메뉴 건너뛰기




Volumn 18, Issue 5, 1996, Pages 371-378

Molecular mechanisms of anti-inflammatory action of glucocorticoids

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CELL ADHESION MOLECULE; CYTOKINE; ENZYME; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

EID: 0030138947     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950180507     Document Type: Article
Times cited : (302)

References (67)
  • 1
    • 0025015647 scopus 로고
    • Antitumor promotion and anti-inflammation: Downmodulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
    • Jonat, C. et al. (1990). Antitumor promotion and anti-inflammation: downmodulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62, 1189-1204.
    • (1990) Cell , vol.62 , pp. 1189-1204
    • Jonat, C.1
  • 2
    • 0025188132 scopus 로고
    • Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DMA binding due to direct proteinprotein interaction
    • Yang-Yen, H.-F. et al. (1990). Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DMA binding due to direct proteinprotein interaction. Cell 62, 1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.-F.1
  • 3
    • 0025081214 scopus 로고
    • Transcription factor interactions: Selectors of positive or negative regulation from a single DMA element
    • Diamond, M. I., Miner, J. N., Yoshinaga, S. K. and Yamamoto, K. R. (1990) Transcription factor interactions: selectors of positive or negative regulation from a single DMA element. Science 249, 1266-1272.
    • (1990) Science , vol.249 , pp. 1266-1272
    • Diamond, M.I.1    Miner, J.N.2    Yoshinaga, S.K.3    Yamamoto, K.R.4
  • 4
    • 0025130179 scopus 로고
    • Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
    • Schüle, B. et al. (1990). Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62, 1217-1226.
    • (1990) Cell , vol.62 , pp. 1217-1226
    • Schüle, B.1
  • 5
    • 0025150272 scopus 로고
    • Mutual transrepression of Fos and the glucocorticoid receptor: Involvement of a functional domain in Fos which is absent in Fos B
    • Lucibello, F. C., Slater, E. P., Jooss, K. U., Beato, M. and Müller, R. (1990). Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in Fos B. EMBO J. 9, 2827-2834.
    • (1990) EMBO J. , vol.9 , pp. 2827-2834
    • Lucibello, F.C.1    Slater, E.P.2    Jooss, K.U.3    Beato, M.4    Müller, R.5
  • 6
    • 0027058940 scopus 로고
    • The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element
    • Miner, J. N. and Yamamoto, K. R. (1992). The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element. Genes Dev. 6, 2491-2501.
    • (1992) Genes Dev. , vol.6 , pp. 2491-2501
    • Miner, J.N.1    Yamamoto, K.R.2
  • 7
    • 0029032699 scopus 로고
    • The glucocorticoid receptor synergizes with Jun homodimers to activate AP-1-regulated promoters lacking GR binding sites
    • Teurich, S. and Angel, P. (1995). The glucocorticoid receptor synergizes with Jun homodimers to activate AP-1-regulated promoters lacking GR binding sites. Chemical Senses 20, 251 -255.
    • (1995) Chemical Senses , vol.20 , pp. 251-255
    • Teurich, S.1    Angel, P.2
  • 8
    • 0028157769 scopus 로고
    • Involvement of c-Jun in the control of glucocorticoid receptor transcriptional activity during development of chicken retinal tissue
    • Berko-Flint, Y., Levkowitz, G. and Vardimon, L. (1994). Involvement of c-Jun in the control of glucocorticoid receptor transcriptional activity during development of chicken retinal tissue. EMBO J. 13, 646-654.
    • (1994) EMBO J. , vol.13 , pp. 646-654
    • Berko-Flint, Y.1    Levkowitz, G.2    Vardimon, L.3
  • 9
    • 0027992051 scopus 로고
    • 12-O-tetradecanoylphorbol-13-acetate- And tumor necrosis factor α-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone
    • Van de Stolpe, A. et al. (1994). 12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor α-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. J. Biol. Chem. 269, 6185-6192.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6185-6192
    • Van De Stolpe, A.1
  • 10
    • 0000693107 scopus 로고
    • Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA
    • Lee, S. W. et al. (1988). Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA. Proc. Natl Acad. Sci. USA. 85, 1204-1208.
    • (1988) Proc. Natl Acad. Sci. USA. , vol.85 , pp. 1204-1208
    • Lee, S.W.1
  • 11
    • 0028305712 scopus 로고
    • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression
    • Mukalda, N. et al. (1994). Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression. J. Biol. Chem. 269, 13289-13295.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13289-13295
    • Mukalda, N.1
  • 12
    • 0027494730 scopus 로고
    • Anti-inflammatory action of steroids: Molecular mechanisms
    • Barnes, J. P. and Adeock, I. (1993). Anti-inflammatory action of steroids: molecular mechanisms. Trends Pharmacol. Sci. 14, 436-441.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 436-441
    • Barnes, J.P.1    Adeock, I.2
  • 13
    • 0026543409 scopus 로고
    • Interference of pathway specific transcription factors
    • Ponta, H., Cato, A. C. B. and Herrlich, P. (1992). Interference of pathway specific transcription factors. Biochim. Biophys. Acta. 1129, 255-261.
    • (1992) Biochim. Biophys. Acta. , vol.1129 , pp. 255-261
    • Ponta, H.1    Cato, A.C.B.2    Herrlich, P.3
  • 14
    • 0026236698 scopus 로고
    • Joints in the regulatory lattice: Composite regulation by steroid receptor-AP-1 complexes
    • Miner, J. N., Diamond, M. I. and Yamamoto, K. R. (1991). Joints in the regulatory lattice: composite regulation by steroid receptor-AP-1 complexes. Cell Growth Differ. 2, 525-530.
    • (1991) Cell Growth Differ. , vol.2 , pp. 525-530
    • Miner, J.N.1    Diamond, M.I.2    Yamamoto, K.R.3
  • 15
    • 0025804498 scopus 로고
    • The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter, a potential mechanism of negative regulation
    • Strömstedt, P.-E., Poellinger, L., Gustafsson, J.-Å. and Carlstedt.-Duke, J. (1991). The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter, a potential mechanism of negative regulation. Mol. Cell Biol. 11, 3379-3383.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3379-3383
    • Strömstedt, P.-E.1    Poellinger, L.2    Gustafsson, J.-Å.3    Carlstedt-Duke, J.4
  • 16
    • 0024080921 scopus 로고
    • Hormone-mediated repression: A negative glucocorticoid response element from the bovine prolactin gene
    • Sakai, D. D. et al. (1988). Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes Dev. 2, 1144-1154.
    • (1988) Genes Dev. , vol.2 , pp. 1144-1154
    • Sakai, D.D.1
  • 17
    • 0027752819 scopus 로고
    • Inhibition of gene expression by steroid hormone receptors via a negative glucocorticoid response element: Evidence for the involvement of DNA-binding and agonistic effects of the antiglucocorticoid/antiprogestin RU486
    • Cairns, C., Cairns, W. and Okret, S. (1993). Inhibition of gene expression by steroid hormone receptors via a negative glucocorticoid response element: evidence for the involvement of DNA-binding and agonistic effects of the antiglucocorticoid/antiprogestin RU486. DNA 12, 695-702.
    • (1993) DNA , vol.12 , pp. 695-702
    • Cairns, C.1    Cairns, W.2    Okret, S.3
  • 18
    • 0024744568 scopus 로고
    • Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities
    • Schena, M., Freedman, L. P. and Yamamoto, K. (1989) Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. Genes Dev. 3, 1590-1601.
    • (1989) Genes Dev. , vol.3 , pp. 1590-1601
    • Schena, M.1    Freedman, L.P.2    Yamamoto, K.3
  • 19
    • 0022385983 scopus 로고
    • Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells
    • Campar, S. A., Yao, Y. A. S. and Rottman, F. M. (1985). Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells. J. Biol. Chem. 260, 12246-12251.
    • (1985) J. Biol. Chem. , vol.260 , pp. 12246-12251
    • Campar, S.A.1    Yao, Y.A.S.2    Rottman, F.M.3
  • 20
    • 0021134898 scopus 로고
    • Characterization of the bovine prolactin gene
    • Campar, S. A. et al. (1984). Characterization of the bovine prolactin gene. DNA 3, 237-249.
    • (1984) DNA , vol.3 , pp. 237-249
    • Campar, S.A.1
  • 21
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
    • Ray, A. and Prefontaine, K. E. (1994). Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl Acad. Sci. USA 91, 752-756.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 22
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kB by activated glucocorticoid receptors
    • Scheinman, R. I., Gualberto, A., Jewell, C. M., Cidlowski, J. A. and Baldwin, A. S. Jr. (1995). Characterization of mechanisms involved in transrepression of NF-kB by activated glucocorticoid receptors. Mol. Cell. Biol. 15, 943-953.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin Jr., A.S.5
  • 23
    • 0026579203 scopus 로고
    • Interference between pathway-specific transcription factors: Glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo
    • König, H., Ponta, H., Rahmsdorf, H. J. and Herrlich, P. (1992). Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J.11, 2241-2246.
    • (1992) EMBO J. , vol.11 , pp. 2241-2246
    • König, H.1    Ponta, H.2    Rahmsdorf, H.J.3    Herrlich, P.4
  • 24
    • 0024388773 scopus 로고
    • Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription
    • Drouin, J., Trifiro, M. A., Plante, R. K., Nemer, M., Eriksson, P. and Wrange, Ö. (1989). Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol. Cell. Biol. 9, 5305-5314.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 5305-5314
    • Drouin, J.1    Trifiro, M.A.2    Plante, R.K.3    Nemer, M.4    Eriksson, P.5    Wrange, Ö.6
  • 25
    • 0027402820 scopus 로고
    • Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene
    • Drouin, J. et al. (1993). Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12, 145-156.
    • (1993) EMBO J. , vol.12 , pp. 145-156
    • Drouin, J.1
  • 26
    • 0026408605 scopus 로고
    • Pro-opiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription
    • Riegel, A. T., Lu, Y., Remenick, J., Wolford, R. G., Berard, D. S. and Hager, G. L. (1991) Pro-opiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription. Mol. Endocrinol. 5, 1973-1982.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1973-1982
    • Riegel, A.T.1    Lu, Y.2    Remenick, J.3    Wolford, R.G.4    Berard, D.S.5    Hager, G.L.6
  • 27
    • 0025827416 scopus 로고
    • Characterization of functional inhibition of the glucocorticoid receptor by Fos/Jun
    • Tourray, M., Ryan, F., Jaggi, R. and Martin, F. (1991) Characterization of functional inhibition of the glucocorticoid receptor by Fos/Jun. Oncogene 6, 1227-1234.
    • (1991) Oncogene , vol.6 , pp. 1227-1234
    • Tourray, M.1    Ryan, F.2    Jaggi, R.3    Martin, F.4
  • 28
    • 0027415164 scopus 로고
    • Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids
    • Imai, E., Miner, J. N., Mitchell, J. A., Yamamoto, K. R. and Granner, D. K. (1993). Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. J. Biol. Chem. 268, 5353-5356.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5353-5356
    • Imai, E.1    Miner, J.N.2    Mitchell, J.A.3    Yamamoto, K.R.4    Granner, D.K.5
  • 29
    • 0026686619 scopus 로고
    • Functional interference between the ubiquitous and constitutive octamer transcription factor 1 (OTF-1 ) and the glucocorticoid receptor by protein-protein interaction involving the homeo subdomain of OTF-1
    • Kutoh, E., Strömstedt, P.-E. and Poellinger, L. (1992). Functional interference between the ubiquitous and constitutive octamer transcription factor 1 (OTF-1 ) and the glucocorticoid receptor by protein-protein interaction involving the homeo subdomain of OTF-1. Mol. Cell. Biol. 12, 4960-4969.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4960-4969
    • Kutoh, E.1    Strömstedt, P.-E.2    Poellinger, L.3
  • 30
    • 0026857927 scopus 로고
    • Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells
    • Stauber, C., Altschmied, J., Akerblom, I., Marron, J. L. and Mellon, P. L. (1992). Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells. The New Biologist 4, 527-540.
    • (1992) The New Biologist , vol.4 , pp. 527-540
    • Stauber, C.1    Altschmied, J.2    Akerblom, I.3    Marron, J.L.4    Mellon, P.L.5
  • 31
    • 0025912991 scopus 로고
    • Regulation of α-fetoprotein gene expression by antagonism between AP-1 and the glucocorticoid receptor at their overlapping site
    • Zhang, X.-K., Dong, J.-M. and Chiu, J.-F. (1991). Regulation of α-fetoprotein gene expression by antagonism between AP-1 and the glucocorticoid receptor at their overlapping site. J. Biol. Chem. 266, 8248-8254.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8248-8254
    • Zhang, X.-K.1    Dong, J.-M.2    Chiu, J.-F.3
  • 32
    • 0026507209 scopus 로고
    • Glucocorticoid receptor-mediated suppression of the interieukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements
    • Vacca, A. et al. (1992). Glucocorticoid receptor-mediated suppression of the interieukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements. J. Exp. Med. 175, 637-646.
    • (1992) J. Exp. Med. , vol.175 , pp. 637-646
    • Vacca, A.1
  • 33
    • 0027491776 scopus 로고
    • The T-cell transcription factor NF-ATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J. et al. (1993). The T-cell transcription factor NF-ATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365, 352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1
  • 34
    • 0027394555 scopus 로고
    • Mineralocorticoid and glucocorticoid receptor activities distinguished by non-receptor factors at a composite response element
    • Pearce, D. and Yamamoto, K. R. (1993). Mineralocorticoid and glucocorticoid receptor activities distinguished by non-receptor factors at a composite response element. Science 259, 1161-1165.
    • (1993) Science , vol.259 , pp. 1161-1165
    • Pearce, D.1    Yamamoto, K.R.2
  • 35
    • 0027269689 scopus 로고
    • Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro
    • Kerppola, T. K., Luk, D. and Curran, T. (1993). Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro. Mol. Cell. Biol. 13, 3782-3791.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3782-3791
    • Kerppola, T.K.1    Luk, D.2    Curran, T.3
  • 36
    • 0027934108 scopus 로고
    • A distinct modulating domain in glucocorticoid receptor monomers in repression of activity of the transcription factor AP-1
    • Heck, S. et al. (1994). A distinct modulating domain in glucocorticoid receptor monomers in repression of activity of the transcription factor AP-1. EMBO J. 13, 4087-4095.
    • (1994) EMBO J. , vol.13 , pp. 4087-4095
    • Heck, S.1
  • 37
    • 0000044133 scopus 로고
    • Inflammatory reaction in arthritis
    • ed. E. Davis and J. Dingle Academic Press Ltd, London
    • Fassbender, H. G. (1994) Inflammatory reaction in arthritis. In Immunopharmocology of Joints and Connective Tissues (ed. E. Davis and J. Dingle), pp. 165-198. Academic Press Ltd, London.
    • (1994) Immunopharmocology of Joints and Connective Tissues , pp. 165-198
    • Fassbender, H.G.1
  • 38
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reaction and inflammation
    • Samuelsson, B. (1988). Leukotrienes: mediators of immediate hypersensitivity reaction and inflammation. Science 220, 568-575.
    • (1988) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 39
    • 0027982876 scopus 로고
    • Traffic signals for lymphocytes recirculation and leukocyte emigration. the multiple paradigm
    • Springer, T. A. (1994). Traffic signals for lymphocytes recirculation and leukocyte emigration. The multiple paradigm. Cell 76, 301-314.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 40
    • 0023488843 scopus 로고
    • Identification of an inducible endothelialleukocyte adhesion molecule
    • Bevilacqua, M. P. et al. (1987). Identification of an inducible endothelialleukocyte adhesion molecule. Proc. Natl Acad. Sci. USA 84, 9238-9242.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 9238-9242
    • Bevilacqua, M.P.1
  • 41
    • 0027742762 scopus 로고
    • Cytokines and the acute phase response in SLE
    • Gordon, C. and Emery, P. (1993). Cytokines and the acute phase response in SLE. Lupus 2, 345-347.
    • (1993) Lupus , vol.2 , pp. 345-347
    • Gordon, C.1    Emery, P.2
  • 42
    • 0026470092 scopus 로고
    • A mechanism for the anti-inflammatory effects of corticosterone: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1
    • Cronstein, B. N., Kimmel, S. C., Levin, R. I., Martiniuk, F. and Weissmann, G. (1992) A mechanism for the anti-inflammatory effects of corticosterone: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc. Natl Acad. Sci. USA 89, 9991-9995.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 9991-9995
    • Cronstein, B.N.1    Kimmel, S.C.2    Levin, R.I.3    Martiniuk, F.4    Weissmann, G.5
  • 43
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • Flower, R. J. and Rothwell, N. J. (1994). Lipocortin-1: cellular mechanisms and clinical relevance. Trends Pharmacol. Sci. 15, 71-76.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 44
    • 0023198120 scopus 로고
    • Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung
    • Cirino, G., Flower, R. J., Browning, J. L., Sinclair, K. L. and Pepinsky, R. B. (1987). Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung. Nature 328, 270-272.
    • (1987) Nature , vol.328 , pp. 270-272
    • Cirino, G.1    Flower, R.J.2    Browning, J.L.3    Sinclair, K.L.4    Pepinsky, R.B.5
  • 45
    • 0027942832 scopus 로고
    • Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: Regulation by dexamethasone
    • Mitchell, A. J. et al. (1994). Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br. J. Pharmacol. 113, 1008-1014.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 1008-1014
    • Mitchell, A.J.1
  • 46
    • 0025672648 scopus 로고
    • Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
    • Radomski, N. W., Palmer, R. M. J. and Moncada, S. (1990). Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc. Natl Acad. Sci. USA 87, 10043-10047.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 10043-10047
    • Radomski, N.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 47
    • 0028897431 scopus 로고
    • Nitric oxide and asthmatic inflammation
    • Barnes, R. J. and Liew, F. Y. (1995). Nitric oxide and asthmatic inflammation. Immunology Today 16, 128-130.
    • (1995) Immunology Today , vol.16 , pp. 128-130
    • Barnes, R.J.1    Liew, F.Y.2
  • 48
    • 0028999596 scopus 로고
    • Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
    • MacMicking, J. D.et al. (1995). Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81, 641-650.
    • (1995) Cell , vol.81 , pp. 641-650
    • MacMicking, J.D.1
  • 49
    • 0029035476 scopus 로고
    • Altered immune responses in mice lacking inducible nitric oxide synthase
    • Wei, X.Q. et al. (1995). Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375, 408-411.
    • (1995) Nature , vol.375 , pp. 408-411
    • Wei, X.Q.1
  • 50
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R. I., Cogswell, P. C., Lofquist, A. K. and Baldwin Jr., A. S. (1995). Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270, 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 51
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan, N., Didonato, J. A., Rosette, C., Helmberg, A. and Karin, M. (1995). Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270, 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 52
    • 0028211578 scopus 로고
    • Cross-talk modulations of signal transduction pathways: Two mechanisms are involved in the control of tyrosine aminotransferase gene expression by phorbol esters
    • Reik, A., Stewart, A. F. and Schütz, G. (1994). Cross-talk modulations of signal transduction pathways: two mechanisms are involved in the control of tyrosine aminotransferase gene expression by phorbol esters. Mol. Endocrinol. 8, 490-497.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 490-497
    • Reik, A.1    Stewart, A.F.2    Schütz, G.3
  • 53
    • 0027536972 scopus 로고
    • A nuclear factor for interteukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of rat α1-acid glycoprotein gene via direct protein-protein interaction
    • Nishio, Y., Isshiki, H., Kishimoto, T. and Akira, S. (1993). A nuclear factor for interteukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of rat α1-acid glycoprotein gene via direct protein-protein interaction. Mol. Cell. Biol. 13, 1854-1862.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1854-1862
    • Nishio, Y.1    Isshiki, H.2    Kishimoto, T.3    Akira, S.4
  • 54
    • 0025770260 scopus 로고
    • Repressor to activator switch by mutations in the first Zn finger of the glucocorticoid receptor: Is direct DMA binding necessary?
    • Ray, A., Leforge, K. S. and Sehgal, P. B. (1991). Repressor to activator switch by mutations in the first Zn finger of the glucocorticoid receptor: Is direct DMA binding necessary? Proc. Natl Acad. Sci. USA 188, 7086-7090.
    • (1991) Proc. Natl Acad. Sci. USA , vol.188 , pp. 7086-7090
    • Ray, A.1    Leforge, K.S.2    Sehgal, P.B.3
  • 55
    • 0029147741 scopus 로고
    • Repression of the interteukin-6 promoter by estrogen receptor is mediated by NF-κB and c/EBPβ
    • Stein, B. and Yang, M. X. (1995). Repression of the interteukin-6 promoter by estrogen receptor is mediated by NF-κB and c/EBPβ. Mol. Cell. Biol. 15, 4971-4979.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4971-4979
    • Stein, B.1    Yang, M.X.2
  • 56
    • 0028909667 scopus 로고
    • Negative cross-talk between RelA and the glucocorticoid receptor: A possible mechanism for the anti-inflammatory action of glucocorticoids
    • Caldenhoven, E. et al. (1995). Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the anti-inflammatory action of glucocorticoids. Mol. Endocrinol. 9, 401-412.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 401-412
    • Caldenhoven, E.1
  • 57
    • 0025948216 scopus 로고
    • Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription
    • Montgomery, K. F. et al. (1991). Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Proc. Natl Acad. Sci. USA 88, 6523-6527.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 6523-6527
    • Montgomery, K.F.1
  • 58
    • 0028300431 scopus 로고
    • NF-ATp: A transcription factor required for the co-ordinate induction of several cytokine genes
    • Rao, A. (1994). NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunology Today 15, 274-281.
    • (1994) Immunology Today , vol.15 , pp. 274-281
    • Rao, A.1
  • 59
    • 0027172987 scopus 로고
    • Negative transcriptional regulation of human Interleukin 2 (IL-2) gene by glucocorticoids through the interference of nuclear transcription factors AP-1 and NF-AT
    • Paliogianni, F., Raptis, A., Ahuja, S. S., Najjar, S. M. and Boumpas, D. T. (1993). Negative transcriptional regulation of human Interleukin 2 (IL-2) gene by glucocorticoids through the interference of nuclear transcription factors AP-1 and NF-AT. J. Clin. Invest. 91, 1481-1489.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1481-1489
    • Paliogianni, F.1    Raptis, A.2    Ahuja, S.S.3    Najjar, S.M.4    Boumpas, D.T.5
  • 60
    • 0028032457 scopus 로고
    • Transcription factors NF-IL6 and CREB recognize a common essential site in human prointerleukin 1 β gene
    • Tsukada, J., Saito, K., Waterman, W. R., Webb, A. C. and Auron, P. E. (1994). Transcription factors NF-IL6 and CREB recognize a common essential site in human prointerleukin 1 β gene. Mol. Cell. Biol. 14, 7285-7297.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7285-7297
    • Tsukada, J.1    Saito, K.2    Waterman, W.R.3    Webb, A.C.4    Auron, P.E.5
  • 61
    • 0000693107 scopus 로고
    • Glucocorticoids selectively inhibit the transcription of the interteukin 1β gene and decrease the stability of interleukin 1β mRNA
    • Lee, S. W. et al. (1988). Glucocorticoids selectively inhibit the transcription of the interteukin 1β gene and decrease the stability of interleukin 1β mRNA. Proc. Natl Acad. Sci. USA 485, 1204-1208.
    • (1988) Proc. Natl Acad. Sci. USA , vol.485 , pp. 1204-1208
    • Lee, S.W.1
  • 62
    • 0027939931 scopus 로고
    • Role of transcription factor NF-kB/Rel in induction of nitric oxide synthase
    • Xie, Q.-W., Kashiwabara, Y. and Nathan, C. (1994) Role of transcription factor NF-kB/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269, 4705-4708.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4705-4708
    • Xie, Q.-W.1    Kashiwabara, Y.2    Nathan, C.3
  • 63
    • 0027197860 scopus 로고
    • Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: Variable expression in various blistering diseases, induction during re-epithelialization and decrease by topical glucocorticoids
    • Oikarinen, A., Kylmäniemi, M., Autio-Harmainen, H., Antio, P. and Salo, T. (1993). Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: variable expression in various blistering diseases, induction during re-epithelialization and decrease by topical glucocorticoids. J. Invest. Dermatol. 101, 205-210.
    • (1993) J. Invest. Dermatol. , vol.101 , pp. 205-210
    • Oikarinen, A.1    Kylmäniemi, M.2    Autio-Harmainen, H.3    Antio, P.4    Salo, T.5
  • 65
    • 0027509817 scopus 로고
    • Repression of major histocompatibility complex IA expression by glucocorticoids: The glucocorticoid receptor inhibits the DNA binding of the X-box DNA binding protein
    • Celada, A., Mckercher, S. and Maki, R. A. (1993). Repression of major histocompatibility complex IA expression by glucocorticoids: the glucocorticoid receptor inhibits the DNA binding of the X-box DNA binding protein. J. Exp. Med. 177, 691-698.
    • (1993) J. Exp. Med. , vol.177 , pp. 691-698
    • Celada, A.1    Mckercher, S.2    Maki, R.A.3
  • 66
    • 5744251280 scopus 로고
    • Steroid hormone regulation of extracellular matrix proteins
    • ed. R. P. Mecham Academic Press, New York
    • Cutroneo, K. R., Sterling, Jr. K. M. and Shull, S. (1986). Steroid hormone regulation of extracellular matrix proteins. In Regulation of Matrix Accummulation (ed. R. P. Mecham), pp. 119-176. Academic Press, New York.
    • (1986) Regulation of Matrix Accummulation , pp. 119-176
    • Cutroneo, K.R.1    Sterling Jr., K.M.2    Shull, S.3
  • 67
    • 0028837242 scopus 로고
    • Glucocorticoid induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor
    • Helmberg, A., Auphan, N., Caelles, C. and Karin, M. (1995). Glucocorticoid induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. EMBO J. 14, 492-460.
    • (1995) EMBO J. , vol.14 , pp. 492-1460
    • Helmberg, A.1    Auphan, N.2    Caelles, C.3    Karin, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.