Rational modification of a selection strategy leads to deoxyribozymes that create native 3′-5′ RNA linkages

Journal of the American Chemical Society

Volumn 126, Issue 50, 2004, Pages 16426-16432

  Coppins, Rebecca L ^a   Silverman, Scott K ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ISOMERS; RNA;

NASCENT LIGATION JUNCTION; NUCLEOPHILIC HYDROXYL GROUP; WATSON-CRICK BASE PAIRING;

ENZYMES;

DEOXYRIBOZYME; MAGNESIUM; RNA; RNA LIGASE;

ALKALINITY; ARTICLE; EMBEDDING; EXPERIMENTAL DESIGN; INCUBATION TIME; ISOMER; LIGATION; LINEAR SYSTEM; PREDICTION; PROTEIN STRUCTURE; REACTION TIME; TEMPERATURE;

BASE SEQUENCE; DNA, CATALYTIC; KINETICS; NUCLEIC ACID CONFORMATION; POLYNUCLEOTIDE LIGASES; RNA; SUBSTRATE SPECIFICITY;

EID: 11444249690     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045817x     Document Type: Article

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