Functional characterization of the common amino acid 897 polymorphism of the cardiac potassium channel KCNH2 (HERG)

Cardiovascular Research

Volumn 59, Issue 3, 2003, Pages 603-611

  Paavonen, Kristian J ^a,b   Chapman, Hugh ^a   Laitinen, Päivi J ^b   Fodstad, Heidi ^b   Piippo, Kirsi ^b   Swan, Heikki ^b   Toivonen, Lauri ^b   Viitasalo, Matti ^b   Kontula, Kimmo ^b   Pasternack, Michael ^a,c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c ORION CORPORATION   (Finland)

Author keywords

Arrhythmia; ECG; K channel; Long QT syndrome; Membrane currents

Indexed keywords

AMINO ACID; LYSINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNQ1; THREONINE;

ADOLESCENT; ADULT; AGED; ALLELE; ANIMAL CELL; ARTICLE; CHILD; CONTROLLED STUDY; DENSITY; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; EMBRYO; EXERCISE TEST; FEMALE; GENE EXPRESSION; GENE MUTATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; LONG QT SYNDROME; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POTASSIUM CHANNEL KCNH2; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; QT PROLONGATION; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANIMALS; CATION TRANSPORT PROTEINS; CELL LINE; CHILD; CHILD, PRESCHOOL; COS CELLS; DNA-BINDING PROTEINS; ELECTROCARDIOGRAPHY; ETHER-A-GO-GO POTASSIUM CHANNELS; EXERCISE TEST; FEMALE; GENE EXPRESSION; HETEROZYGOTE; HUMANS; KIDNEY; LONG QT SYNDROME; MALE; MIDDLE AGED; PATCH-CLAMP TECHNIQUES; POLYMORPHISM, GENETIC; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TRANS-ACTIVATORS; TRANSFECTION;

EID: 12144288231     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00458-9     Document Type: Article

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