-
1
-
-
10744225271
-
Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors
-
Antonescu CR, Sommer G, Sarran L, et al. Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors. Clin Cancer Res. 2003;9:3329-3337.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3329-3337
-
-
Antonescu, C.R.1
Sommer, G.2
Sarran, L.3
-
2
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
-
Buchdunger E, Cioffi CL, Law N, et al. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther. 2000; 295:139-145.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.L.2
Law, N.3
-
3
-
-
0036092268
-
KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size
-
Corless CL, McGreevey L, Haley A, et al. KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size. Am J Pathol. 2002;160:1567-1572.
-
(2002)
Am J Pathol
, vol.160
, pp. 1567-1572
-
-
Corless, C.L.1
McGreevey, L.2
Haley, A.3
-
4
-
-
0036795899
-
Approval summary: Imatinib mesylate in the treatment of metastatic and/ or unresectable malignant gastrointestinal stromal tumors
-
Dagher R, Cohen M, Williams G. et al. Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors. Clin Cancer Res. 2002;8:3034-3038.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3034-3038
-
-
Dagher, R.1
Cohen, M.2
Williams, G.3
-
5
-
-
0033984319
-
Two hundred gastrointestinal stromal tumors: Recurrence patterns and prognostic factors for survival
-
DeMatteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 2000;231:51-58.
-
(2000)
Ann Surg
, vol.231
, pp. 51-58
-
-
DeMatteo, R.P.1
Lewis, J.J.2
Leung, D.3
-
6
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
7
-
-
0032408616
-
KIT mutation portends poor prognosis in gastrointestinal stromal/smooth muscle tumors
-
Ernst SI, Hubbs AE, Przygodzki RM, et al. KIT mutation portends poor prognosis in gastrointestinal stromal/smooth muscle tumors. Lab Invest. 1998;78:1633-1636.
-
(1998)
Lab Invest
, vol.78
, pp. 1633-1636
-
-
Ernst, S.I.1
Hubbs, A.E.2
Przygodzki, R.M.3
-
8
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol. 2002;33:459-465.
-
(2002)
Hum Pathol
, vol.33
, pp. 459-465
-
-
Fletcher, C.D.1
Berman, J.J.2
Corless, C.3
-
9
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science. 2003;299:708-710.
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
10
-
-
0041971080
-
Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors
-
Hirota S, Ohashi A, Nishida T, et al. Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors. Gastroenterology. 2003;125:660-667.
-
(2003)
Gastroenterology
, vol.125
, pp. 660-667
-
-
Hirota, S.1
Ohashi, A.2
Nishida, T.3
-
11
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998;279:577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
-
12
-
-
0035066051
-
Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours
-
Hirota S, Nishida T, Isozaki K, et al. Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours. J Pathol. 2001;193:505-510.
-
(2001)
J Pathol
, vol.193
, pp. 505-510
-
-
Hirota, S.1
Nishida, T.2
Isozaki, K.3
-
13
-
-
0036319991
-
Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution
-
Hornick JL, Fletcher CD. Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution. Am J Clin Pathol. 2002;117:188-193.
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 188-193
-
-
Hornick, J.L.1
Fletcher, C.D.2
-
14
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med. 2001;344:1052-1056.
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
15
-
-
0242643600
-
Mechanisms of inactivation of the p16 gene in leiomyosarcoma of soft tissue: A decrease of p16 expression correlates with poor prognosis and the methylation status
-
in press
-
Kawaguchi K, Oda Y, Saito T, et al. Mechanisms of inactivation of the p16 gene in leiomyosarcoma of soft tissue: a decrease of p16 expression correlates with poor prognosis and the methylation status. J Pathol. 2003;(in press)
-
(2003)
J Pathol
-
-
Kawaguchi, K.1
Oda, Y.2
Saito, T.3
-
16
-
-
0033820064
-
Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors: A study of 200 cases
-
Lasota J, Wozniak A, Sarlomo-Rikala M, et al. Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors: a study of 200 cases. Am J Pathol. 2000;157:1091-1095.
-
(2000)
Am J Pathol
, vol.157
, pp. 1091-1095
-
-
Lasota, J.1
Wozniak, A.2
Sarlomo-Rikala, M.3
-
17
-
-
0032953812
-
Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas
-
Lasota J, Jasinski M, Sarlomo-Rikala M, et al. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol. 1999;154:53-60.
-
(1999)
Am J Pathol
, vol.154
, pp. 53-60
-
-
Lasota, J.1
Jasinski, M.2
Sarlomo-Rikala, M.3
-
18
-
-
0033883060
-
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors
-
Lux ML, Rubin BP, Biase TL, et al. KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. Am J Pathol. 2000;156:791-795.
-
(2000)
Am J Pathol
, vol.156
, pp. 791-795
-
-
Lux, M.L.1
Rubin, B.P.2
Biase, T.L.3
-
19
-
-
0036301863
-
Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: A review
-
Miettinen M, El-Rifai WHL, Sobin L, et al. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol. 2002; 33:478-483.
-
(2002)
Hum Pathol
, vol.33
, pp. 478-483
-
-
Miettinen, M.1
El-Rifai, W.H.L.2
Sobin, L.3
-
20
-
-
0033771977
-
Gastrointestinal stromal tumors and leiomyosarcomas in the colon: A clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases
-
Miettinen M, Sarlomo-Rikala M, Sobin LH, et al. Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. Am J Surg Pathol. 2000;24:1339-1352.
-
(2000)
Am J Surg Pathol
, vol.24
, pp. 1339-1352
-
-
Miettinen, M.1
Sarlomo-Rikala, M.2
Sobin, L.H.3
-
21
-
-
0035142836
-
Gastrointestinal stromal tumors: Definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
-
Miettinen M, Lasota J. Gastrointestinal stromal tumors: definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001;438:1-12.
-
(2001)
Virchows Arch
, vol.438
, pp. 1-12
-
-
Miettinen, M.1
Lasota, J.2
-
22
-
-
0032862462
-
Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: Clinicopathologic and immunohistochemical study of 26 cases
-
Miettinen M, Monihan JM, Sarlomo-Rikala M, et al. Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases. Am J Surg Pathol. 1999;23:1109-1118.
-
(1999)
Am J Surg Pathol
, vol.23
, pp. 1109-1118
-
-
Miettinen, M.1
Monihan, J.M.2
Sarlomo-Rikala, M.3
-
23
-
-
0033545568
-
Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors
-
Moskaluk CA, Tian Q, Marshall CR, et al. Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors. Oncogene. 1999;18:1897-1902.
-
(1999)
Oncogene
, vol.18
, pp. 1897-1902
-
-
Moskaluk, C.A.1
Tian, Q.2
Marshall, C.R.3
-
24
-
-
0035044154
-
The effect of surgery and grade on outcome of gastrointestinal stromal tumors
-
Pierie JP, Choudry U, Muzikansky A, et al. The effect of surgery and grade on outcome of gastrointestinal stromal tumors. Arch Surg. 2001; 136:383-389.
-
(2001)
Arch Surg
, vol.136
, pp. 383-389
-
-
Pierie, J.P.1
Choudry, U.2
Muzikansky, A.3
-
25
-
-
0034109008
-
Extragastrointestinal (soft tissue) stromal tumors: An analysis of 48 cases with emphasis on histologic predictors of outcome
-
Reith JD, Goldblum JR, Lyles RH, et al. Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome. Mod Pathol. 2000;13:577-585.
-
(2000)
Mod Pathol
, vol.13
, pp. 577-585
-
-
Reith, J.D.1
Goldblum, J.R.2
Lyles, R.H.3
-
26
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin BP, Singer S, Tsao C, et al. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res. 2001;61:8118-8121.
-
(2001)
Cancer Res
, vol.61
, pp. 8118-8121
-
-
Rubin, B.P.1
Singer, S.2
Tsao, C.3
-
27
-
-
0033372634
-
C-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal)
-
Sakurai S, Fukasawa T, Chong JM, et al. C-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal). Jpn J Cancer Res. 1999;90:1321-1328.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 1321-1328
-
-
Sakurai, S.1
Fukasawa, T.2
Chong, J.M.3
-
28
-
-
0032950650
-
Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of Cajal
-
Sakurai S, Fukasawa T, Chong JM, et al. Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of Cajal. Am J Pathol. 1999;154:23-28.
-
(1999)
Am J Pathol
, vol.154
, pp. 23-28
-
-
Sakurai, S.1
Fukasawa, T.2
Chong, J.M.3
-
29
-
-
0034889848
-
Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum
-
Sakurai S, Hishima T, Takazawa Y, et al. Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum. Pathol Int. 2001; 51:524-531.
-
(2001)
Pathol Int
, vol.51
, pp. 524-531
-
-
Sakurai, S.1
Hishima, T.2
Takazawa, Y.3
-
30
-
-
0034981645
-
Mutations in c-kit gene exons 9 and 13 in gastrointestinal stromal tumors among Japanese
-
Sakurai S, Oguni S, Hironaka M, et al. Mutations in c-kit gene exons 9 and 13 in gastrointestinal stromal tumors among Japanese. Jpn J Cancer Res. 2001;92:494-498.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 494-498
-
-
Sakurai, S.1
Oguni, S.2
Hironaka, M.3
-
31
-
-
0033199890
-
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors
-
Taniguchi M, Nishida T, Hirota S, et al. Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors. Cancer Res. 1999;59:4297-4300.
-
(1999)
Cancer Res
, vol.59
, pp. 4297-4300
-
-
Taniguchi, M.1
Nishida, T.2
Hirota, S.3
-
32
-
-
0035899418
-
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
-
Tuveson DA, Willis NA, Jacks T, et al. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. Oncogene. 2001;20:5054-5058.
-
(2001)
Oncogene
, vol.20
, pp. 5054-5058
-
-
Tuveson, D.A.1
Willis, N.A.2
Jacks, T.3
-
33
-
-
0036769721
-
Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: A report of the EORTC Soft Tissue and Bone Sarcoma Group
-
Van Oosterom AT, Judson IR, Verweij J, et al. Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: a report of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer. 2002;38(suppl 5):83-87.
-
(2002)
Eur J Cancer
, vol.38
, Issue.SUPPL. 5
, pp. 83-87
-
-
Van Oosterom, A.T.1
Judson, I.R.2
Verweij, J.3
-
34
-
-
0036175997
-
c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant
-
Wardelmann E, Neidt I, Bierhoff E, et al. c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant. Mod Pathol. 2002;15:125-136.
-
(2002)
Mod Pathol
, vol.15
, pp. 125-136
-
-
Wardelmann, E.1
Neidt, I.2
Bierhoff, E.3
-
35
-
-
0037854680
-
p53 mutation and MDM2 amplification in inflammatory myofibroblastic tumours
-
Yamamoto H, Oda Y, Saito T, et al. p53 mutation and MDM2 amplification in inflammatory myofibroblastic tumours. Histopathology. 2003;42: 431-439.
-
(2003)
Histopathology
, vol.42
, pp. 431-439
-
-
Yamamoto, H.1
Oda, Y.2
Saito, T.3
|