. Blood. 2000;96:1206-1214.
14. Porter CD, Collins MK, Tailor CS, et al. Comparison of efficiency of infection of human gene therapy target cells via four different retroviral receptors. Hum Gene Ther. 1996;7:913-919.
15. Bauer TR Jr, Miller AD, Hickstein DD. Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines using retroviral vectors having a gibbon ape leukemia virus envelope. Blood. 1995;86:2379-2387.
16. Miller AD, Garcia JV, von Suhr N, Lynch CM, Wilson C, Eiden MV. Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol. 1991;65:2220-2224.
17. McSweeney PA, Rouleau KA, Wallace PM, et al. Characterization of monoclonal antibodies that recognize canine CD34. Blood. 1998;91:1977-1986.
18. Sandmaier BM, Schuening FG, Bianco JA, et al. Biochemical characterization of a unique canine myeloid antigen. Leukemia. 1991;5:125-130.
19. Rasko JEJ, Battini J-L, Gottschalk RJ, Mazo I, Miller AD. The RD114/simian type D retrovirus receptor is a neutral amino acid transporter. Proc Natl Acad Sci U S A. 1999;96:2129-2134.
20. Forestell SP, Dando JS, Chen J, de Vries P, Bohnlein E, Rigg RJ. Novel retroviral packaging cell lines: complementary tropisms and improved vector production for efficient gene transfer. Gene Ther. 1997;4:600-610.
21. Davis JL, Witt RM, Gross PR, et al. Retroviral particles produced from a stable human-derived packaging cell line transduce target cells with very high efficiencies. Hum Gene Ther. 1997;8: 1459-1467.
22. Le Doux JM, Morgan JR, Snow RG, Yarmush ML. Proteoglycans secreted by packaging cell lines inhibit retrovirus infection. J Virol. 1996;70:6468-6473.