Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype

Developmental Biology

Volumn 278, Issue 1, 2005, Pages 155-162

  Aiyer, Aparna R ^a,b   Honarpour, Narimon ^a   Herz, Joachim ^a   Srivastava, Deepak ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Apaf 1; HAND2 null phenotype; Pharyngeal arches

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HAND2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA ARCH; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE INDUCTION; GROWTH DISORDER; HEART FAILURE; HYPOPLASIA; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALIA;

EID: 11844268660     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2004.11.001     Document Type: Article

References (37)

1. M. Abe, Y. Tamamura, H. Yamagishi, T. Maeda, J. Kato, M.J. Tabata, D. Srivastava, S. Wakisaka, and K. Kurisu Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis Cell. Tissue Res. 310 2002 201 212
2. R.K. Bruick Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia Proc. Natl. Acad. Sci. U. S. A. 97 2000 9082 9087
3. I. Budihardjo, H. Oliver, M. Lutter, X. Luo, and X. Wang Biochemical pathways of caspase activation during apoptosis Annu. Rev. Cell Dev. Biol. 15 1999 269 290
4. F. Cecconi, G. Alvarez-Bolado, B.I. Meyer, K.A. Roth, and P. Gruss Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development Cell 94 1998 727 737
5. J. Charite, D.G. McFadden, and E.N. Olson The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development Development 127 2000 2461 2470
6. J. Charite, D.G. McFadden, G. Merlo, G. Levi, D.E. Clouthier, M. Yanagisawa, J.A. Richardson, and E.N. Olson Role of Dlx6 in regulation of an endothelin-1-dependent. dHAND branchial arch enhancer Genes Dev. 15 2001 3039 3049
7. M. Chautan, G. Chazal, F. Cecconi, P. Gruss, and P. Golstein Interdigital cell death can occur through a necrotic and caspase-independent pathway Curr. Biol. 9 1999 967 970
8. G. Chen, R. Ray, D. Dubik, L. Shifs, J. Cizeau, R.C Bleackley, S. Saxena, R.D Gietz, and A.H. Greenberg The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis J. Exp. Med. 186 1997 1975 1983
9. M. Cikala, B. Wilm, E. Hobmayer, A. Bottger, and C.N. David Identification of caspases and apoptosis in the simple metazoan Hydra Curr. Biol. 9 1999 959 962
10. W.C. Earnshaw, L.M. Martins, and S.H. Kaufmann Mammalian caspases: structure, activation, substrates, and functions during apoptosis Annu. Rev. Biochem. 68 1999 383 424
11. M. Fernandez-Teran, M.E. Piedra, I.S. Kathiriya, D. Srivastava, J.C. Rodriguez-Rey, and M.A. Ros Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway Development 127 2000 2133 2142
12. K. Guo, G. Searfoss, D. Krolikowski, M. Pagnoni, C. Franks, K. Clark, K.T. Yu, M. Jaye, and Y. Ivashchenko Hypoxia induces the expression of the pro-apoptotic gene BNIP3 Cell Death Differ. 8 2001 367 376
13. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
14. N. Honarpour, C. Du, J.A. Richardson, R.E. Hammer, X. Wang, and J. Herz Adult Apaf-1-deficient mice exhibit male infertility Dev. Biol. 218 2000 248 258
15. M.J. Howard, M. Stanke, C. Schneider, X. Wu, and H. Rohrer The transcription factor dHAND is a downstream effector of BMPs in sympathetic neuron specification Development 127 2000 4073 4081
16. M.D. Jacobson, M. Weil, and M.C. Raff Programmed cell death in animal development Cell 88 1997 347 354
17. R.M. Kluck, E. Bossy-Wetzel, D.R. Green, and D.D. Newmeyer The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132 1136
18. L.A. Kubasiak, O.M. Hernandez, N.H. Bishopric, and K.A. Webster Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3 Proc. Natl. Acad. Sci. U. S. A. 99 2002 12825 12830
19. H. Li, and J. Yuan Deciphering the pathways of life and death Curr. Opin. Cell Biol. 11 1999 261 266
20. P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, E.S. Alnemri, and X. Wang Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 489
21. X. Liu, C.N. Kim, J. Yang, R. Jemmerson, and X. Wang Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c Cell 86 1996 147 157
22. D.G. McFadden, J. Charite, J.A. Richardson, D. Srivastava, A.B. Firulli, and E.N. Olson A GATA-dependent right ventricular enhancer controls HAND2 transcription in the developing heart Development 127 2000 5331 5341
23. K. Miyazaki, H. Yoshida, M. Sasaki, H. Hara, G. Kimura, T.W. Mak, and K. Nomoto Caspase-independent cell death and mitochondrial disruptions observed in the Apaf1-deficient cells J. Biochem. (Tokyo) 129 2001 963 969
24. A.M. Ranger, B.A. Malynn, and S.J. Korsmeyer Mouse models of cell death Nat. Genet. 28 2001 113 118
25. K.M. Regula, K. Ens, and L.A. Kirshenbaum Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes Circ. Res. 91 2002 226 231
26. D. Srivastava, P. Cserjesi, and E.N. Olson A subclass of bHLH proteins required for cardiac morphogenesis Science 270 1995 1995 1999
27. D. Srivastava, T. Thomas, Q. Lin, M.L. Kirby, D. Brown, and E.N. Olson Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND Nat. Genet. 16 1997 154 160
28. T. Thomas, H. Kurihara, H. Yamagishi, Y. Kurihara, Y. Yazaki, E.N. Olson, and D. Srivastava A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme Development 125 1998 3005 3014
29. M.P. Villanueva, A.R. Aiyer, S. Muller, M.T. Pletcher, X. Liu, B. Emanuel, D. Srivastava, and R.H. Reeves Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene Genomics 80 2002 593 600
30. H. Yamagishi, E.N. Olson, and D. Srivastava The basic helix-loop-helix transcription factor, dHAND, is required for vascular development J. Clin. Invest. 105 2000 261 270
31. H. Yamagishi, C. Yamagishi, O. Nakagawa, R.P. Harvey, E.N. Olson, and D. Srivastava The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation Dev. Biol. 239 2001 190 203
32. H. Yanagisawa, D.E. Clouthier, J.A. Richardson, J. Charite, and E.N. Olson Targeted deletion of a branchial arch-specific enhancer reveals a role of HAND2 in craniofacial development Development 130 2003 1069 1078
33. J. Yang, X. Liu, K. Bhalla, C.N. Kim, A.M. Ibrado, J. Cai, T.I. Peng, D.P. Jones, and X. Wang Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
34. M. Yasuda, P. Theodorakis, T. Subramanian, and G. Chinnadurai Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence J. Biol. Chem. 273 1998 12415 12421
35. H. Yoshida, Y.Y. Kong, R. Yoshida, A.J. Elia, A. Hakem, R. Hakem, J.M. Penninger, and T.W. Mak Apaf1 is required for mitochondrial pathways of apoptosis and brain development Cell 94 1998 739 750
36. H. Zou, W.J. Henzel, X. Liu, A. Lutschg, and X. Wang Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 Cell 90 1997 405 413
37. H. Zou, Y. Li, X. Liu, and X. Wang An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 J. Biol. Chem. 274 1999 11549 11556