Genetic and molecular basis of cardiac arrhythmias: Impact on clinical management part III

Circulation

Volumn 99, Issue 5, 1999, Pages 674-681

  Priori, Silvia G ^a   Barhanin, Jacques ^b   Hauer, Richard N W ^j   Haverkamp, Wilhelm ^j   Jongsma, Habo J ^j   Kleber, André G ^j   McKenna, William J ^c   Roden, Dan M ^d   Rudy, Yoram ^e   Schwartz, Ketty ^f   Schwartz, Peter J ^g   Towbin, Jeffrey A ^h   Wilde, Arthur M ⁱ  

^a IRCCS   (Italy)

^b CNRS   (France)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Case Western Reserve University   (United States)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^h TEXAS CHILDREN S HOSPITAL   (United States)

ⁱ ACADEMIC MEDICAL CENTER   (Netherlands)

^j NONE

more..

Author keywords

Arrhythmia; Death, sudden; Genetics; Molecular biology electrophysiology

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL;

ARTICLE; CELL INTERACTION; CYTOPATHOLOGY; ELECTROCARDIOGRAM; GENE DISRUPTION; GENE EXPRESSION; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; HUMAN; ION CURRENT; NONHUMAN; PRIORITY JOURNAL;

EID: 0033537474     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.5.674     Document Type: Article

References (68)

1. Note, References 1 through 94 appear in Parts I and II of this article, published in Circulation. 1999;99:518-528 (February 2 issue).
2. Noda M, Shimizu S, Tanabe T, Takai T, Kayano T, Ikeda T, Takahashi H, Nakayama H, Kanaoka Y, Minamino N, Kangawa K, Matsuo H, Raftery MA, Hirose T, Inayama S, Hayashida H, Miyata T, Numa S. Primary structure of Electrophones electricus sodium channel deduced from cDNA sequence. Nature. 1984;312:121-127.
3. Deal KK, England SK, Tamkun MM. Molecular physiology of cardiac potassium channels. Physiol Rev. 1996;76:49-67.
4. Hosey MM, Chien AJ, Puri TS. Structure and regulation of L-type calcium channels: a current assessment of the properties and roles of channel subunits. Trends Cardiovasc Med. 1996;6:265-273.
5. Roden DM, George A Jr. Structure and function of cardiac sodium and potassium channels. Am J Physiol. 1997;273:H511-H525.
6. Isom LL, Dejongh KS, Catterall WA. Auxiliary subunits of voltage-gated ion channels. Neuron. 1994;12:1183-1194.
7. Adelman JP. Proteins that interact with the pore-forming subunits of voltage-gated ion channels. Curr Opin Neurobiol. 1995;5:286-295.
8. + channels involved in mediating protein-protein interactions. Biochem Biophys Res Commun. 1997;232:585-589.
9. Kr potassium channel. Cell 1995;81:299-307.
10. Kr. Nature. 1997;388:289-292.
11. + current. Circ Res. 1995;77:1246-1253.
12. + channel in ventricular muscle: a molecular correlate for the transient outward current. Circ Res. 1996; 79:659-668.
13. Tyson J, Tranebjærg L, Bellman S, Wren C, Taylor J, Bathen J, Aslaksen B, Sørland SJ, Lund O, Malcolm S, Pembrey M, Bhattacharya S, Bitner-Glindzicz M. IsK and KvLQT1: mutation in either of the two subunits of the slow component of the delayed rectifier potassium channel can cause Jervell and Lange-Nielsen syndrome. Hum Mol Genet. 1997;6:2179-2185.
14. Vetter DE, Mann JR, Wangemann P, Liu JZ, McLaughlin KJ, Lesage F, Marcus DC, Lazdunski M, Heinemann SF, Barhanin J. Inner ear defects induced by null mutation of the IsK gene. Neuron. 1996;17:1251-1264.
15. + channels in mouse heart. Circ Res. 1996;79:79-85.
16. Davies MP, An RH, Doevendans P, Kubalak S, Chien KR, Kass RS. Developmental changes in ionic channel activity in the embryonic murine heart. Circ Res. 1996;78:15-25.
17. Lipka LJ, Siegelbaum SA, Robinson RB, Berman MF. An analogue of cAMP mimics developmental change in neonatal rat ventricular myocyte sodium current kinetics. Am J Physiol. 1996;270:H194-H199.
18. Zhang JF, Robinson RB, Siegelbaum SA. Sympathetic neurons mediate developmental change in cardiac sodium channel gating through long-term neurotransmitter action. Neuron. 1992;9:97-103.
19. Yang T, Roden DM. Regulation of sodium current development in cultured atrial tumor myocytes (AT-1 cells). Am J Physiol. 1996;271: H541-H547.
20. Kupershmidt S, Yang T, Roden DM. Inhibition of β-subunit expression prevents development of mature sodium current phenotype in cultured heart cells. Circulation. 1996;94(suppl I):I-287. Abstract.
21. Malfatto G, Rosen TS, Steinberg SF, Ursell PC, Sun LS, Daniel S, Danilo PJ, Rosen MR. Sympathetic neural modulation of cardiac impulse initiation and repolarization in the newborn rat. Circ Res. 1990;66:427-437.
22. Zipes DP. Influence of myocardial ischemia and infarction on autonomic innervation of heart. Circulation. 1990;82:1095-1105.
23. Abrahamsson C, Palmer M, Ljung B, Duker G, Baarnhielm C, Carlsson L, Danielsson B. Induction of rhythm abnormalities in the fetal rat heart: a tentative mechanism for the embryotoxic effect of the class III antiarrhythmic agent almokalant. Cardiovasc Res. 1994;28:337-344.
24. Delorme B, Dahl E, Jarry GT, Marics I, Briand JP, Willecke K, Gros D, Theveniau RM. Developmental regulation of connexin 40 gene expression in mouse heart correlates with the differentiation of the conduction system. Dev Dyn. 1995;204:358-371.
25. Delorme B, Dahl E, Jarry GT, Briand JP, Willecke K, Gros D, Theveniau RM. Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system. Circ Res. 1997;81:423-437.
26. Wang Z, Fermini B, Nattel S. Delayed rectifier outward current and repolarization in human atrial myocytes. Circ Res. 1993;73:276-285.
27. + channel mRNA in isolated ferret cardiac myocytes. Circ Res. 1996;78: 1083-1089.
28. Kupershmidt S, Sutherland M, King D, Magnuson MA. Roden DM. Replacement by homologous recombination of the minK gene with LacZ reveals cell-specific minK expression. Biophys J. 1997;72:A226. Abstract.
29. Antzelevitch C, Sicouri S, Litovsky SH, Lukas A, Krishnan SC, Di DJ, Gintant GA, Liu DW. Heterogeneity within the ventricular wall: electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ Res. 1991;69:1427-1449.
30. Strauss HC, Bigger JJ, Hoffman BF. Electrophysiological and β-receptor blocking effects of MJ 1999 on dog and rabbit cardiac tissue. Circ Res. 1970;26:661-678.
31. Roden DM, Hoffman BF. Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers: relationship to potassium and cycle length. Circ Res. 1985;56:857-867.
32. Ks contributes to the longer action potential of the M cell. Circ Res. 1995;76:351-365.
33. Dixon JE, McKinnon D. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ Res. 1994;75:252-260.
34. Näbauer M, Beuckelmann DJ, Uberfuhr P, Steinbeck G. Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation. 1996;93:168-177.
35. Po S, Roberds S, Snyders DJ, Tamkun MM, Bennett PB. Heteromultimeric assembly of human potassium channels: molecular basis of a transient outward current? Circ Res. 1993;72:1326-1336.
36. Gros DB, Jongsma HJ. Connexins in mammalian heart function. Bioessays. 1996;18:719-730.
37. Anumonwo JM, Wang HZ, Trabka JE, Dunham B, Veenstra RD, Delmar M, Jalife J. Gap junctional channels in adult mammalian sinus nodal cells: immunolocalization and electrophysiology. Circ Res. 1992;71:229-239.
38. Trabka JE, Coombs W, Lemanski LF, Delmar M, Jalife J. Immunohistochemical localization of gap junction protein channels in hamster sinoatrial node in correlation with electrophysiologic mapping of the pacemaker region. J Cardiovasc Electrophysiol. 1994;5:125-137.
39. ten Velde I, de Jonge B, Verheijck EE, van Kempen MJ, Analbers L, Gros D, Jongsma HJ. Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium. Circ Res. 1995;76:802-811.
40. Guerrero PA, Schuessler RB, Davis LM, Beyer EC, Johnson CM, Yamada KA, Saffitz JE. Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J Clin Invest. 1997;99:1991-1998.
41. Kanter HL, Laing JG, Beau SL, Beyer EC, Saffitz JE. Distinct patterns of connexin expression in canine Purkinje fibers and ventricular muscle. Circ Res. 1993;72:1124-1131.
42. Luo CH, Rudy Y. A dynamic model of the cardiac ventricular action potential, I: simulations of ionic currents and concentration changes. Circ Res. 1994;74:1071-1096.
43. Fabiato A. Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol. 1985;85:291-320.
44. Yue DT, Backx PH, Imredy JP. Calcium-sensitive inactivation in the gating of single calcium channels. Science. 1990;250:1735-1738.
45. 2+ release from sarcoplasmic reticulum in guinea pig ventricular myocytes. Circ Res. 1995;76:102-109.
46. 2+ influx during the cardiac action potential in guinea pig ventricular myocytes. Circ Res. 1996;79: 194-200.
47. Zeng J, Rudy Y. Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J. 1995;68:949-964.
48. 2+ current. Circ Res. 1989;64: 977-990.
49. Janse MJ, van der Steen A, van Dam R. Refractory period of the dog's ventricular myocardium following sudden changes in frequency. Circ Res. 1969;24:251-262.
50. Jack JJB, Noble D, Tsien RW. Electric Current Flow in Excitable Cells. Oxford, UK: Clarendon Press; 1975.
51. Buchanan JW, Saito T, Gettes LS. The effects of antiarrhythmic drugs, stimulation frequency, and potassium-induced resting membrane potential changes on conduction velocity and dV/dtmax in guinea pig myocardium. Circ Res. 1985;56:696-703.
52. Kleber AG, Riegger CB, Janse MJ. Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle. Circ Res. 1987;61:271-279.
53. Riegger CB, Alperovich G, Kleber AG. Effect of oxygen withdrawal on active and passive electrical properties of arterially perfused rabbit ventricular muscle. Circ Res. 1989;64:532-541.
54. Rudy Y, Quan W. A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue. Circ Res. 1987;61: 815-823.
55. Peters NS. New insights into myocardial arrhythmogenesis: distribution of gap-junctional coupling in normal, ischemic and hypertrophied human hearts. Clin Sci. 1996;90:447-452.
56. Shaw RM, Rudy Y. Ionic mechanisms of propagation in cardiac tissue: roles of sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ Res. 1997;81:727-741.
57. Joyner RW, Kumar R, Wilders R, Jongsma HJ, Verheijck EE, Golod DA, Van GA, Wagner MB, Goolsby WN. Modulating L-type calcium current affects discontinuous cardiac action potential conduction. Biophys J. 1996;71:237-245.
58. Weidmann S. Effect of current flow on cardiac muscle. J Physiol (Lond). 1951;115:227-236.
59. Le Grice IJ, Smaill BH, Chai LZ, Edgar SG, Gavin JB, Hunter PJ. Laminar structure of the heart: ventricular myocyte arrangement and connective tissue architecture in the dog. Am J Physiol. 1995;38: H571-H582.
60. Spach MS, Josephson ME. Initiating reentry: the role of nonuniform anisotropy in small circuits. J Cardiovasc Electrophysiol. 1994;5: 182-209.
61. Cabo C, Pertsov AM, Baxter WT, Davidenko JM, Gray RA, Jalife J. Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle. Circ Res. 1994;75:1014-1028.
62. Fast VG, Kléber AG. Role of wavefront curvature in propagation of cardiac impulse. Cardiovasc Res. 1996;33:258-271.
63. Fast VG, Kleber AG. Cardiac tissue geometry as a determinant of unidirectional conduction block: assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model. Cardiovasc Res. 1995;29:697-707.
64. Rohr S, Salzberg BM. Characterization of impulse propagation at the microscopic level across geometrically defined expansions of excitable tissue: multiple site optical recording of transmembrane voltage (MSORTV) in patterned growth heart cell cultures. J Gen Physiol. 1994;104:287-309.
65. Spach MS, Kootsey JM. Relating the sodium current and conductance to the shape of transmembrane and extracellular potentials by simulation: effects of propagation boundaries. IEEE Trans Biomed Eng. 1985;32: 743-755.
66. Iida M, Kodama I, Toyama J. Negative dromotropic effects of class I antiarrhythmic drugs in anisotropic ventricular muscle. Cardiovasc Res. 1996;31:640-650.
67. Rohr S, Kucera J. Involvement of the calcium inward current in cardiac impulse propagation: induction of unidirection conduction block by nifedipine and reversal by K 8644. Biophys J. 1996;72:745-766.
68. Rohr S, Kucera JP, Fast VG, Kléber AG. Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncoupling. Science. 1997;275:841-844.