C-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant

Modern Pathology

Volumn 15, Issue 2, 2002, Pages 125-136

  Wardelmann, Eva ^a   Neidt, Iris ^a   Bierhoff, Erhard ^b   Speidel, Nicola ^a   Manegold, Christoph ^c   Fischer, Hans Peter ^a   Pfeifer, Ulrich ^a   Pietsch, Torsten ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b Institute of Pathology and Neuropathology   (Germany)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

c kit; Gastrointestinal stromal tumor; Gastrointestinal tract; Immunohistochemistry; KIT mutation; Mesenchymal tumor; Phenotype

Indexed keywords

CD34 ANTIGEN; DNA; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; EPITHELIOID CELL; FEMALE; GASTROINTESTINAL TUMOR; GENE EXPRESSION; GENE MUTATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; MESENCHYME; MUTATION RATE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTO ONCOGENE; SINGLE STRAND CONFORMATION POLYMORPHISM; SPINDLE CELL; STROMA;

AGED; AMINO ACID SEQUENCE; ANTIGENS, CD34; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; EPITHELIOID CELLS; FEMALE; GASTROINTESTINAL NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; MUTATION, MISSENSE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-KIT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; VIMENTIN;

EID: 0036175997     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880504     Document Type: Article

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