Bioavailability of phenolic compounds from olive oil and oxidative/antioxidant status at postprandial state in healthy humans

Drugs under Experimental and Clinical Research

Volumn 30, Issue 5-6, 2004, Pages 207-212

  Weinbrenner, T ^a   Fito M ^a   Farre Albaladejo M ^a,b   Saez, G T ^c   Rijken, P ^d   Tormos, C ^c   Coolen, S ^d   De La Torre, R ^a,e   Covas, M I ^a  

^a INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

^d UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

^e UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; GLUTATHIONE PEROXIDASE; HYDROXYTYROSOL; OLIVE OIL; PHENOL DERIVATIVE; TYROSOL;

ADULT; ARTICLE; BODY FAT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG URINE LEVEL; ENZYME ACTIVITY; HUMAN; HYPERLIPIDEMIA; IN VIVO STUDY; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; OXIDATION; OXIDATIVE STRESS; POSTPRANDIAL STATE; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; HUMANS; MALE; OXIDANTS; OXIDATIVE STRESS; PHENOLS; PLANT OILS; POSTPRANDIAL PERIOD;

EID: 11444270680     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. de Lorgeril M., Salen P. Modified Cretan Mediterranean diet in the prevention of coronary heart disease and cancer. World Rev. Nutr. Diet., 87, 1, 2000.
2. Serra-Majem L., Ribas L., Tresserras R., et al. How could changes in diet explain changes in coronary heart disease mortality in Spain? Am. J. Clin. Nutr., 61, 1351S, 1995.
3. Fito M., Covas M.I., Lamuela-Raventós R.M., et al. Protective effect of olive oil and its phenolic compounds against low density lipoprotein oxidation. Lipids, 35, 633, 2000.
4. Visoli F., Bellomo G., Montedoro G., et al. Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. Atherosclerosis, 117, 25, 1995.
5. Wiseman S.A., Tijburg L.B., van de Put F.H. Olive oil phenolics protect LDL and spare vitamin E in the hamster. Lipids, 37, 1053, 2002.
6. Visoli F., Galli C., Bornet F., et al. Olive oilphenolics are dose-dependently absorbed in humans. FEBS Lett., 468, 159, 2000.
7. Regnstrom J., Nilsson J., Tornvall P., et al. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet, 339, 1183, 1992.
8. Weinbrenner T., Cladellas M., Covas M.I., et al. High oxidative stress in patients with stable coronary heart disease. Atherosclerosis, 168, 99, 2003.
9. Fitó M., Gimeno E., Covas M.I., et al. Postprandial and short-term effects of dietary virgin olive oil on oxidant/antioxidant status. Lipids, 37, 245, 2002.
10. Redón J., Oliva M.R., Tormos C., et al. Antioxidant activities and oxidative stress by-products in human hypertension. Hypertension, 41, 1096, 2003.
11. Coolen S.A., van der Ham W., Wiseman S.A. Biomarkers. Proc. European Research on Functional Effects of Dietary Antioxidant (euroFEDA): Benefits and Risks.(Cambridge, 25-28 September 2002). Free Radic. Bol. Med., 36, 120, 2002.
12. Miró-Casas E., Farré A.M., Covas M.I., et al. Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake. Anal. Biochem., 294, 63, 2001.
13. Ceriello A., Taboga C., Tonutti L., et al. Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment. Circulation, 106, 1211, 2002.
14. Dubois C., Beaumier G., Juhel C., et al. Effects of graded amounts (0-50 g) of dietary fat on postprandial lipemia and lipoproteins in normolipidemic adults. Am. J. Clin. Nutr., 67, 31, 1998.
15. Le N.A., Li X., Kyung S., et al. Evidence for the in vivo generation of oxidatively modified epitopes in patients with atherosclerotic endothelium. Metabolism, 49, 1271, 2000.
16. Lechleitner M., Hoppichler F., Foger B., et al. Low-density lipoproteins of the postprandial state induce cellular cholesteryl ester accumulation in macrophages. Arterioscler. Thromb., 14, 1799, 1994.
17. Sutherland W.H., de Jong S.A., Walker R.J., et al. Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men. Atherosclerosis, 160, 195, 2002.
18. Vissers M.N., Zock P.L., Leenen R., et al. Effect of consumption of phenols from olives and extra virgin oil on LDL oxidizability in healthy humans. Free Radic. Res., 35, 619, 2001.
19. Moller P., Loft S. Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies. Am. J. Clin. Nutr., 76, 303, 2002.
20. Basu S. Metabolism of 8-iso-prostaglandin F2alpha. FEBS Lett., 428, 32, 1998.
21. Wolfram R.M., Oguogho A., Efthimiou Y., et al. Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. Prostaglandins Leukot. Essent. Fatty Acids, 66, 529, 2002.
22. Ruiz C., Alegria A., Barbera R., et al. Lipid peroxidation and antioxidant enzyme activities in patients with type 1 diabetes mellitus. Scand. J. Clin. Lab. Invest., 59, 99, 1999.